Product image of Mometasone Eg (Mometasone Furoate) supplied by GNH India

Mometasone Eg

Active Ingredient:
Mometasone Furoate
Origin:
EU

Mometasone Eg (Mometasone Furoate)

Mometasone furoate, the active ingredient in Mometasone Eg, is a corticosteroid presented as an unspecified strength nasal spray for nasal use. It reduces inflammation associated with allergic rhinitis and nasal polyps in adults and children.

GNH India supplies Mometasone Eg as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Eg S.P.A.

1
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Indications & Clinical Uses

Mometasone furoate nasal spray acts on inflammatory pathways of the nasal mucosa to manage allergic and polyp‑related conditions.

  • Allergic rhinitis: relieves nasal congestion, itching and sneezing caused by seasonal or perennial allergens.
  • Seasonal allergic rhinitis: provides symptom control during pollen seasons.
  • Nasal polyps: reduces polyp size and improves nasal airflow in patients with chronic nasal polyposis.

How It Works

  • Mometasone furoate binds to intracellular glucocorticoid receptors in nasal epithelial cells, altering gene transcription. This down‑regulates pro‑inflammatory cytokines, chemokines and adhesion molecules, leading to decreased recruitment and activation of inflammatory cells in the nasal mucosa and thereby reducing swelling and mucus production.

Side Effects

Mometasone furoate nasal spray may cause local and systemic adverse reactions.

Common Side Effects

  • Nasal irritation or burning sensation.
  • Epistaxis (nosebleeds).
  • Headache.
  • Sore throat.
  • Cough.

Serious or Rare Side Effects

  • Adrenal suppression with prolonged high‑dose use.
  • Cataract formation or glaucoma.
  • Severe allergic reaction (anaphylaxis).
  • Opportunistic fungal infection of the nasal passages.
  • Nasal septum perforation.

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Assess patient history: evaluate recent nasal surgery, infection or trauma.
  • Review systemic corticosteroid use: avoid cumulative systemic exposure.
  • Monitor for signs of adrenal insufficiency during long‑term treatment.
  • Caution in patients with glaucoma or cataracts: regular ophthalmologic review may be needed.
  • Avoid use in children under the age recommended by local labeling without specialist advice.
  • Store at room temperature: keep in the original container, protect from moisture and direct heat.

Avoid Interactions

Mometasone furoate nasal spray can interact with other medications that affect corticosteroid metabolism or increase systemic exposure.

Major Interactions (Avoid)

  • Concurrent systemic corticosteroids: heightened risk of systemic glucocorticoid effects.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir): may increase local drug levels.

Moderate Interactions (Monitor Closely)

  • Antifungal azoles (e.g., itraconazole): monitor for local irritation.
  • Nasal decongestants (e.g., oxymetazoline): assess for additive nasal mucosa effects.
  • Immunosuppressants (e.g., cyclosporine): watch for enhanced immunosuppression.

Frequently Asked Questions

Mometasone Eg is a nasal spray containing mometasone furoate that is prescribed to treat allergic rhinitis, including seasonal and perennial forms, and to reduce the size of nasal polyps, helping to improve nasal airflow and relieve congestion.

Mometasone furoate binds to glucocorticoid receptors in the cells lining the nasal mucosa. This interaction modifies gene expression, suppressing the production of inflammatory mediators and preventing activation of inflammatory cells, which reduces swelling and mucus in the nose.

The specific dose and frequency of Mometasone Eg are determined by the prescribing clinician based on the patient’s age, severity of symptoms, and clinical response. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for mometasone furoate nasal spray in pregnancy and lactation are limited. Healthcare providers usually weigh the potential benefits against possible risks before prescribing it to pregnant or nursing women. Patients should discuss any concerns with their doctor.

To request Mometasone Eg, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Mometasone furoate is a potent, once‑daily glucocorticoid with high local anti‑inflammatory activity and minimal systemic absorption compared with some older nasal steroids. Its efficacy in controlling allergic rhinitis and nasal polyps is comparable to fluticasone or budesonide, while offering a convenient dosing schedule.

Mometasone Eg should be stored at room temperature, below 25 °C, in its original packaging. Keep the spray bottle tightly closed, protect it from moisture and direct sunlight, and avoid freezing the product.

The spray is used intranasally. The patient gently shakes the bottle, primes it if required, tilts the head slightly forward, inserts the tip into one nostril, and sprays the prescribed number of sprays while breathing in gently. The process is repeated in the other nostril as directed.

Serious risks, though rare, include adrenal suppression with prolonged high‑dose use, cataract or glaucoma development, severe allergic reactions such as anaphylaxis, and opportunistic fungal infections of the nasal passages. Patients should report any unusual symptoms promptly.

Mometasone Eg is contraindicated in individuals with known hypersensitivity to mometasone furoate or any component of the formulation. It should also be avoided in patients with active untreated nasal infections, recent nasal surgery, or those for whom systemic corticosteroid exposure is contraindicated.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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