Product image of Mometasona Ciclum (Mometasone Furoate) supplied by GNH India

Mometasona Ciclum

Active Ingredient:
Mometasone Furoate
Origin:
EU

Mometasona Ciclum (Mometasone Furoate)

Mometasone furoate, the active ingredient in Mometasona Ciclum, is a corticosteroid presented as a nasal spray for intranasal use. It reduces inflammation in the nasal passages and is indicated for allergic rhinitis and other nasal inflammatory conditions in adults and children.

GNH India supplies Mometasona Ciclum as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Ciclum Farma Unipessoal Lda.

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Indications & Clinical Uses

Mometasone furoate nasal spray is used to treat inflammatory conditions of the nasal mucosa.

  • Seasonal allergic rhinitis: alleviates nasal congestion, itching and sneezing.
  • Perennial allergic rhinitis: provides sustained relief of nasal symptoms throughout the year.
  • Nasal polyps: reduces polyp size and improves nasal airflow.
  • Non‑allergic rhinitis: helps control nasal inflammation and congestion.

How It Works

  • Mometasone furoate binds to intracellular glucocorticoid receptors in nasal epithelial cells, forming a receptor complex that translocates to the nucleus. This complex modulates gene transcription, suppressing pro‑inflammatory cytokines, chemokines, and adhesion molecules while enhancing anti‑inflammatory proteins. The net effect is reduced vascular permeability, edema, and inflammatory cell infiltration in the nasal mucosa, leading to symptom relief.

Side Effects

Mometasone furoate nasal spray may cause local and systemic adverse reactions.

Common Side Effects

  • Nasal irritation or burning
  • Headache
  • Epistaxis (nosebleed)
  • Unpleasant taste
  • Throat irritation
  • Cough

Serious or Rare Side Effects

  • Nasal septal perforation
  • Vision changes such as cataract or glaucoma
  • Severe allergic reaction (anaphylaxis)
  • Suppression of adrenal function
  • Fungal infection of the nasal mucosa

Precautions & Warnings

Use of Mometasona Ciclum should follow medical guidance and consider patient‑specific factors.

  • Use only as prescribed: follow the prescriber's instructions for frequency and duration.
  • Avoid spray contact with eyes: rinse with water if accidental.
  • Do not share device: risk of cross‑contamination.
  • Monitor for signs of infection: report persistent nasal bleeding or ulceration.
  • Assess risk in patients with uncontrolled diabetes or glaucoma: consult healthcare provider.
  • Store at below 25°C: keep in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Mometasone furoate nasal spray can interact with other medicines that affect corticosteroid activity or nasal mucosa.

Major Interactions (Avoid)

  • Systemic corticosteroids: increased risk of systemic effects.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole): may raise local exposure.
  • Antifungal azoles (e.g., itraconazole): potential increased glucocorticoid activity.

Moderate Interactions (Monitor Closely)

  • Nasal decongestant sprays: may increase local irritation.
  • Antihistamines: monitor overall symptom control.
  • Live attenuated vaccines: consider timing due to possible immunosuppression.

Frequently Asked Questions

Mometasona Ciclum contains mometasone furoate, a nasal corticosteroid used to treat inflammatory nasal conditions such as seasonal and perennial allergic rhinitis, nasal polyps, and non‑allergic rhinitis. It helps relieve congestion, itching, sneezing, and nasal blockage by reducing local inflammation.

Mometasone furoate binds to glucocorticoid receptors in nasal epithelial cells, altering gene transcription to suppress pro‑inflammatory cytokines and chemokines while enhancing anti‑inflammatory proteins. This reduces swelling, mucus production, and immune cell infiltration, leading to symptom improvement in the nasal passages.

The specific dosing regimen for Mometasona Ciclum is determined by the prescribing healthcare professional based on the patient’s age, condition severity, and response to therapy. Patients should follow the prescriber’s instructions and the product label for the correct number of sprays and frequency.

Safety data for mometasone furoate nasal spray in pregnancy and lactation are limited. It should be used only if the potential benefit justifies any potential risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss use with their healthcare provider.

To order, visit the product page on gnhindia.com, enter the required quantity, and submit the enquiry form. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and import documentation.

Mometasone furoate is a high‑potency intranasal corticosteroid with a low systemic bioavailability, offering strong anti‑inflammatory effects while minimizing systemic exposure. Compared with older agents such as fluticasone or budesonide, it often provides comparable or superior symptom control with once‑daily dosing for many patients.

Store the nasal spray at temperatures below 25 °C (77 °F), in its original packaging, and protect it from moisture and direct sunlight. Do not freeze the product. Keep the device out of reach of children and check the expiry date before use.

Mometasona Ciclum is administered as a nasal spray. The patient should gently blow the nose, tilt the head slightly forward, insert the nozzle into one nostril, and press the actuator while breathing in gently through the nose. The same procedure is repeated in the other nostril if required.

Serious but rare risks include nasal septal perforation, suppression of the hypothalamic‑pituitary‑adrenal axis, cataract or glaucoma development, severe allergic reactions (anaphylaxis), and opportunistic fungal infections of the nasal mucosa. Any unusual symptoms should be reported to a healthcare professional promptly.

Patients with known hypersensitivity to mometasone furoate or any component of the formulation should avoid use. Individuals with active untreated infections of the nasal passages, recent nasal surgery, or severe ocular herpes should also consult a physician before using this nasal corticosteroid.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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