Product image of Mometason Pannonpharma (Mometasone Furoate) supplied by GNH India

Mometason Pannonpharma

Active Ingredient:
Mometasone Furoate
Origin:
EU

Mometason Pannonpharma (Mometasone Furoate)

Mometasone furoate, the active ingredient in Mometason, is a glucocorticoid presented as a nasal spray for intranasal use. It reduces inflammation in the nasal passages and is indicated for allergic rhinitis, seasonal allergic rhinitis and nasal polyps in both adults and children.

GNH India supplies Mometason as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with distribution across EU and other regulated markets, ensuring quality and regulatory compliance.

Manufacturer / TM Owner

Pannonpharma Kft.

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Indications & Clinical Uses

Mometason (mometasone furoate) is a nasal corticosteroid that acts on inflammatory pathways of the nasal mucosa.

  • Allergic rhinitis: relieves nasal congestion, itching, sneezing and rhinorrhea.
  • Seasonal allergic rhinitis: controls symptoms triggered by pollen or seasonal allergens.
  • Nasal polyps: reduces polyp size and improves nasal airflow.

How It Works

  • Mometasone furoate binds to intracellular glucocorticoid receptors in nasal epithelial cells, forming a receptor‑ligand complex that translocates to the nucleus and modulates gene transcription. This down‑regulates pro‑inflammatory cytokines, chemokines and adhesion molecules, decreasing vascular permeability, edema and inflammatory cell infiltration in the nasal mucosa.

Side Effects

Mometason may cause local and systemic adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Nasal irritation or burning: mild discomfort in the nostrils.
  • Headache: occasional mild headache.
  • Epistaxis: nosebleeds.
  • Unpleasant taste: bitter taste after use.

Serious or Rare Side Effects

  • Nasal septal perforation: rare tissue damage.
  • Vision changes: blurred vision or cataract formation.
  • Adrenal suppression: systemic glucocorticoid effect with prolonged use.
  • Severe allergic reaction: anaphylaxis, hives, swelling.
  • Increased intra‑ocular pressure: risk of glaucoma.

Precautions & Warnings

Before using Mometason, consider the following precautions.

  • Pregnancy: safety not established; use only if benefit outweighs risk.
  • Pediatric use: safety profile established for children aged 2 years and older.
  • Systemic corticosteroid use: avoid concurrent high‑dose systemic steroids.
  • Infection: monitor for fungal or bacterial sinus infections.
  • Surgery: discontinue before nasal or sinus surgery as advised by the surgeon.
  • Store at ambient temperature below 25°C: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Mometason can interact with other medicines; review the following.

Major Interactions (Avoid)

  • Systemic corticosteroids: additive systemic glucocorticoid effects.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): may increase local exposure.
  • Antifungal azoles: similar risk of increased exposure.

Moderate Interactions (Monitor Closely)

  • Nasal decongestants: may increase local irritation.
  • Antihistamines: generally safe but monitor symptom control.
  • Live vaccines: effectiveness may be reduced; consider timing of vaccination.

Frequently Asked Questions

Mometason is a nasal spray containing mometasone furoate, a glucocorticoid that is used to treat allergic rhinitis, seasonal allergic rhinitis and nasal polyps by reducing inflammation in the nasal passages.

Mometasone furoate binds to glucocorticoid receptors inside nasal epithelial cells, altering gene transcription to suppress the production of inflammatory cytokines, chemokines and other mediators, which decreases swelling and irritation of the nasal mucosa.

The prescribed dose of Mometason is determined by a qualified healthcare professional. Typical regimens involve one or two sprays per nostril once daily, but the exact amount and frequency should follow the prescriber’s instructions.

Safety data for mometasone furoate in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by the treating physician.

To order Mometason, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Mometason and fluticasone are both intranasal glucocorticoids with similar efficacy for allergic rhinitis. Mometasone furoate has a high receptor affinity and a low systemic bioavailability, which may result in a slightly lower risk of systemic side effects compared with some alternatives.

Mometason should be stored at ambient temperature below 25 °C, in its original packaging, protected from moisture and direct sunlight. Keep the spray away from children and do not freeze the product.

Mometason is administered as a nasal spray. The patient gently tilts the head forward, inserts the nozzle into each nostril, and sprays the prescribed number of sprays while breathing in gently through the nose.

Serious risks include nasal septal perforation, adrenal suppression with prolonged high‑dose use, severe allergic reactions such as anaphylaxis, and increased intra‑ocular pressure that could lead to glaucoma. Any of these symptoms require immediate medical attention.

Mometason should be avoided in individuals with known hypersensitivity to mometasone furoate or any component of the formulation, in patients with active untreated fungal, bacterial or viral infections of the nose, and in those who have recently undergone nasal surgery unless advised otherwise by a clinician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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