Product image of Monoprost (Latanoprost) supplied by GNH India

Monoprost

Active Ingredient:
Latanoprost
Origin:
EU

Monoprost (Latanoprost)

Latanoprost, the active ingredient in Monoprost, is a prostaglandin analog presented as sterile eye drops for ocular administration. It reduces intra‑ocular pressure by enhancing aqueous humor outflow and is indicated for the treatment of open‑angle glaucoma and ocular hypertension in adult patients.

GNH India supplies Monoprost as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches to meet global demand. Monoprost complies with European Union pharmaceutical regulations and is distributed across multiple international markets.

Manufacturer / TM Owner

Laboratoires Thea

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Indications & Clinical Uses

  • Monoprost (latanoprost) is a prostaglandin analog used in ocular hypotensive therapy to lower intra‑ocular pressure.
  • Open-angle glaucoma: reduces intra‑ocular pressure to slow visual field loss.
  • Ocular hypertension: lowers pressure to prevent progression to glaucoma.
  • Pseudoexfoliative glaucoma: helps control pressure in this secondary open‑angle condition.

How It Works

  • Latanoprost binds to the FP (prostanoid) receptors on the ciliary muscle, activating a cascade that remodels extracellular matrix and increases uveoscleral outflow of aqueous humor. The enhanced outflow lowers intra‑ocular pressure, providing therapeutic benefit in glaucomatous conditions.

Side Effects

Common Side Effects

  • Eye redness (hyperemia)
  • Increased eyelash length and thickness
  • Darkening of the iris pigment
  • Eye irritation or foreign‑body sensation
  • Blurred vision
  • Mild ocular discomfort

Serious or Rare Side Effects

  • Uveitis or severe ocular inflammation
  • Macular edema leading to vision changes
  • Allergic reaction with swelling or rash
  • Paradoxical increase in intra‑ocular pressure
  • Endophthalmitis or severe eye infection

Precautions & Warnings

Before initiating therapy, evaluate baseline intra‑ocular pressure and ocular health.

  • Assess for active eye infection: postpone use until resolved.
  • Monitor iris color and eyelash changes: document any progression.
  • Caution in patients with a history of uveitis or corneal transplantation.
  • Pregnancy and lactation: safety not established; use only if benefit outweighs risk.
  • Store at room temperature: keep bottle tightly closed, protect from light and moisture.

Avoid Interactions

Latanoprost may interact with other ocular agents.

Major Interactions (Avoid)

  • Concurrent use with other prostaglandin analogs: risk of additive ocular effects.
  • Combination with ocular corticosteroids: may diminish prostaglandin efficacy.

Moderate Interactions (Monitor Closely):\n- Co‑administration with beta‑blocker eye drops: monitor intra‑ocular pressure for excessive reduction.

  • Use with alpha‑agonist eye drops: observe pressure changes.
  • Systemic antihistamines: may increase ocular dryness, advise patient monitoring.

Frequently Asked Questions

Monoprost contains latanoprost, a prostaglandin analog indicated for lowering intra‑ocular pressure in adults with open‑angle glaucoma or ocular hypertension. By reducing pressure, it helps prevent optic nerve damage and visual field loss associated with these conditions.

Latanoprost binds to FP receptors in the eye, triggering biochemical changes that remodel the extracellular matrix of the ciliary body. This increases uveoscleral outflow of aqueous humor, thereby lowering intra‑ocular pressure and providing therapeutic benefit in glaucoma and ocular hypertension.

The dosing regimen for Monoprost is determined by the prescribing ophthalmologist. Typically, one drop is instilled into the affected eye(s) once daily in the evening, but the exact dose and timing should follow the prescriber’s instructions.

Safety of latanoprost in pregnancy and lactation has not been established. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision must be made by the treating physician.

To order Monoprost, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Monoprost (latanoprost) is a prostaglandin analog, a class known for once‑daily dosing and strong intra‑ocular pressure reduction. Compared with beta‑blocker or carbonic anhydrase inhibitor drops, prostaglandin analogs often achieve greater pressure lowering with a favorable dosing schedule, though individual response varies.

Monoprost should be stored at room temperature, below 25 °C, in its original container. Keep the bottle tightly closed, protect it from light and moisture, and discard any solution that appears discolored or contaminated.

Monoprost is administered as a sterile eye drop. The patient should wash their hands, tilt the head back, pull down the lower eyelid to create a pocket, and place one drop into the conjunctival sac of the prescribed eye(s). Avoid touching the tip of the bottle to any surface.

Serious risks, though rare, include severe ocular inflammation such as uveitis, macular edema that can affect vision, and paradoxical increases in intra‑ocular pressure. Patients should report any sudden vision changes, eye pain, or redness to their eye care professional promptly.

Monoprost is contraindicated in patients with known hypersensitivity to latanoprost or any component of the formulation. It should also be avoided in eyes with active intra‑ocular inflammation, infection, or in patients who have had recent ocular surgery unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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