Product image of Monoprost (Latanoprost) supplied by GNH India

Monoprost

Active Ingredient:
Latanoprost
Origin:
EU

Monoprost (Latanoprost)

Latanoprost, the active ingredient in Monoprost, is a prostaglandin analog presented as an eye drops solution for ocular use. It lowers intra‑ocular pressure and is used in the management of open‑angle glaucoma and ocular hypertension in adults.

GNH India supplies Monoprost as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality and regulatory compliance across markets.

Manufacturer / TM Owner

Laboratoires Thea

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Indications & Clinical Uses

  • Monoprost, a prostaglandin analog, is employed in ocular conditions where reduction of intra‑ocular pressure is required.
  • Open‑angle glaucoma: reduces intra‑ocular pressure to slow disease progression.
  • Ocular hypertension: lowers eye pressure to prevent development of glaucoma.
  • Secondary glaucoma: helps control pressure when other therapies are insufficient.

How It Works

  • Latanoprost binds to prostaglandin F (FP) receptors in the ciliary muscle, activating the extracellular matrix remodeling pathway. This increases uveoscleral outflow of aqueous humor, thereby decreasing intra‑ocular pressure and providing therapeutic benefit in glaucoma and ocular hypertension.

Side Effects

Latanoprost may cause ocular and systemic reactions.

Common Side Effects

  • Eye redness: mild conjunctival hyperemia.
  • Increased eyelash growth: longer, thicker lashes.
  • Iris pigmentation change: gradual darkening of iris color.
  • Eye irritation: burning or stinging sensation.
  • Blurred vision: transient visual disturbance.
  • Foreign body sensation: feeling of grit in the eye.

Serious or Rare Side Effects

  • Severe allergic reaction: swelling, rash, or difficulty breathing.
  • Uveitis: inflammation of the uveal tract.
  • Macular edema: swelling of the central retina.
  • Paradoxical increase in intra‑ocular pressure.
  • Ocular infection: signs of bacterial or fungal involvement.

Precautions & Warnings

  • When prescribing or using Monoprost, consider the following safety measures.
  • Pregnancy: safety not established; use only if benefit outweighs risk.
  • Breastfeeding: unknown excretion; exercise caution.
  • Contact lens wearers: may cause deposits; remove lenses before instillation.
  • Active ocular inflammation: avoid until inflammation resolves.
  • Monitor intra‑ocular pressure regularly: adjust therapy based on readings.
  • Store at room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Latanoprost may interact with other ocular or systemic agents.

Major Interactions (Avoid)

  • Concurrent use of another prostaglandin analog: duplicate therapy may increase side‑effects.
  • Simultaneous administration of ocular corticosteroids: may reduce efficacy of pressure lowering.

Moderate Interactions (Monitor Closely):\n- Co‑administration with beta‑blocker eye drops: may cause excessive pressure reduction.

  • Use with carbonic anhydrase inhibitors: potential additive ocular irritation.
  • Systemic prostaglandin analogs: may enhance systemic prostaglandin effects.

Frequently Asked Questions

Monoprost contains latanoprost, a prostaglandin analog indicated for lowering intra‑ocular pressure in adults with open‑angle glaucoma or ocular hypertension, helping to prevent optic nerve damage and preserve visual function.

Latanoprost activates prostaglandin F (FP) receptors in the ciliary body, promoting remodeling of the extracellular matrix and increasing uveoscleral outflow of aqueous humor, which reduces intra‑ocular pressure.

The prescribed dose of Monoprost is determined by the treating ophthalmologist. Typically, one drop is instilled into the affected eye(s) once daily in the evening, but exact dosing must follow the prescriber’s instructions.

Safety data for latanoprost in pregnancy and lactation are limited. It should be used only if the potential benefit justifies the potential risk to the fetus or infant, and the prescriber should evaluate each case individually.

To order Monoprost, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Monoprost (latanoprost) is a prostaglandin analog, generally offering once‑daily dosing and strong intra‑ocular pressure reduction. Compared with beta‑blocker or carbonic anhydrase inhibitor drops, latanoprost often provides greater pressure‑lowering efficacy with a different side‑effect profile, such as increased eyelash growth and iris pigmentation.

Monoprost should be stored at room temperature, below 25 °C, in its original container. Keep the bottle tightly closed, protect it from light and moisture, and discard any solution that appears discolored or contains particles.

Monoprost is applied as a sterile eye‑drop solution. The patient should wash hands, tilt the head back, pull down the lower eyelid to form a pocket, and instill one drop into the prescribed eye(s) without touching the tip to the ocular surface. Close the eye gently for a few seconds after administration.

Serious risks, though rare, include severe allergic reactions, uveitis, macular edema, and paradoxical increase in intra‑ocular pressure. Patients should seek immediate medical attention if they experience sudden eye pain, vision loss, swelling, or systemic allergic symptoms.

Monoprost is contraindicated in patients with known hypersensitivity to latanoprost or any component of the formulation, and it should be used with caution in individuals with active ocular inflammation, recent ocular surgery, or those who are pregnant or breastfeeding without clear benefit.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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