Mometasone Teva (Mometasone Furoate)

Mometasone Teva is a corticosteroid nasal spray that targets inflammatory processes in the upper airway, primarily used for allergic conditions.

• Seasonal allergic rhinitis: relieves sneezing, nasal itching and congestion during pollen seasons.
• Perennial allergic rhinitis: controls year‑round symptoms caused by indoor allergens.
• Allergic rhinitis (overall): reduces nasal inflammation and improves airflow for patients of all ages.

• Mometasone furoate binds to intracellular glucocorticoid receptors, forming a complex that translocates to the nucleus and modulates gene transcription. This action suppresses the production of pro‑inflammatory cytokines, chemokines, and other mediators, leading to decreased vascular permeability and reduced inflammatory cell infiltration in the nasal mucosa.

Mometasone Teva may cause local and systemic adverse reactions, most of which are mild and reversible.

Common Side Effects

• Nasal irritation or burning sensation.
• Epistaxis (nosebleeds).
• Headache.
• Throat irritation.
• Cough.
• Unpleasant taste.

Serious or Rare Side Effects

• Nasal septal perforation.
• Secondary infections such as fungal sinusitis.
• Elevated intra‑ocular pressure or glaucoma.
• Adrenal suppression with prolonged high‑dose use.
• Systemic corticosteroid effects (e.g., hyperglycemia) in susceptible individuals.
• Allergic reactions including rash or angioedema.

Before using Mometasone Teva, consider the following safety measures.

• Assess infection risk: avoid use if active nasal or sinus infection is present.
• Monitor for ocular effects: patients with glaucoma or cataracts should be evaluated regularly.
• Evaluate systemic exposure: prolonged high‑dose therapy may affect adrenal function.
• Pregnancy and lactation: use only if the potential benefit justifies the potential risk.
• Pediatric use: follow pediatric dosing guidelines provided by the prescriber.
• Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Mometasone Teva can interact with other medications that influence corticosteroid metabolism or increase infection risk.

Major Interactions (Avoid)

• Systemic CYP3A4 inhibitors (e.g., ketoconazole) that may increase systemic exposure.
• Live vaccines: concurrent use may reduce vaccine efficacy.

Moderate Interactions (Monitor Closely)

• Other intranasal corticosteroids: may increase local side effects.
• Antifungal agents (e.g., itraconazole) that affect steroid clearance.
• Immunosuppressants: heightened risk of infections.
• Nasal decongestants: may mask signs of worsening inflammation.
• Antihistamines: monitor for additive sedation if combined with sedating antihistamines.