Product image of Mometasone Furoate Sandoz Ltd (Mometasone Furoate) supplied by GNH India

Mometasone Furoate Sandoz Ltd

Active Ingredient:
Mometasone Furoate
Origin:
EU

Mometasone Furoate Sandoz Ltd (Mometasone Furoate)

Mometasone furoate, the active ingredient in Mometasone Furoate Sandoz Ltd, is a corticosteroid presented as a nasal spray for nasal use. It treats allergic rhinitis, seasonal and perennial forms, and nasal polyps in adults and children as prescribed.

GNH India supplies Mometasone Furoate Sandoz Ltd as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Sandoz Ltd

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Indications & Clinical Uses

Mometasone furoate nasal spray acts on inflammatory processes of the nasal mucosa to relieve allergic conditions.

  • Allergic rhinitis: reduces nasal congestion, sneezing and itching.
  • Seasonal allergic rhinitis: provides symptom control during pollen seasons.
  • Perennial allergic rhinitis: alleviates year‑round nasal inflammation.
  • Nasal polyps: helps shrink polyps and improves airflow.

How It Works

  • Mometasone furoate binds to intracellular glucocorticoid receptors in nasal epithelial cells, altering gene transcription. This down‑regulates pro‑inflammatory cytokines, chemokines and adhesion molecules, leading to decreased inflammatory cell infiltration and reduced edema of the nasal mucosa.

Side Effects

Mometasone furoate nasal spray may cause local and systemic adverse reactions.

Common Side Effects

  • Nasal irritation: burning or stinging sensation.
  • Headache: mild to moderate intensity.
  • Epistaxis: occasional nosebleeds.
  • Throat irritation: soreness or dryness.
  • Cough: transient irritation.
  • Altered taste: temporary dysgeusia.

Serious or Rare Side Effects

  • Nasal septal perforation: loss of tissue integrity.
  • Severe allergic reaction: anaphylaxis signs.
  • Vision changes: blurred vision or cataract formation.
  • Adrenal suppression: signs of systemic glucocorticoid effect.
  • Secondary infection: fungal or bacterial overgrowth.
  • Elevated intra‑ocular pressure: glaucoma risk.

Precautions & Warnings

Before using Mometasone Furoate nasal spray, consider the following precautions.

  • Pregnancy: consult a healthcare provider before initiating therapy.
  • Breastfeeding: discuss potential risks with a physician.
  • Nasal surgery or trauma: postpone use until the nasal mucosa has healed.
  • Long‑term use: monitor for signs of adrenal suppression or ocular effects.
  • Pediatric use: follow pediatric dosing recommendations.
  • Store at room temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Mometasone furoate nasal spray can interact with other medicines; review the following categories.

Major Interactions (Avoid)

  • Systemic corticosteroids: increased risk of systemic glucocorticoid effects.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole): may raise local drug exposure.

Moderate Interactions (Monitor Closely)

  • Antihistamines: additive symptom control, monitor for excessive sedation.
  • Nasal decongestants: potential for increased local irritation.
  • Live vaccines: consider timing of administration relative to steroid use.

Frequently Asked Questions

Mometasone Furoate Sandoz Ltd is a prescription nasal spray indicated for the treatment of allergic rhinitis—including seasonal and perennial forms—as well as for reducing the size of nasal polyps. It works by decreasing inflammation in the nasal passages, helping to relieve congestion, sneezing, itching, and nasal obstruction.

Mometasone furoate is a potent glucocorticoid that binds to intracellular glucocorticoid receptors in nasal mucosal cells. This binding modifies gene transcription, leading to reduced production of inflammatory cytokines, chemokines, and adhesion molecules, which in turn diminishes inflammatory cell infiltration and edema in the nasal lining.

The specific dosing regimen for Mometasone Furoate nasal spray is determined by the prescribing healthcare professional based on the patient’s age, severity of symptoms, and clinical response. Typically, the label recommends one spray per nostril once daily, but the exact dose and frequency should follow the prescriber’s instructions.

Safety data for mometasone furoate in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using the product.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide. After submission, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details (including any cold‑chain requirements), and assist with import documentation.

Both mometasone furoate and fluticasone are intranasal corticosteroids with similar anti‑inflammatory mechanisms. Mometasone is often noted for its high receptor affinity and once‑daily dosing, while fluticasone may have a slightly different safety profile regarding systemic absorption. Clinical choice depends on physician preference, patient response, and formulary considerations.

Store the nasal spray at room temperature, away from direct sunlight and moisture. Keep the product in its original packaging until use, and ensure the cap is tightly closed after each application to maintain sterility and potency.

Before first use, prime the spray by actuating it a few times until a fine mist appears. Gently blow the nose, tilt the head slightly forward, insert the tip into one nostril, close the opposite nostril with a finger, and press the pump while breathing in gently through the nose. Repeat in the other nostril if prescribed.

Serious adverse events, though rare, include nasal septal perforation, severe allergic reactions such as anaphylaxis, adrenal suppression leading to systemic glucocorticoid effects, and ocular complications like increased intra‑ocular pressure or cataract formation. Patients should seek immediate medical attention if they experience any of these symptoms.

The spray should be avoided in individuals with known hypersensitivity to mometasone furoate or any component of the formulation. It is also contraindicated in patients with active untreated fungal, bacterial, or viral infections of the nasal passages, and in those who have recently undergone nasal surgery until healing is complete.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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