Product image of Mometasona Furoato Kern Pharma (Mometasone Furoate) supplied by GNH India

Mometasona Furoato Kern Pharma

Active Ingredient:
Mometasone Furoate
Origin:
EU

Mometasona Furoato Kern Pharma (Mometasone Furoate)

Mometasone furoate, the active ingredient in Mometasona Furoato Kern Pharma, is a corticosteroid presented as a nasal spray for intranasal use. It reduces nasal inflammation and is used to treat allergic rhinitis and other nasal inflammatory conditions in adults and children.

GNH India supplies Mometasona Furoato Kern Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Kern Pharma, S.L.

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Indications & Clinical Uses

  • Mometasone furoate nasal spray is indicated for conditions affecting the nasal passages where inflammation is a primary component.
  • Allergic rhinitis: reduces nasal congestion, itching, sneezing and rhinorrhea.
  • Nasal polyps: decreases polyp size and improves nasal airflow after surgical removal.
  • Non‑allergic rhinitis: alleviates nasal inflammation and associated symptoms.

How It Works

  • Mometasone furoate binds to intracellular glucocorticoid receptors, forming a complex that translocates to the nucleus and modulates gene transcription. This action suppresses the production of pro‑inflammatory cytokines, chemokines, and adhesion molecules, leading to reduced vascular permeability, edema, and inflammatory cell infiltration in the nasal mucosa.

Side Effects

Mometasone furoate nasal spray may cause local and systemic adverse reactions.

Common Side Effects

  • Nasal irritation or burning sensation.
  • Headache.
  • Epistaxis (nosebleeds).
  • Throat irritation or dryness.
  • Altered taste perception.

Serious or Rare Side Effects

  • Nasal fungal infection (e.g., Candida).
  • Adrenal suppression with prolonged high‑dose use.
  • Severe or persistent nosebleeds.
  • Vision changes such as cataracts or glaucoma.
  • Anaphylactic or severe allergic reactions.

Precautions & Warnings

  • Before using Mometasone furoate nasal spray, consider the following precautions.
  • Pregnancy: consult a healthcare provider before use.
  • Pediatric use: safety not established for children under 2 years of age.
  • Concurrent nasal surgery: avoid using shortly before or after the procedure.
  • Long‑term use: monitor for signs of adrenal suppression.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Mometasone furoate nasal spray can interact with other medications; review the following.

Major Interactions (Avoid)

  • Systemic corticosteroids: increased risk of systemic glucocorticoid effects.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): may raise local drug exposure.
  • Immunosuppressants: potential additive immunosuppression.

Moderate Interactions (Monitor Closely)

  • Antihistamines: may increase nasal dryness.
  • Decongestant nasal sprays: concurrent use may heighten local irritation.

Frequently Asked Questions

Mometasona Furoato Kern Pharma is a nasal spray containing mometasone furoate, a corticosteroid used to treat inflammatory nasal conditions such as allergic rhinitis, nasal polyps, and non‑allergic rhinitis. It helps relieve symptoms like congestion, sneezing, itching, and runny nose by reducing local inflammation.

Mometasone furoate works by binding to glucocorticoid receptors inside nasal mucosal cells. This complex alters gene transcription, suppressing the release of inflammatory mediators such as cytokines and prostaglandins, which reduces swelling, mucus production, and immune cell activity in the nasal passages.

The appropriate dose is determined by the prescribing healthcare professional based on the patient’s age, condition severity, and response to therapy. Typical regimens involve one or two sprays per nostril once daily, but exact instructions should always follow the prescriber’s order.

Safety data for mometasone furoate in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss use with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Mometasone furoate is a high‑potency intranasal corticosteroid with a low systemic bioavailability, offering effective symptom control at once‑daily dosing. Compared with alternatives such as fluticasone propionate, mometasone often provides comparable efficacy with a similar safety profile, though individual response and tolerability may vary.

Store the nasal spray at room temperature, preferably below 25 °C (77 °F). Keep it in the original packaging to protect from moisture and direct sunlight. Do not freeze the product, and ensure the cap is tightly closed when not in use.

The spray is intended for intranasal use. Gently blow the nose, tilt the head slightly forward, insert the nozzle into one nostril, and press the pump while breathing in gently through the nose. Repeat in the other nostril if prescribed, and avoid blowing the nose immediately after dosing.

Serious risks, though rare, include nasal fungal infections, adrenal suppression with prolonged high‑dose use, severe or persistent nosebleeds, vision changes such as cataracts or glaucoma, and systemic allergic reactions including anaphylaxis. Patients should seek medical attention if any of these occur.

The spray should be avoided in individuals with known hypersensitivity to mometasone furoate or any component of the formulation. It is also contraindicated in patients with active untreated fungal, viral, or bacterial infections of the nasal passages, and in children under the age recommended by the prescriber.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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