Product image of Monoprost (Latanoprost) supplied by GNH India

Monoprost

Active Ingredient:
Latanoprost
Origin:
EU

Monoprost (Latanoprost)

Latanoprost, the active ingredient in Monoprost, is a prostaglandin analog presented as an ophthalmic solution for ocular use. It is employed to lower intra‑ocular pressure in adult and elderly patients with primary open‑angle glaucoma or ocular hypertension, helping to preserve visual function.

GNH India supplies Monoprost as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides full regulatory documentation to support global distribution and clinical use through reliable supply chains.

Manufacturer / TM Owner

Laboratoires Thea

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Indications & Clinical Uses

Latanoprost is a prostaglandin analog used to manage ocular pressure in glaucoma and ocular hypertension.

  • Primary open‑angle glaucoma: reduces intra‑ocular pressure to slow disease progression.
  • Ocular hypertension: lowers eye pressure to prevent conversion to glaucoma.
  • Pseudoexfoliative glaucoma: helps control intra‑ocular pressure in this secondary form of open‑angle glaucoma.

How It Works

  • Latanoprost binds to prostaglandin F (FP) receptors in the ciliary body, enhancing uveoscleral outflow of aqueous humor. This increased outflow reduces intra‑ocular pressure, thereby helping to protect the optic nerve from pressure‑related damage.

Side Effects

Latanoprost may cause ocular and systemic reactions.

Common Side Effects

  • Eye redness: mild conjunctival hyperemia.
  • Increased eyelash growth: longer, thicker lashes.
  • Iris pigmentation: gradual darkening of eye colour.
  • Eye irritation: foreign‑body sensation or mild discomfort.
  • Blurred vision: temporary visual disturbance after instillation.
  • Periorbital skin darkening: mild hyperpigmentation of surrounding skin.

Serious or Rare Side Effects

  • Severe allergic reaction: swelling, rash, or difficulty breathing.
  • Uveitis: inflammation inside the eye requiring urgent care.
  • Macular edema: fluid accumulation in the central retina.
  • Ocular infection: signs of bacterial or fungal infection.
  • Vision loss: sudden decrease in visual acuity.
  • Persistent hypotony: excessively low intra‑ocular pressure.

Precautions & Warnings

When prescribing or using Monoprost, consider the following precautions.

  • Monitor IOP: regular intra‑ocular pressure measurements are essential.
  • Assess for ocular inflammation: avoid use in active eye infections or uveitis.
  • Caution with contact lens wearers: may cause lens deposits.
  • Pregnancy and lactation: safety not established; consult a physician.
  • History of ocular surgery: evaluate risk of delayed healing.
  • Store at room temperature: keep bottle tightly closed, protect from light and moisture.

Avoid Interactions

Latanoprost may interact with other ocular or systemic agents.

Major Interactions (Avoid)

  • Concomitant prostaglandin analogs: additive IOP lowering may cause hypotony.
  • Non‑steroidal anti‑inflammatory eye drops: may reduce latanoprost efficacy.
  • Systemic carbonic anhydrase inhibitors: increased risk of ocular side effects.

Moderate Interactions (Monitor Closely)

  • Beta‑blocker eye drops: additive IOP reduction requires monitoring.
  • Alpha‑agonist eye drops: combined effect on pressure may need adjustment.
  • Topical corticosteroids: may diminish IOP‑lowering effect of latanoprost.

Frequently Asked Questions

Monoprost contains latanoprost, a prostaglandin analog prescribed to lower intra‑ocular pressure in patients with primary open‑angle glaucoma or ocular hypertension, helping to protect the optic nerve and preserve vision.

Latanoprost activates prostaglandin F (FP) receptors in the eye, increasing uveoscleral outflow of aqueous humor. This enhanced drainage reduces intra‑ocular pressure, which is the primary therapeutic goal in glaucoma management.

The dosing regimen for Monoprost is determined by the prescribing clinician. Typically, a single drop is instilled in the affected eye(s) once daily in the evening, but the exact schedule should follow the prescriber’s instructions.

Safety data for latanoprost in pregnancy and lactation are limited. It should be used only if the potential benefit justifies the potential risk, and the decision should be made in consultation with a healthcare professional.

To request Monoprost, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Latanoprost is often preferred over beta‑blocker eye drops such as timolol because it requires once‑daily dosing and has a favorable side‑effect profile. Compared with other prostaglandin analogs (e.g., bimatoprost), efficacy is similar, though individual tolerability may vary.

Monoprost should be stored at room temperature, below 25 °C, in its original container. Keep the bottle tightly closed, protect it from light and moisture, and discard any solution that appears discolored or contaminated.

Monoprost is applied as an ophthalmic solution. The patient should wash hands, tilt the head back, pull down the lower eyelid, place one drop into the conjunctival sac, and close the eye gently for a few minutes without blinking excessively.

Serious risks include severe allergic reactions, uveitis, macular edema, ocular infection, and persistent hypotony leading to vision loss. Patients should seek immediate medical attention if they experience sudden eye pain, redness, vision changes, or systemic allergic symptoms.

Monoprost is contraindicated in patients with known hypersensitivity to latanoprost or any component of the formulation, active ocular infections, or severe inflammation. Caution is advised for individuals with a history of uveitis, recent ocular surgery, or uncontrolled systemic conditions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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