Product image of Mometason Hexal (Mometasone Furoate) supplied by GNH India

Mometason Hexal

Active Ingredient:
Mometasone Furoate
Origin:
EU

Mometason Hexal (Mometasone Furoate)

Mometasone Furoate, the active ingredient in Mometason Hexal, is a corticosteroid presented as a nasal spray for nasal use. It treats allergic rhinitis, including seasonal and perennial forms, in patients requiring local anti‑inflammatory therapy.

GNH India supplies Mometason Hexal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Hexal Pharma Gmbh

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Indications & Clinical Uses

Mometason Hexal is a nasal corticosteroid that reduces inflammation in the nasal mucosa associated with allergic rhinitis.

  • Allergic rhinitis: relieves nasal congestion, sneezing, itching and rhinorrhea.
  • Seasonal allergic rhinitis: controls symptoms triggered by pollen exposure.
  • Perennial allergic rhinitis: manages year‑round nasal inflammation.

How It Works

  • Mometasone furoate binds to glucocorticoid receptors in nasal mucosal cells, altering gene transcription and suppressing the production of inflammatory cytokines and mediators. This reduces vascular permeability, edema, and mucus secretion, providing localized anti‑inflammatory effects with minimal systemic absorption.

Side Effects

Mometason Hexal may cause local and systemic adverse reactions.

Common Side Effects

  • Nasal irritation or burning sensation.
  • Epistaxis (nosebleeds).
  • Headache.
  • Throat irritation or dryness.
  • Cough.
  • Altered taste perception.

Serious or Rare Side Effects

  • Nasal septum perforation.
  • Severe allergic reaction (anaphylaxis).
  • Vision changes or ocular pressure increase.
  • Adrenal suppression with prolonged high‑dose use.
  • Opportunistic fungal infection of the nasal passages.

Precautions & Warnings

Before using Mometason Hexal, consider the following precautions.

  • Pregnancy: consult a healthcare provider; safety not fully established.
  • Elderly: monitor for increased local adverse effects.
  • Recent nasal surgery: postpone use until the surgical site has healed.
  • Concomitant systemic corticosteroids: risk of additive glucocorticoid effects.
  • Known hypersensitivity to mometasone or formulation components: avoid use.
  • Store at room temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Mometason Hexal can interact with other medicines; review the following.

Major Interactions (Avoid)

  • Systemic corticosteroids: may increase overall glucocorticoid exposure.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole): may raise local drug levels.
  • Live vaccines: potential for reduced vaccine efficacy.

Moderate Interactions (Monitor Closely)

  • Antihistamines: may provide additive symptom relief.
  • Decongestant nasal sprays: increased risk of nasal irritation.
  • Antifungal nasal preparations: may affect local microbial balance.

Frequently Asked Questions

Mometason Hexal is a nasal spray containing mometasone furoate indicated for the treatment of allergic rhinitis, including seasonal and perennial forms. It provides local anti‑inflammatory action to relieve nasal congestion, sneezing, itching, and rhinorrhea.

Mometasone furoate binds to glucocorticoid receptors in the cells of the nasal mucosa, modifying gene transcription. This reduces the production of inflammatory cytokines and mediators, leading to decreased swelling, mucus production, and overall nasal inflammation.

The prescribed dose is determined by the treating physician based on symptom severity and patient characteristics. Typical regimens involve one or two sprays per nostril once daily, but exact dosing should follow the healthcare provider’s instructions.

Safety data are limited; the product should be used during pregnancy or lactation only if the potential benefit justifies the potential risk to the fetus or infant. Women who are pregnant or nursing should discuss use with their healthcare professional before starting therapy.

Submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Mometasone furoate is a high‑potency glucocorticoid with minimal systemic absorption, offering effective symptom control at low daily doses. Compared with agents such as fluticasone or budesonide, it provides comparable efficacy with a favorable safety profile when used as directed.

Store at room temperature, below 25 °C, in the original packaging. Protect the spray from moisture and direct sunlight, and keep the cap tightly closed when not in use to maintain product stability.

Insert the spray tip into each nostril while the head is upright. One or two sprays per nostril are typically administered once daily, as instructed by the prescriber. The device should be primed before first use and after periods of non‑use according to the package insert.

Rare but serious adverse events can include nasal septum perforation, severe allergic reactions such as anaphylaxis, adrenal suppression with prolonged high‑dose use, and opportunistic fungal infections of the nasal passages. Seek immediate medical attention if any of these symptoms occur.

Individuals with known hypersensitivity to mometasone furoate or any component of the formulation should avoid the product. It is also contraindicated in patients with active nasal infections, recent nasal surgery, or those receiving systemic corticosteroid therapy without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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