Product image of Monoprost (Latanoprost) supplied by GNH India

Monoprost

Active Ingredient:
Latanoprost
Origin:
EU

Monoprost (Latanoprost)

Latanoprost, the active ingredient in Monoprost, is a prostaglandin analog presented as an ophthalmic solution for ocular use. It is employed to lower intra‑ocular pressure in patients with open‑angle glaucoma or ocular hypertension.
GNH India supplies Monoprost as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratoires Thea

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Indications & Clinical Uses

  • Monoprost, a prostaglandin analog, is used to manage conditions that involve elevated intra‑ocular pressure.
  • Open‑angle glaucoma: reduces intra‑ocular pressure to slow disease progression.
  • Ocular hypertension: lowers eye pressure to prevent development of glaucoma.

How It Works

  • Latanoprost binds to prostaglandin F (FP) receptors in the ciliary body, enhancing uveoscleral outflow of aqueous humor. By increasing this unconventional drainage pathway, the drug effectively reduces intra‑ocular pressure, helping to protect the optic nerve from pressure‑related damage.

Side Effects

Latanoprost may cause ocular and systemic reactions. Patients should be aware of both frequent and less common events.

Common Side Effects

  • Eye redness or hyperemia
  • Increased eyelash length and thickness
  • Darkening of the iris color
  • Eye irritation or foreign‑body sensation
  • Blurred vision
  • Mild eye pain or discomfort

Serious or Rare Side Effects

  • Severe allergic reaction (e.g., swelling, rash)
  • Uveitis or intra‑ocular inflammation
  • Macular edema leading to vision changes
  • Sudden loss of vision
  • Ocular infection
  • Persistent eye pain requiring medical attention

Precautions & Warnings

Before initiating therapy, clinicians should consider several safety aspects.

  • Monitor intra‑ocular pressure: schedule regular measurements to assess efficacy.
  • Assess for ocular infection: avoid use if active infection is present.
  • Avoid use in active ocular inflammation: may exacerbate the condition.
  • Use with caution in patients with a history of herpetic eye disease.
  • Store at room temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Latanoprost can interact with other ophthalmic or systemic agents, influencing efficacy or safety.

Major Interactions (Avoid)

  • Concomitant use of other prostaglandin analog eye drops: increased risk of additive side effects.
  • Use with non‑steroidal anti‑inflammatory eye drops: may diminish IOP‑lowering effect.

Moderate Interactions (Monitor Closely):\n- Beta‑blocker eye drops: additive intra‑ocular pressure reduction.

  • Topical corticosteroids: potential reduction in therapeutic response.
  • Systemic antihistamines: may affect ocular surface tolerance.

Frequently Asked Questions

Monoprost contains latanoprost, a prostaglandin analog prescribed to lower intra‑ocular pressure in adults with open‑angle glaucoma or ocular hypertension, helping to prevent optic nerve damage and preserve vision.

Latanoprost activates prostaglandin F (FP) receptors in the eye, increasing the uveoscleral outflow of aqueous humor. This enhanced drainage reduces intra‑ocular pressure, which is the primary therapeutic goal in glaucoma and ocular hypertension.

The dosing regimen for Monoprost is determined by the prescribing ophthalmologist. Typically, a single drop is instilled in the affected eye(s) once daily in the evening, but the exact schedule should follow the clinician’s instructions.

Safety data for latanoprost in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by the treating physician.

To request Monoprost, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Monoprost (latanoprost) is a prostaglandin analog, generally offering once‑daily dosing and a favorable efficacy profile compared with beta‑blocker or carbonic anhydrase inhibitor drops. Its side‑effect profile, such as iris darkening, differs from other classes, making individual patient factors important in selection.

Monoprost should be stored at room temperature, below 25 °C, in the original packaging. Protect the bottle from direct sunlight and moisture to maintain stability. Do not freeze the product.

Monoprost is applied as a single drop into the conjunctival sac of the affected eye(s) once daily, preferably in the evening. Patients should wash their hands before use, avoid touching the tip to the eye or any surface, and close the eye gently after instillation.

Serious risks, though rare, include severe allergic reactions, uveitis, macular edema, and sudden loss of vision. Any sudden eye pain, redness, or visual changes should prompt immediate medical evaluation.

Monoprost is contraindicated in patients with known hypersensitivity to latanoprost or any component of the formulation, and it should be avoided in eyes with active inflammation or infection. Clinicians should also exercise caution in patients with a history of herpetic eye disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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