Product image of Monoprost (Latanoprost) supplied by GNH India

Monoprost

Active Ingredient:
Latanoprost
Origin:
EU

Monoprost (Latanoprost)

Latanoprost, the active ingredient in Monoprost, is a prostaglandin analog presented as an ophthalmic solution for ocular use. It lowers intra‑ocular pressure and is indicated for open‑angle glaucoma and ocular hypertension in adult patients.

GNH India supplies Monoprost as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratoires Thea

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Indications & Clinical Uses

Monoprost belongs to the prostaglandin analog class and is used to manage conditions that involve elevated intra‑ocular pressure.

  • Open‑angle glaucoma: reduces intra‑ocular pressure to slow disease progression.
  • Ocular hypertension: lowers intra‑ocular pressure to prevent development of glaucoma.
  • Elevated intra‑ocular pressure (any cause): helps maintain target pressure and protect optic nerve health.

How It Works

  • Latanoprost acts as a selective agonist of the prostaglandin F‑type (FP) receptor in the ciliary body, enhancing uveoscleral outflow of aqueous humor. This increased outflow reduces intra‑ocular pressure, thereby helping to preserve optic nerve function in glaucoma and ocular hypertension patients.

Side Effects

Common Side Effects

  • Eye redness: mild conjunctival hyperemia.
  • Increased eyelash growth: longer, thicker lashes.
  • Iris color change: gradual darkening of the iris.
  • Eye irritation: burning or stinging sensation.
  • Blurred vision: transient visual disturbance.
  • Foreign body sensation: feeling of grit in the eye.

Serious or Rare Side Effects

  • Severe allergic reaction: swelling, rash, or difficulty breathing.
  • Uveitis: inflammation of the uveal tract.
  • Macular edema: swelling of the central retina.
  • Vision loss: sudden decrease in visual acuity.
  • Ocular infection: signs of conjunctivitis or keratitis.

Precautions & Warnings

Before initiating therapy, clinicians should evaluate ocular health and monitor intra‑ocular pressure regularly.

  • Assess baseline intra‑ocular pressure: ensure appropriate therapeutic target.
  • Monitor iris color changes: inform patients of possible permanent darkening.
  • Avoid use in active ocular inflammation: may exacerbate condition.
  • Counsel on eyelash growth: discuss cosmetic implications.
  • Store at room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Latanoprost may interact with other ocular medications, affecting efficacy or safety.

Major Interactions (Avoid)

  • Concomitant prostaglandin analogs: risk of additive ocular effects.
  • Non‑steroidal anti‑inflammatory eye drops: may reduce latanoprost efficacy.

Moderate Interactions (Monitor Closely)

  • Beta‑blocker eye drops: possible additive intra‑ocular pressure lowering.
  • Systemic carbonic anhydrase inhibitors: enhanced pressure reduction.
  • Topical corticosteroids: may counteract latanoprost's effect.

Frequently Asked Questions

Monoprost is a prescription eye drop containing latanoprost, used to lower intra‑ocular pressure in patients with open‑angle glaucoma or ocular hypertension. By reducing pressure, it helps prevent optic nerve damage and preserve visual function.

Latanoprost is a prostaglandin F‑type (FP) receptor agonist. It increases the outflow of aqueous humor through the uveoscleral pathway, which lowers intra‑ocular pressure and reduces the risk of glaucoma‑related vision loss.

The dosing regimen for Monoprost is determined by the prescribing ophthalmologist. Typically, one drop is instilled into the affected eye(s) once daily in the evening, but the exact dose and schedule must follow the prescriber's instructions.

The safety of latanoprost in pregnancy or lactation has not been fully established. Healthcare providers should weigh potential benefits against risks and consider alternative treatments if the patient is pregnant or nursing.

To request Monoprost, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Monoprost belongs to the prostaglandin analog class, which generally offers once‑daily dosing and strong intra‑ocular pressure reduction. Compared with beta‑blocker or carbonic anhydrase inhibitor drops, prostaglandin analogs often have a more favorable dosing convenience but may cause cosmetic changes such as iris darkening.

Monoprost should be stored at room temperature, below 25 °C. Keep the bottle in its original packaging, protect it from direct light and moisture, and discard any solution that appears discolored or contains particles.

Monoprost is applied as a single drop into the conjunctival sac of the affected eye(s) once daily, preferably in the evening. The patient should avoid touching the tip of the bottle to the eye or any surface to maintain sterility.

Serious risks include severe allergic reactions, uveitis, macular edema, and sudden vision loss. Patients should seek immediate medical attention if they experience eye pain, redness, swelling, or any rapid change in vision.

Monoprost is contraindicated in patients with active ocular inflammation, known hypersensitivity to latanoprost or any component of the formulation, and should be used with caution in individuals with a history of intra‑ocular inflammation or retinal disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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