Product image of Monoprost (Latanoprost) supplied by GNH India

Monoprost

Active Ingredient:
Latanoprost
Origin:
EU

Monoprost (Latanoprost)

Latanoprost, the active ingredient in Monoprost, is a prostaglandin analog presented as eye drops for ocular use. It lowers intra‑ocular pressure and is indicated for open‑angle glaucoma and ocular hypertension in adults.

GNH India supplies Monoprost as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratoires Thea

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Indications & Clinical Uses

Monoprost is a prostaglandin analog used to manage conditions that involve elevated intra‑ocular pressure.

  • Open‑angle glaucoma: reduces eye pressure to slow optic nerve damage.
  • Ocular hypertension: lowers pressure to prevent progression to glaucoma.
  • Elevated intra‑ocular pressure (any cause): helps maintain normal pressure levels.

How It Works

  • Latanoprost binds to prostaglandin F (FP) receptors in the ciliary muscle, promoting remodeling of the extracellular matrix and increasing uveoscleral outflow of aqueous humor. This enhanced outflow lowers intra‑ocular pressure, providing therapeutic benefit in glaucoma and ocular hypertension.

Side Effects

Monoprost may cause a range of ocular reactions.

Common Side Effects

  • Eye redness: mild conjunctival hyperemia.
  • Increased eyelash growth: longer, thicker lashes.
  • Iris pigmentation change: gradual darkening of eye colour.
  • Eye irritation or foreign‑body sensation.
  • Blurred vision shortly after instillation.
  • Dry eye sensation.

Serious or Rare Side Effects

  • Severe eye inflammation (uveitis or iritis).
  • Allergic reaction: swelling, itching, or rash.
  • Sudden loss of vision.
  • Persistent eye pain.
  • Corneal edema.
  • Unusual changes in visual acuity.

Precautions & Warnings

Before using Monoprost, consider the following safety points.

  • Pregnancy: safety unknown; use only if benefits outweigh risks.
  • Breastfeeding: unknown excretion; caution advised.
  • Active ocular infection: contraindicated until resolved.
  • Monitor intra‑ocular pressure: assess response after initiation.
  • Contact lens wear: avoid using lenses for at least 15 minutes after instillation.
  • Store at room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Monoprost can interact with other ophthalmic agents and systemic medications.

Major Interactions (Avoid)

  • Concurrent use of other prostaglandin analog eye drops: additive pressure‑lowering effect may cause hypotony.
  • Non‑steroidal anti‑inflammatory eye drops: may diminish latanoprost efficacy.

Moderate Interactions (Monitor Closely)

  • Beta‑blocker eye drops: combined use may lead to excessive IOP reduction.
  • Carbonic anhydrase inhibitor eye drops: increased overall pressure‑lowering effect.
  • Systemic carbonic anhydrase inhibitors (e.g., acetazolamide): monitor for enhanced IOP decrease.

Frequently Asked Questions

Monoprost is an ophthalmic solution containing latanoprost, prescribed to lower intra‑ocular pressure in patients with open‑angle glaucoma or ocular hypertension. By reducing eye pressure, it helps prevent optic nerve damage and preserves visual function.

Latanoprost activates prostaglandin F (FP) receptors in the eye, which remodels the extracellular matrix of the ciliary body and increases uveoscleral outflow of aqueous humor. This enhanced drainage lowers intra‑ocular pressure, addressing the primary cause of glaucoma progression.

The prescribed dose of Monoprost is determined by the treating ophthalmologist. Typically, one drop is instilled into the affected eye(s) once daily in the evening, but exact dosing and timing should follow the prescriber’s instructions.

Safety data for latanoprost during pregnancy and lactation are limited. The product is classified as having an unknown pregnancy category, so it should be used only if the potential benefit justifies any potential risk to the fetus or infant.

To order Monoprost, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Monoprost belongs to the prostaglandin analog class, which generally offers once‑daily dosing and strong IOP‑lowering efficacy. Compared with beta‑blocker drops such as timolol, latanoprost often provides greater pressure reduction with a different side‑effect profile, notably affecting eyelash growth and iris colour.

Monoprost should be stored at room temperature, below 25 °C, in its original packaging. Protect the bottle from direct sunlight and moisture. Do not freeze the solution, and keep the dropper tip clean to avoid contamination.

Monoprost is applied as a single drop into the conjunctival sac of the affected eye(s) once daily, preferably in the evening. Tilt the head back, pull down the lower eyelid to form a pocket, and gently squeeze the bottle without touching the eye or lashes.

Serious adverse events, though rare, include severe eye inflammation such as uveitis or iritis, allergic reactions with swelling or rash, sudden loss of vision, and corneal edema. Patients should seek immediate medical attention if any of these symptoms occur.

Monoprost is contraindicated in individuals with active ocular infections, inflammation, or hypersensitivity to latanoprost or any component of the formulation. Caution is also advised for patients with a history of severe ocular inflammation or those who are pregnant or breastfeeding without clear benefit.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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