Product image of Monoprost (Latanoprost) supplied by GNH India

Monoprost

Active Ingredient:
Latanoprost
Origin:
EU

Monoprost (Latanoprost)

Latanoprost, the active ingredient in Monoprost, is a prostaglandin analog presented as an eye drops solution for ocular use. It lowers intra‑ocular pressure and is used in the management of glaucoma and ocular hypertension in adults.

GNH India supplies Monoprost as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratoires Thea

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Indications & Clinical Uses

Monoprost is a prostaglandin analog indicated for conditions that require reduction of intra‑ocular pressure.

  • Open‑angle glaucoma: lowers intra‑ocular pressure to prevent optic nerve damage.
  • Ocular hypertension: reduces elevated eye pressure to lower the risk of developing glaucoma.
  • Secondary open‑angle glaucoma (e.g., pseudoexfoliative): provides pressure‑lowering effect similar to primary forms.

How It Works

  • Latanoprost is a prostaglandin F2α analogue that binds to FP receptors in the ciliary body, enhancing uveoscleral outflow of aqueous humor. This increased outflow reduces intra‑ocular pressure, helping to protect the optic nerve from pressure‑related damage.

Side Effects

Latanoprost may cause ocular and systemic reactions.

Common Side Effects

  • Eye redness: mild conjunctival hyperemia.
  • Increased eyelash growth: longer, thicker lashes.
  • Iris darkening: gradual pigmentation change.
  • Eye irritation or foreign‑body sensation.
  • Blurred vision: transient after instillation.
  • Periorbital skin darkening.

Serious or Rare Side Effects

  • Severe eye inflammation (uveitis, iritis).
  • Allergic reactions: swelling, itching, rash.
  • Paradoxical increase in intra‑ocular pressure.
  • Vision loss: sudden or progressive.
  • Corneal edema or keratitis.
  • Macular edema, especially in diabetic patients.

Precautions & Warnings

Before using Monoprost, consider the following safety measures.

  • Pregnancy: safety not established; use only if clearly needed.
  • Breastfeeding: unknown safety; weigh benefits against potential risks.
  • Contact lens wear: avoid during treatment as lenses may absorb the drug.
  • Intra‑ocular pressure monitoring: schedule regular assessments to gauge efficacy.
  • Concomitant prostaglandin analogs: avoid simultaneous use to prevent additive effects.
  • Store at room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Latanoprost can interact with other ocular or systemic agents.

Major Interactions (Avoid)

  • Non‑steroidal anti‑inflammatory eye drops: may diminish pressure‑lowering effect.
  • Systemic prostaglandin synthesis inhibitors (e.g., indomethacin): could antagonize action.

Moderate Interactions (Monitor Closely)

  • Beta‑blocker eye drops: additive intra‑ocular pressure reduction, monitor for hypotony.
  • Carbonic anhydrase inhibitor eye drops: increased risk of ocular irritation.
  • Systemic carbonic anhydrase inhibitors (e.g., acetazolamide): may enhance ocular side effects.
  • Topical corticosteroids: potential for increased intra‑ocular pressure, require close observation.

Frequently Asked Questions

Monoprost contains latanoprost, a prostaglandin analogue prescribed to lower intra‑ocular pressure in patients with open‑angle glaucoma or ocular hypertension, helping to prevent optic nerve damage and preserve vision.

Latanoprost binds to FP receptors in the eye’s ciliary body, increasing uveoscleral outflow of aqueous humor. This enhanced drainage reduces intra‑ocular pressure, which is the primary therapeutic goal in glaucoma management.

The dosing regimen for Monoprost is determined by the prescribing clinician. Typically, one drop is instilled into the affected eye(s) once daily in the evening, but exact instructions must follow the prescriber’s order.

Safety data for latanoprost in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.

To request Monoprost, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and necessary import documentation.

Monoprost (latanoprost) is a prostaglandin analogue, generally offering once‑daily dosing and strong intra‑ocular pressure reduction. Compared with beta‑blocker drops, it often provides greater efficacy with a different side‑effect profile, such as increased eyelash growth and iris pigmentation.

Monoprost eye drops should be stored at room temperature, away from direct sunlight. Keep the bottle tightly closed, in its original packaging, and protect it from moisture. Do not freeze the solution.

Monoprost is applied as a single drop into the conjunctival sac of the affected eye(s) once daily, preferably in the evening. The patient should avoid touching the tip of the bottle to the eye or any surface to maintain sterility.

Serious risks include severe eye inflammation (uveitis or iritis), paradoxical increase in intra‑ocular pressure, and rare cases of vision loss. Patients should report any sudden pain, redness, or visual changes to their eye care professional immediately.

Monoprost is contraindicated in patients with known hypersensitivity to latanoprost or any component of the formulation, and should be used with caution in individuals with active ocular infections, severe inflammation, or those who are pregnant without clear medical justification.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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