Product image of Monkasta (Montelukast) supplied by GNH India

Monkasta

Active Ingredient:
Montelukast
Origin:
EU

Monkasta (Montelukast)

Montelukast, the active ingredient in Monkasta, is a leukotriene receptor antagonist presented as an oral tablet for oral use. It treats asthma, allergic rhinitis and exercise‑induced bronchoconstriction in patients requiring controller therapy.
GNH India supplies Monkasta as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Krka, D.D., Novo Mesto

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Indications & Clinical Uses

  • Montelukast acts on leukotriene pathways to manage respiratory and allergic conditions.
  • Asthma: Improves control of chronic airway inflammation and reduces frequency of exacerbations.
  • Allergic rhinitis: Alleviates nasal congestion, sneezing and itching associated with seasonal allergies.
  • Exercise‑induced bronchoconstriction: Prevents narrowing of airways triggered by physical activity.

How It Works

  • Montelukast selectively blocks the cysteinyl leukotriene receptor CysLT1, preventing leukotriene D4 from binding. This inhibition reduces leukotriene‑mediated bronchoconstriction, vascular permeability, and inflammatory cell recruitment in the airways, thereby improving respiratory function and decreasing allergic inflammation.

Side Effects

Montelukast may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Headache: mild to moderate pain in the head.
  • Abdominal pain: discomfort or cramping in the stomach area.
  • Nausea: feeling of sickness or urge to vomit.
  • Upper respiratory infection: symptoms such as sore throat, cough or congestion.

Serious or Rare Side Effects

  • Allergic reactions: rash, itching, swelling, or severe anaphylaxis.
  • Mood changes: depression, anxiety, or suicidal thoughts.
  • Liver enzyme elevation: abnormal liver function test results.

Precautions & Warnings

  • Before initiating therapy, consider the following safety measures.
  • Pregnancy: safety not established; discuss risks with healthcare provider.
  • Breastfeeding: unknown; weigh benefits against potential risks.
  • Hepatic impairment: use with caution; monitor liver function.
  • Concomitant asthma therapy: may need to continue other controller medications.
  • Store at ambient temperature below 25°C: keep in original packaging, protect from moisture.

Avoid Interactions

Montelukast can interact with several medicines; monitoring is advised.

Major Interactions (Avoid)

  • Ritonavir: may increase montelukast plasma concentrations.
  • Phenobarbital: may reduce montelukast effectiveness.

Moderate Interactions (Monitor Closely)

  • Fluconazole: may modestly increase exposure.
  • Carbamazepine: may decrease montelukast levels.
  • Warfarin: monitor INR as montelukast may affect anticoagulation.

Frequently Asked Questions

Monkasta contains montelukast, which is prescribed to manage chronic asthma, relieve symptoms of allergic rhinitis, and prevent exercise‑induced bronchoconstriction. It is used in patients who need a leukotriene‑targeted approach to control airway inflammation and allergy‑related nasal symptoms.

Montelukast blocks the CysLT1 receptor, preventing cysteinyl leukotrienes from binding. By inhibiting these inflammatory mediators, it reduces bronchoconstriction, mucus production, and vascular leakage in the airways, leading to improved breathing and reduced allergic inflammation.

The specific dose of Monkasta is determined by the prescribing healthcare professional based on the patient’s age, condition severity, and response to therapy. Dosage instructions are provided on the prescription label and should be followed exactly as directed.

Safety data for montelukast in pregnancy and lactation are limited. The prescriber should evaluate the potential benefits against any possible risks before prescribing Monkasta to pregnant or nursing individuals. Consultation with a healthcare provider is essential.

To request Monkasta, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Monkasta (montelukast) belongs to the leukotriene receptor antagonist class, offering an oral alternative to inhaled corticosteroids or long‑acting beta‑agonists. It is particularly useful for patients with aspirin‑sensitive asthma or those who prefer a once‑daily tablet, but it may be used alongside other controller medications for optimal control.

Monkasta should be stored at ambient temperature below 25 °C. Keep the tablets in the original container, protect them from moisture and direct sunlight, and ensure they are out of reach of children.

Monkasta is taken orally, usually once daily in the evening, with or without food, as directed by the prescriber. Swallow the tablet whole; do not crush, chew, or split it unless specifically instructed.

Serious adverse events, although rare, can include severe allergic reactions such as rash, swelling or anaphylaxis, as well as mood changes like depression, anxiety, or suicidal thoughts. Liver enzyme elevations have also been reported; patients should report any unusual symptoms promptly.

Monkasta is contraindicated in individuals with known hypersensitivity to montelukast or any of the tablet’s excipients. Patients with uncontrolled severe liver disease should avoid use, and it should be prescribed with caution in those with a history of psychiatric disorders.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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