Product image of Mometasone Furoate/Olopatadine Glenmark (Mometasone Furoate, Olopatadine) supplied by GNH India

Mometasone Furoate/Olopatadine Glenmark

Active Ingredient:
Mometasone Furoate, Olopatadine
Origin:
EU

Mometasone Furoate/Olopatadine Glenmark (Mometasone Furoate, Olopatadine)

Mometasone furoate and olopatadine, the active ingredients in Mometasone Furoate/Olopatadine Glenmark, are a corticosteroid/antihistamine combination presented as a nasal spray for nasal use. It treats allergic rhinitis, including seasonal and perennial forms, by reducing nasal inflammation and congestion.

GNH India supplies Mometasone Furoate/Olopatadine Glenmark as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Glenmark Arzneimittel Gmbh

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Indications & Clinical Uses

Mometasone furoate/olopatadine is used to manage allergic rhinitis and related nasal inflammation.

  • Seasonal allergic rhinitis: relieves sneezing, itching, rhinorrhea and nasal blockage caused by seasonal allergens.
  • Perennial allergic rhinitis: controls chronic nasal symptoms triggered by year‑round allergens.
  • Nasal congestion due to allergic inflammation: improves airflow and reduces swelling of nasal passages.

How It Works

  • Mometasone furoate activates glucocorticoid receptors, suppressing cytokine production and inflammatory cell migration, while olopatadine selectively blocks H1 histamine receptors and stabilises mast cells, preventing release of histamine and other mediators. The combined actions reduce nasal mucosal edema, secretions and allergic symptom intensity.

Side Effects

Adverse reactions may occur with intranasal use of this corticosteroid/antihistamine combination.

Common Side Effects

  • Nasal irritation or burning sensation
  • Headache
  • Altered taste or bitter taste
  • Epistaxis (nosebleed)
  • Throat irritation
  • Cough

Serious or Rare Side Effects

  • Adrenal suppression with prolonged high‑dose use
  • Anaphylactic or severe allergic reaction
  • Vision changes or increased intraocular pressure
  • Nasal septum perforation
  • Opportunistic fungal infection of the nasal cavity
  • Severe local infection or ulceration

Precautions & Warnings

Before using this nasal spray, consider the following safety measures.

  • Pregnancy: consult a healthcare professional; data are limited.
  • Breastfeeding: discuss potential risks with a clinician.
  • Existing nasal infections: treat infection before initiating therapy.
  • Concurrent systemic steroids: monitor for additive corticosteroid effects.
  • Children under 12 years: use only if prescribed by a qualified practitioner.
  • Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Mometasone furoate/olopatadine may interact with other medicines; awareness helps avoid complications.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): may increase systemic corticosteroid exposure.
  • Systemic corticosteroids: risk of additive glucocorticoid effects.
  • Live vaccines: potential reduced vaccine efficacy.

Moderate Interactions (Monitor Closely)

  • Other intranasal decongestants or antihistamines: may increase local irritation.
  • Immunosuppressants: monitor for infection risk.
  • Antifungal agents used nasally: assess for overlapping side‑effects.

Frequently Asked Questions

Mometasone Furoate/Olopatadine Glenmark is indicated for the treatment of allergic rhinitis, both seasonal and perennial, and for relieving nasal congestion caused by allergic inflammation. It combines a corticosteroid and an antihistamine to address inflammation and histamine‑mediated symptoms in the nasal passages.

Mometasone furoate binds to glucocorticoid receptors in nasal mucosal cells, leading to reduced production of inflammatory cytokines and decreased infiltration of inflammatory cells. This anti‑inflammatory action helps to shrink swollen nasal tissue and lower mucus production.

The specific dosing regimen for Mometasone Furoate/Olopatadine is determined by the prescribing clinician based on the patient’s age, severity of symptoms, and overall health status. Patients should follow the prescriber’s instructions and the product label.

Safety data for use during pregnancy and lactation are limited. Healthcare providers should evaluate the potential benefits against any possible risks before prescribing this medication to pregnant or nursing individuals.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with single‑agent antihistamine sprays, the Mometasone Furoate/Olopatadine combo offers both anti‑inflammatory and antihistaminic effects, potentially providing more comprehensive symptom control. Unlike oral antihistamines, the nasal route delivers medication directly to the site of inflammation, reducing systemic exposure.

Store the nasal spray at ambient temperature, preferably below 25 °C. Keep the device in its original packaging, protect it from moisture and direct sunlight, and ensure the cap is tightly closed when not in use.

The product is administered as a nasal spray. The patient should gently blow the nose, tilt the head slightly forward, insert the nozzle into one nostril, and spray the prescribed number of sprays while breathing in gently. The procedure is repeated in the other nostril if directed by the prescriber.

Serious risks, though rare, include adrenal suppression with prolonged high‑dose use, severe allergic reactions such as anaphylaxis, nasal septum perforation, and opportunistic fungal infections of the nasal cavity. Patients should seek immediate medical attention if they experience symptoms like severe nosebleeds, vision changes, or signs of systemic infection.

Individuals with known hypersensitivity to mometasone furoate, olopatadine, or any component of the formulation should avoid this product. It is also contraindicated in patients with active untreated nasal infections or recent nasal surgery unless specifically advised by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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