Product image of Mometason Furoát Cipla (Mometasone Furoate Monohydrate) supplied by GNH India

Mometason Furoát Cipla

Active Ingredient:
Mometasone Furoate Monohydrate
Origin:
EU

Mometason Furoát Cipla (Mometasone Furoate Monohydrate)

Mometasone furoate, the active ingredient in Mometason Furoát Cipla, is a corticosteroid presented as an inhalation formulation for inhalation use. It reduces airway inflammation in patients with asthma and chronic obstructive pulmonary disease, helping to improve breathing and prevent exacerbations.

GNH India supplies Mometason Furoát Cipla as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Cipla Europe Nv

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Indications & Clinical Uses

Mometason Furoát Cipla is a glucocorticoid inhaler that targets airway inflammation in chronic respiratory diseases.

  • Asthma: improves lung function and reduces the frequency of exacerbations.
  • Chronic obstructive pulmonary disease (COPD): decreases airway inflammation and eases breathing difficulty.
  • Persistent airway hyperresponsiveness: helps maintain control of symptoms in patients with reversible airway obstruction.

How It Works

  • Mometasone furoate acts as an agonist of the glucocorticoid receptor in airway epithelial and immune cells. Binding triggers transcriptional changes that suppress pro‑inflammatory cytokine production, inhibit leukocyte migration, and reduce edema, thereby lowering airway inflammation and improving airflow in the respiratory tract.

Side Effects

Mometason Furoát Cipla may cause a range of adverse reactions, most of which are related to local exposure of the airways.

Common Side Effects

  • Oral thrush (candidiasis): fungal growth in the mouth.
  • Hoarseness or dysphonia: changes in voice quality.
  • Cough or throat irritation: mild discomfort after inhalation.
  • Headache: transient mild pain.
  • Nasal irritation: dryness or soreness.
  • Upper respiratory tract infection: mild cold‑like symptoms.

Serious or Rare Side Effects

  • Paradoxical bronchospasm: sudden worsening of breathing.
  • Severe allergic reaction (anaphylaxis): rash, swelling, difficulty breathing.
  • Suppression of adrenal function: signs of cortisol deficiency.
  • Osteoporosis or bone loss with long‑term high‑dose use.
  • Glaucoma or cataract formation with prolonged exposure.
  • Pneumonia: especially in patients with COPD.

Precautions & Warnings

Before prescribing Mometason Furoát Cipla, clinicians should consider several safety aspects.

  • Monitor for oral thrush: advise patients to rinse mouth after each inhalation.
  • Assess for signs of adrenal suppression: especially with high‑dose or prolonged therapy.
  • Use caution in patients with active infections: respiratory or systemic infections may worsen.
  • Avoid abrupt discontinuation: taper dose to prevent rebound inflammation.
  • Evaluate bone health: consider calcium and vitamin D supplementation for long‑term users.
  • Store at ambient temperature: keep below 25 °C, protect from moisture and direct sunlight.

Avoid Interactions

Mometason Furoát Cipla can interact with other medicines that affect systemic corticosteroid exposure or immune function.

Major Interactions (Avoid)

  • Strong CYP3A4 inducers (e.g., rifampicin, phenytoin): may reduce drug efficacy.
  • Systemic immunosuppressants (e.g., azathioprine, cyclosporine): increase risk of infection.

Moderate Interactions (Monitor Closely)

  • Antifungal azoles (e.g., ketoconazole): may modestly raise systemic levels.
  • Live vaccines: potential reduced vaccine efficacy.
  • Diuretics (e.g., furosemide): may increase risk of hypokalemia when systemic absorption occurs.
  • Non‑steroidal anti‑inflammatory drugs (NSAIDs): monitor for additive gastrointestinal irritation.

Frequently Asked Questions

Mometason Furoát Cipla is an inhaled corticosteroid indicated for the long‑term management of asthma and chronic obstructive pulmonary disease (COPD). It works by reducing airway inflammation, helping to improve breathing, decrease symptom frequency, and lower the risk of disease exacerbations.

Mometasone furoate binds to glucocorticoid receptors in airway cells, altering gene transcription to suppress inflammatory cytokines, reduce leukocyte infiltration, and limit mucus production. This anti‑inflammatory action decreases swelling and hyper‑responsiveness of the airways, leading to better airflow and symptom control.

The specific dose and frequency of Mometason Furoát Cipla are determined by the prescribing clinician based on the patient’s age, disease severity, and response to therapy. Healthcare professionals tailor the inhalation regimen to achieve optimal control while minimizing potential side effects.

The safety of Mometason Furoát Cipla in pregnancy and lactation has not been definitively established. Physicians should weigh the potential benefits against possible risks and consider alternative treatments when appropriate. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss options with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request trade or institutional credentials. After verification, the team provides pricing, availability, shipping details (including any cold‑chain needs), and assists with import documentation.

Mometason Furoát Cipla contains mometasone furoate, a potent glucocorticoid with high local anti‑inflammatory activity and low systemic absorption. Compared with agents such as budesonide or fluticasone, it offers similar efficacy for asthma and COPD control, but dosing frequency and device compatibility may differ, influencing patient preference and adherence.

Store the inhaler at ambient temperature, preferably below 25 °C. Keep it in the original packaging, protect it from moisture and direct sunlight, and ensure the mouthpiece remains clean. Do not expose the product to extreme heat or freeze it, as this could affect the formulation.

The medication is delivered via a metered‑dose inhaler or dry‑powder inhaler, as specified by the product label. Patients should inhale a full dose after a slow, deep breath, hold their breath for a few seconds, and then exhale slowly. Rinsing the mouth after each use helps reduce the risk of oral thrush.

Serious risks include paradoxical bronchospasm, severe allergic reactions (anaphylaxis), adrenal suppression with high‑dose or prolonged use, and rare systemic effects such as osteoporosis or cataract formation. Patients should be educated to recognize early signs of these events and seek medical attention promptly.

Patients with known hypersensitivity to mometasone furoate, other corticosteroids, or any excipients in the inhaler should avoid its use. Caution is also advised for individuals with active, untreated infections, uncontrolled diabetes, or a history of severe osteoporosis, and the decision should be made by a qualified healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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