Product image of Monoprost (Latanoprost) supplied by GNH India

Monoprost

Active Ingredient:
Latanoprost
Origin:
EU

Monoprost (Latanoprost)

Latanoprost, the active ingredient in Monoprost, is a prostaglandin analog presented as an ophthalmic solution for ocular use. It is employed to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension.
GNH India supplies Monoprost as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratoires Thea

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Indications & Clinical Uses

  • Monoprost is a prostaglandin analog indicated for conditions that require reduction of intraocular pressure.
  • Open-angle glaucoma: lowers intraocular pressure to help preserve visual field and prevent optic nerve damage.
  • Ocular hypertension: reduces elevated eye pressure to decrease the risk of developing glaucoma.

How It Works

  • Latanoprost binds to prostaglandin F (FP) receptors in the ciliary muscle, promoting remodeling of the extracellular matrix and increasing uveoscleral outflow of aqueous humor. This enhanced drainage lowers intraocular pressure, thereby mitigating the progression of glaucomatous optic neuropathy.

Side Effects

Latanoprost may cause ocular and systemic reactions, most of which are mild and transient.

Common Side Effects

  • Eye irritation or burning sensation after instillation.
  • Conjunctival hyperemia (eye redness).
  • Increased eyelash growth and length.
  • Darkening of the iris color over time.
  • Transient blurred vision.

Serious or Rare Side Effects

  • Uveitis or severe intraocular inflammation.
  • Allergic reactions such as swelling of the eyelid or face.
  • Persistent ocular pain or visual disturbances.
  • Corneal edema or keratitis.
  • Rare cases of macular edema.

Precautions & Warnings

  • Patients should be counseled on proper use and monitored for ocular changes.
  • Monitor intraocular pressure: ensure therapeutic target is achieved.
  • Assess for ocular infections: avoid use if active infection is present.
  • Avoid use in patients with active ocular inflammation: may exacerbate condition.
  • Inform patients about possible iris color change: irreversible darkening may occur.
  • Store at room temperature: keep bottle tightly closed, protect from light and freezing.

Avoid Interactions

Latanoprost may interact with other ocular or systemic agents, requiring vigilance.

Major Interactions (Avoid)

  • Concomitant use with other prostaglandin analogs: may increase risk of ocular side effects.
  • Use with ocular anesthetics: can heighten corneal toxicity.

Moderate Interactions (Monitor Closely)

  • Combined therapy with carbonic anhydrase inhibitors: additive intraocular pressure reduction, monitor pressure.
  • Non‑steroidal anti‑inflammatory eye drops: may alter drug absorption.
  • Systemic beta‑blockers: potential for enhanced hypotensive effect, observe systemic blood pressure.

Frequently Asked Questions

Monoprost contains latanoprost, a prostaglandin analog prescribed to lower intraocular pressure in adults with open-angle glaucoma or ocular hypertension, helping to prevent optic nerve damage and preserve vision.

Latanoprost activates prostaglandin F receptors in the ciliary body, remodeling extracellular matrix and enhancing uveoscleral outflow of aqueous humor, which reduces intraocular pressure and slows glaucoma progression.

The dosing regimen for Monoprost is determined by the prescribing clinician. Typically, one drop is instilled into the affected eye(s) once daily in the evening, but exact instructions must follow the prescriber’s order.

The safety of latanoprost in pregnancy and lactation has not been established. It should be used only if the potential benefit justifies the potential risk to the fetus or infant, and the prescriber should evaluate each case individually.

To request Monoprost, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and necessary import documentation.

Monoprost belongs to the prostaglandin analog class, which generally offers once‑daily dosing and strong intraocular pressure reduction. Compared with beta‑blocker drops, prostaglandin analogs often have a more favorable dosing schedule and fewer systemic side effects, though they may cause ocular changes such as iris darkening.

Monoprost should be stored at room temperature, below 25 °C, in its original container. Keep the bottle tightly closed, protect it from light, and avoid freezing. Do not refrigerate unless specifically instructed by the supplier.

Monoprost is applied as a single ophthalmic drop to the affected eye(s) once daily, usually in the evening. The patient should wash hands, avoid touching the tip of the bottle to the eye or any surface, and gently close the eye after instillation.

Serious risks include uveitis or severe intraocular inflammation, allergic reactions such as eyelid swelling, and rare cases of macular edema. Patients should report any sudden eye pain, vision changes, or signs of infection to their eye care professional promptly.

Monoprost is contraindicated in patients with active ocular infections or inflammation, hypersensitivity to latanoprost or any component of the formulation, and should be used with caution in individuals with a history of severe ocular inflammation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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