Product image of Mometasona Generis (Mometasone Furoate Anhydrous) supplied by GNH India

Mometasona Generis

Active Ingredient:
Mometasone Furoate Anhydrous
Origin:
EU

Mometasona Generis (Mometasone Furoate Anhydrous)

Mometasone furoate, the active ingredient in Mometasona Generis, is a corticosteroid presented as a nasal spray for intranasal use. It reduces nasal inflammation and is indicated for the treatment of allergic rhinitis and nasal polyps in adults and adolescents, helping to relieve congestion, sneezing and nasal discharge.

GNH India supplies Mometasona Generis as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Generis Farmacêutica, S.A.

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Indications & Clinical Uses

Mometasona Generis is a nasal corticosteroid that acts on inflammatory pathways of the nasal mucosa.

  • Allergic rhinitis: reduces nasal inflammation and symptoms such as congestion, sneezing and itching.
  • Nasal polyps: decreases polyp size and improves nasal airflow.
  • Non‑allergic rhinitis: alleviates nasal congestion and discharge.

How It Works

  • Mometasone furoate binds to intracellular glucocorticoid receptors in nasal epithelial cells, altering gene transcription. This down‑regulates pro‑inflammatory cytokines, chemokines and adhesion molecules, leading to reduced inflammatory cell infiltration and edema in the nasal mucosa, thereby improving nasal patency and symptom control.

Side Effects

Common Side Effects

  • Nasal irritation or burning sensation.
  • Epistaxis (nosebleeds).
  • Headache.
  • Sore throat or cough.
  • Altered taste or smell.

Serious or Rare Side Effects

  • Fungal infection of the nasal passages.
  • Severe or persistent epistaxis.
  • Adrenal suppression with systemic effects.
  • Vision changes such as cataracts or glaucoma.
  • Anaphylactic or severe allergic reactions.

Precautions & Warnings

Before using Mometasona Generis, consider the following precautions:

  • Pregnancy: consult a healthcare professional before use.
  • Lactation: discuss potential risks with a physician.
  • Elderly patients: monitor for systemic glucocorticoid effects.
  • Active nasal infection: avoid use until infection resolves.
  • Concurrent nasal surgery: postpone administration until post‑operative healing.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Mometasona Generis may interact with other medicines as follows.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole): may increase systemic exposure.
  • Systemic corticosteroids: risk of additive glucocorticoid effects.
  • Live vaccines: may reduce vaccine efficacy.

Moderate Interactions (Monitor Closely)

  • Antifungal azoles (e.g., itraconazole): may raise local drug levels.
  • Ritonavir or other protease inhibitors: potential increase in exposure.
  • St. John’s wort or other enzyme inducers: may reduce effectiveness.

Frequently Asked Questions

Mometasona Generis is a nasal spray containing mometasone furoate, a corticosteroid indicated for the management of allergic rhinitis and nasal polyps. It helps to reduce nasal inflammation, congestion, sneezing, and itching, improving overall nasal airflow.

Mometasone furoate binds to glucocorticoid receptors in the cells lining the nasal mucosa. This interaction modifies gene transcription, leading to decreased production of inflammatory cytokines and reduced recruitment of immune cells, which together diminish swelling and irritation in the nasal passages.

The specific dosing regimen for Mometasona Generis is determined by the prescribing healthcare professional based on the patient’s age, severity of symptoms, and clinical response. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for mometasone furoate nasal spray in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using the product.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Mometasona Generis contains mometasone furoate, which is a high‑potency intranasal corticosteroid with a favorable safety profile when used as directed. Compared with lower‑potency agents such as fluticasone or budesonide, mometasone may achieve symptom control at lower daily doses, but the choice of therapy should be individualized by the prescriber.

Store Mometasona Generis at room temperature, preferably below 25 °C. Keep the spray bottle in its original packaging, protect it from excessive moisture and direct sunlight, and ensure the cap is tightly closed when not in use.

Mometasona Generis is administered as a nasal spray. The patient should gently blow the nose, tilt the head slightly forward, insert the nozzle into one nostril, and spray the prescribed number of sprays while breathing in gently. The process is then repeated in the other nostril if directed by the prescriber.

Serious risks, though rare, include fungal infection of the nasal mucosa, severe or persistent nosebleeds, adrenal suppression leading to systemic glucocorticoid effects, and severe allergic reactions such as anaphylaxis. Patients should seek immediate medical attention if they experience any of these symptoms.

Mometasona Generis should be avoided in individuals with known hypersensitivity to mometasone furoate or any component of the formulation. It is also contraindicated in patients with active, untreated nasal infections or recent nasal surgery unless cleared by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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