Product image of Monoprost (Latanoprost) supplied by GNH India

Monoprost

Active Ingredient:
Latanoprost
Origin:
EU

Monoprost (Latanoprost)

Latanoprost, the active ingredient in Monoprost, is a prostaglandin analog presented as eye drops for ocular use. It lowers intra‑ocular pressure and is indicated for the management of open‑angle glaucoma and ocular hypertension in adult patients.

GNH India supplies Monoprost as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, adhering to stringent quality standards and providing regulatory‑approved products to meet the needs of eye‑care professionals across multiple regions.

Manufacturer / TM Owner

Laboratoires Thea

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Indications & Clinical Uses

  • Monoprost (latanoprost) is a prostaglandin analog used to reduce intra‑ocular pressure in glaucoma‑related conditions.
  • Open-angle glaucoma: reduces intra‑ocular pressure to slow disease progression.
  • Ocular hypertension: lowers pressure to prevent conversion to glaucoma.
  • Secondary open-angle glaucoma: decreases pressure when other causes elevate intra‑ocular pressure.

How It Works

  • Latanoprost binds to prostaglandin F (FP) receptors in the ciliary muscle, promoting remodeling of the extracellular matrix and increasing uveoscleral outflow of aqueous humor. This enhanced outflow lowers intra‑ocular pressure, helping to control glaucoma and ocular hypertension.

Side Effects

Common Side Effects

  • Eye redness or hyperemia.
  • Increased eyelash growth.
  • Darkening of the iris pigment.
  • Mild eye irritation or foreign‑body sensation.
  • Blurred vision.
  • Temporary eye discomfort.

Serious or Rare Side Effects

  • Severe allergic reaction (e.g., swelling, rash).
  • Uveitis or intra‑ocular inflammation.
  • Corneal edema or swelling.
  • Paradoxical increase in intra‑ocular pressure.
  • Vision loss.
  • Persistent eye pain.

Precautions & Warnings

Before using Monoprost, consider the following precautions:

  • Monitor intra‑ocular pressure regularly during treatment.
  • Avoid use in eyes with active infection or inflammation.
  • Use with caution in patients with a history of uveitis.
  • Advise patients not to wear contact lenses while using the drops.
  • Discuss pregnancy or breastfeeding status with the prescriber.
  • Store at room temperature: keep the bottle in the original packaging, protect from light and avoid freezing.

Avoid Interactions

Monoprost may interact with other ocular medications. Review the following:

Major Interactions (Avoid)

  • Concurrent use of other prostaglandin analog eye drops.
  • Simultaneous administration of ocular anesthetics that may increase irritation.

Moderate Interactions (Monitor Closely):\n- Beta‑blocker eye drops (additive IOP‑lowering effect).

  • Alpha‑agonist eye drops (potential additive pressure reduction).
  • Topical corticosteroids (may diminish prostaglandin efficacy).
  • Systemic antihistamines (possible impact on tear production).
  • Ocular lubricants (generally safe but monitor for discomfort).

Frequently Asked Questions

Monoprost contains latanoprost, a prostaglandin analog prescribed to lower intra‑ocular pressure in patients with open‑angle glaucoma or ocular hypertension, helping to prevent optic nerve damage and preserve vision.

Latanoprost activates prostaglandin F receptors in the eye, which remodels the extracellular matrix of the ciliary body and increases uveoscleral outflow of aqueous humor, thereby reducing intra‑ocular pressure.

The dosing regimen for Monoprost is determined by the prescribing ophthalmologist. Typically, one drop is instilled in the affected eye(s) once daily in the evening, but the exact dose and schedule must follow the prescriber’s instructions.

The safety of latanoprost in pregnancy or lactation has not been definitively established. Healthcare providers should weigh potential benefits against risks and consider alternative treatments if pregnancy or breastfeeding is planned or ongoing.

To order Monoprost, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Monoprost belongs to the prostaglandin analog class, which generally offers once‑daily dosing and strong intra‑ocular pressure reduction. Compared with beta‑blocker or carbonic anhydrase inhibitor drops, prostaglandin analogs often have a more convenient dosing schedule but may cause distinct ocular side effects such as iris darkening.

Monoprost eye drops should be stored at room temperature, protected from light and moisture. Keep the bottle tightly closed, store in the original packaging, and avoid freezing. Discard any solution that appears discolored or contains particles.

Monoprost is applied as a single drop to the conjunctival sac of the affected eye(s) once daily, usually in the evening. The patient should tilt the head back, pull down the lower eyelid, instill the drop, and close the eye gently without rubbing.

Serious risks include severe allergic reactions, uveitis, corneal edema, paradoxical rise in intra‑ocular pressure, and vision loss. Patients should seek immediate medical attention if they experience intense eye pain, sudden vision changes, or signs of an allergic response.

Monoprost should be avoided in patients with active ocular infections, severe inflammation, known hypersensitivity to latanoprost or any component of the formulation, and in individuals where the prescriber determines the risks outweigh the benefits.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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