Product image of Mometasona furoato Cipla (Mometasone) supplied by GNH India

Mometasona furoato Cipla

Active Ingredient:
Mometasone
Origin:
EU

Mometasona furoato Cipla (Mometasone)

Mometasone, the active ingredient in Mometasona furoato Cipla, is a corticosteroid presented as a nasal spray for nasal use. It treats allergic rhinitis, seasonal allergic rhinitis and nasal polyps in adults and children as appropriate.

GNH India supplies Mometasona furoato Cipla as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Cipla Europe Nv

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Indications & Clinical Uses

  • Mometasone furoate is a topical corticosteroid used to manage inflammatory conditions of the nasal passages.
  • Allergic rhinitis: decreases nasal inflammation, relieving congestion, rhinorrhea, itching and sneezing in patients with perennial allergic rhinitis.
  • Seasonal allergic rhinitis: controls seasonal nasal symptoms by reducing inflammatory mediator release during pollen exposure.
  • Nasal polyps: diminishes polyp size and associated obstruction, improving nasal breathing in adults with diagnosed nasal polyposis.

How It Works

  • Mometasone furoate binds to intracellular glucocorticoid receptors in nasal mucosal cells, forming a complex that translocates to the nucleus and inhibits transcription of pro‑inflammatory cytokines, chemokines and adhesion molecules. This suppresses the inflammatory cascade, reducing edema, mucus production and cellular infiltration in the nasal passages.

Side Effects

Mometasone nasal spray may cause local or systemic adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Nasal irritation or burning sensation.
  • Sneezing or mild nosebleeds.
  • Dryness of nasal mucosa.
  • Headache.

Serious or Rare Side Effects

  • Severe epistaxis.
  • Nasal septal perforation.
  • Vision changes or cataract formation (rare with prolonged use).

Precautions & Warnings

Before using Mometasone nasal spray, consider the following precautions to ensure safe and effective therapy.

  • Indication verification: confirm diagnosis of allergic rhinitis, seasonal allergic rhinitis or nasal polyps.
  • Duration of use: limit continuous use to recommended period, typically not exceeding several weeks without medical review.
  • Local infection: avoid use if nasal infection or recent nasal surgery is present.
  • Systemic corticosteroid exposure: assess cumulative steroid dose if patient uses other glucocorticoids.
  • Pregnancy and lactation: discuss potential risks with healthcare provider.
  • Store at ambient temperature: keep below 25 °C, in original container, protect from moisture and direct sunlight.

Avoid Interactions

Mometasone nasal spray can interact with certain medicines, primarily through additive corticosteroid effects or altered metabolism.

Major Interactions (Avoid)

  • Systemic corticosteroids: concurrent use may increase risk of systemic glucocorticoid side effects.
  • CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): may raise local drug exposure, potentially enhancing adverse effects.

Moderate Interactions (Monitor Closely)

  • Antifungal azoles (e.g., fluconazole): monitor for increased nasal irritation.
  • Immunosuppressants (e.g., cyclosporine): watch for heightened infection risk.
  • Antihistamines: no significant interaction but may be used concomitantly for symptom control.

Frequently Asked Questions

Mometasona furoato Cipla is a nasal spray containing mometasone furoate, a corticosteroid indicated for the treatment of allergic rhinitis, seasonal allergic rhinitis and nasal polyps. It works locally in the nasal passages to reduce inflammation and relieve symptoms such as congestion, sneezing and nasal obstruction.

Mometasone binds to glucocorticoid receptors in the cells lining the nasal mucosa. The drug‑receptor complex enters the cell nucleus and suppresses the transcription of genes that code for pro‑inflammatory cytokines, chemokines and adhesion molecules, thereby decreasing swelling, mucus production and immune cell infiltration.

The specific dose and frequency are determined by the prescribing healthcare professional based on the patient’s age, severity of symptoms and clinical response. Typical regimens involve one or two sprays per nostril once daily, but the exact regimen should always follow the prescriber’s instructions.

Safety data for mometasone nasal spray in pregnancy and lactation are limited. The product should only be used if the potential benefit justifies any potential risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss use with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Mometasone furoate is a high‑potency intranasal corticosteroid with a low systemic bioavailability, similar to fluticasone propionate. Compared with some older agents, mometasone often requires fewer daily sprays to achieve comparable symptom control, but the choice of product depends on individual response, tolerability and prescriber preference.

The nasal spray should be stored at ambient temperature, preferably below 25 °C, in its original packaging. Protect it from moisture, excessive heat and direct sunlight. Keep the device upright and avoid freezing. Do not use the product beyond the expiration date printed on the label.

Before each use, gently shake the bottle, remove the cap and prime the spray if it is the first use. Tilt the head slightly forward, insert the nozzle into one nostril, close the opposite nostril with a finger, and press the actuator to deliver the prescribed number of sprays. Breathe in gently through the nose and repeat in the other nostril if instructed.

Serious but rare adverse events include severe nosebleeds, perforation of the nasal septum and, with prolonged high‑dose use, systemic corticosteroid effects such as adrenal suppression, cataracts or glaucoma. Patients should report any persistent bleeding, visual changes or signs of infection to their healthcare provider promptly.

The spray should be avoided in individuals with known hypersensitivity to mometasone or any component of the formulation, in those with active untreated nasal infections, recent nasal surgery, or severe nasal trauma. Patients on systemic corticosteroids or with uncontrolled systemic fungal infections should also discuss use with a clinician before starting therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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