Product image of Mometasone Furoate Monohydrate Aurobindo (Mometasone Furoate) supplied by GNH India

Mometasone Furoate Monohydrate Aurobindo

Active Ingredient:
Mometasone Furoate
Origin:
EU

Mometasone Furoate Monohydrate Aurobindo (Mometasone Furoate)

Mometasone furoate, the active ingredient in Mometasone Furoate Monohydrate Aurobindo, is a corticosteroid presented as a nasal spray for nasal use. It treats allergic rhinitis, including seasonal and perennial forms, in adults and children.

GNH India supplies Mometasone Furoate Monohydrate Aurobindo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Aurobindo Pharma B.V.

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Indications & Clinical Uses

  • Mometasone furoate is a topical corticosteroid indicated for inflammatory conditions of the nasal mucosa.
  • Allergic rhinitis: reduces nasal congestion, itching, and sneezing.
  • Seasonal allergic rhinitis: provides rapid relief of seasonal allergy symptoms.
  • Perennial allergic rhinitis: offers sustained control of year‑round nasal inflammation.

How It Works

  • Mometasone furoate is a synthetic glucocorticoid that penetrates nasal epithelial cells and binds intracellular glucocorticoid receptors. The drug‑receptor complex translocates to the nucleus, where it modulates gene transcription, decreasing production of inflammatory mediators such as cytokines, prostaglandins, and leukotrienes, thereby suppressing local immune responses and reducing nasal mucosal edema.

Side Effects

Mometasone furoate nasal spray may cause adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Nasal irritation or burning
  • Headache
  • Sneezing or mild nosebleeds
  • Altered taste or throat irritation

Serious or Rare Side Effects

  • Nasal septal perforation
  • Severe allergic reaction (anaphylaxis)
  • Adrenal suppression with prolonged use

Precautions & Warnings

  • Before using Mometasone furoate nasal spray, consider the following safety measures.
  • Pregnancy: consult a healthcare provider; safety not established.
  • Breastfeeding: use with caution; limited data available.
  • Use in children: follow pediatric guidance and monitor growth.
  • Avoid concomitant nasal decongestants to reduce irritation.
  • Do not exceed the recommended duration without medical advice.
  • Store at room temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Mometasone furoate may interact with other medicines; monitor as indicated.

Major Interactions (Avoid)

  • Systemic corticosteroids: increased risk of systemic glucocorticoid effects.
  • Strong CYP3A4 inhibitors: may raise local drug exposure.

Moderate Interactions (Monitor Closely)

  • Antihistamines: may enhance sedation, though effect is minimal.
  • Nasal antibiotics: could increase local irritation.
  • Live nasal vaccines: efficacy may be reduced.

Frequently Asked Questions

Mometasone Furoate Monohydrate Aurobindo is a nasal corticosteroid indicated for the treatment of allergic rhinitis, including both seasonal and perennial forms. It helps relieve nasal congestion, sneezing, itching, and runny nose by reducing inflammation of the nasal passages.

Mometasone furoate works by binding to intracellular glucocorticoid receptors in nasal mucosal cells. This complex alters gene transcription, leading to decreased production of inflammatory mediators such as cytokines and prostaglandins, which in turn reduces swelling, mucus production, and allergic symptoms.

The prescribed dose is determined by the treating clinician based on the patient’s age, severity of symptoms, and response to therapy. Typical regimens involve one or two sprays per nostril once daily, but exact dosing should always follow the healthcare professional’s instructions.

Safety data for mometasone furoate in pregnancy and lactation are limited. It should be used only if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made in consultation with a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Mometasone furoate is a high‑potency intranasal corticosteroid with a low systemic bioavailability, similar to fluticasone propionate and budesonide. Compared with some alternatives, it may offer longer symptom control with once‑daily dosing, but clinical choice depends on individual response, tolerability, and physician preference.

Store the nasal spray at room temperature, preferably below 25 °C. Keep it in the original packaging to protect from moisture and direct sunlight. Do not freeze the product, and ensure the cap is tightly closed when not in use.

The medication is delivered as a nasal spray. Before use, gently shake the bottle, prime it if required, and tilt the head slightly forward. Insert the nozzle into one nostril, close the opposite nostril, and spray the prescribed number of sprays while breathing in gently. Repeat in the other nostril if directed.

Serious but rare risks include nasal septal perforation, severe allergic reactions such as anaphylaxis, and systemic effects like adrenal suppression when used for extended periods. Patients should seek immediate medical attention if they experience unusual nosebleeds, persistent pain, or signs of an allergic reaction.

Individuals with known hypersensitivity to mometasone furoate or any component of the formulation should avoid its use. It is also contraindicated in patients with active untreated fungal, bacterial, or viral infections of the nasal passages until the infection is resolved.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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