Product image of Mometasonfuroat Al (Mometasone Furoate Ph. Eur.) supplied by GNH India

Mometasonfuroat Al

Active Ingredient:
Mometasone Furoate Ph. Eur.
Origin:
EU

Mometasonfuroat Al (Mometasone Furoate Ph. Eur.)

Mometasone furoate, the active ingredient in Mometasonfuroat Al, is a corticosteroid presented as a nasal formulation for nasal use. It treats allergic rhinitis and nasal polyps in adults and children.

GNH India supplies Mometasonfuroat Al as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Aliud Pharma Gmbh

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Indications & Clinical Uses

Mometasone furoate is a topical corticosteroid used to manage inflammatory conditions of the nasal passages.

  • Allergic rhinitis: reduces nasal congestion, itching and sneezing.
  • Nasal polyps: decreases polyp size and improves nasal airflow.
  • Seasonal allergic rhinitis: alleviates symptoms during pollen seasons.

How It Works

  • Mometasone furoate binds to intracellular glucocorticoid receptors in nasal mucosal cells, altering gene transcription. This down‑regulates the production of pro‑inflammatory cytokines, chemokines and adhesion molecules, leading to reduced recruitment and activation of inflammatory cells and decreased edema of the nasal lining.

Side Effects

Adverse reactions may occur with nasal administration of mometasone furoate.

Common Side Effects

  • Nasal irritation or burning sensation.
  • Epistaxis (nosebleeds).
  • Headache.
  • Altered taste or bitter taste.
  • Throat irritation.
  • Dryness of the nasal mucosa.

Serious or Rare Side Effects

  • Fungal infection of the nasal passages.
  • Severe or prolonged nosebleeds.
  • Vision changes such as cataracts or glaucoma.
  • Adrenal suppression with systemic absorption.
  • Anaphylactic or severe allergic reactions.
  • Nasal septum perforation (rare).

Precautions & Warnings

Use of Mometasonfuroat Al requires careful consideration of several safety aspects.

  • Prescription only: use under medical supervision.
  • Hypersensitivity: avoid if known allergy to mometasone or other corticosteroids.
  • Recent nasal surgery or trauma: postpone use until healing is complete.
  • Long‑term use: monitor for signs of adrenal suppression or mucosal atrophy.
  • Concomitant systemic steroids: assess risk of additive corticosteroid effects.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Mometasone furoate may interact with other medicines that affect corticosteroid metabolism or immune response.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole) – may increase systemic exposure.
  • Live intranasal vaccines – reduced efficacy when used concurrently.

Moderate Interactions (Monitor Closely)

  • Antifungal agents (e.g., fluconazole) – possible modest increase in exposure.
  • HIV protease inhibitors – may elevate corticosteroid levels.
  • Systemic corticosteroids – additive immunosuppressive effect.
  • Antihistamines – may mask early signs of local irritation.

Frequently Asked Questions

Mometasonfuroat Al contains mometasone furoate, a nasal corticosteroid indicated for the treatment of allergic rhinitis and for reducing the size of nasal polyps. It helps relieve nasal congestion, itching, sneezing and improves airflow in affected patients.

Mometasone furoate binds to glucocorticoid receptors in the cells lining the nasal passages. This interaction modifies gene expression, suppressing the release of inflammatory mediators such as cytokines and prostaglandins, which reduces swelling and irritation of the nasal mucosa.

The specific dosing regimen for Mometasonfuroat Al is determined by the prescribing healthcare professional based on the patient’s age, severity of symptoms and clinical response. Patients should follow the prescriber’s instructions and the product label.

Safety data for mometasone furoate in pregnancy and lactation are limited. The product should only be used if the potential benefit justifies any possible risk to the fetus or infant, and this decision must be made by the treating physician.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Mometasone furoate is a high‑potency intranasal corticosteroid with a favorable safety profile when used as directed. Compared with older agents such as beclomethasone, it offers once‑daily dosing and a lower risk of systemic absorption, making it a preferred option for many clinicians.

Store Mometasonfuroat Al at room temperature, below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed when not in use.

Mometasonfuroat Al is administered as a nasal spray. The patient should gently blow the nose, insert the nozzle into one nostril, and spray the prescribed number of sprays while breathing in gently. The same procedure is repeated in the other nostril if required.

Serious risks, although rare, include fungal infections of the nasal mucosa, severe nosebleeds, adrenal suppression, cataracts or glaucoma, and anaphylactic reactions. Patients should seek immediate medical attention if they experience unusual bleeding, visual changes or signs of an allergic reaction.

Mometasonfuroat Al should be avoided in individuals with known hypersensitivity to mometasone furoate or any component of the formulation. It is also contraindicated in patients with active untreated fungal infections of the nasal passages and should be used with caution after recent nasal surgery.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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