Product image of Monoprost (Latanoprost) supplied by GNH India

Monoprost

Active Ingredient:
Latanoprost
Origin:
EU

Monoprost (Latanoprost)

Latanoprost, the active ingredient in Monoprost, is a prostaglandin analog presented as an ophthalmic solution for ocular use. It is employed to lower intra‑ocular pressure in patients with open‑angle glaucoma or ocular hypertension, helping to preserve visual function.

GNH India supplies Monoprost as a licensed, GDP‑compliant international pharmaceutical product to hospitals, pharmacies and clinics worldwide, adhering to stringent quality standards and regulatory requirements for ophthalmic medicines. The company’s global distribution network ensures reliable delivery and support for eye‑care providers across diverse markets.

Manufacturer / TM Owner

Laboratoires Thea

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Indications & Clinical Uses

  • Latanoprost is a prostaglandin analog used to manage conditions characterized by elevated intra‑ocular pressure.
  • Open‑angle glaucoma: reduces intra‑ocular pressure to slow disease progression.
  • Ocular hypertension: lowers pressure to prevent conversion to glaucoma.
  • Secondary open‑angle glaucoma: assists in pressure control when other ocular conditions contribute to elevated pressure.

How It Works

  • Latanoprost binds to prostaglandin F (FP) receptors in the ciliary muscle, activating the extracellular matrix remodeling pathway. This increases uveoscleral outflow of aqueous humor, thereby decreasing intra‑ocular pressure and helping to protect the optic nerve from pressure‑related damage.

Side Effects

Latanoprost may cause ocular and systemic reactions.

Common Side Effects

  • Eye redness or hyperemia.
  • Increased eyelash length and thickness.
  • Darkening of the iris pigment.
  • Eye irritation or foreign‑body sensation.
  • Blurred vision.
  • Mild eye pain.

Serious or Rare Side Effects

  • Severe allergic reaction (e.g., angio‑edema, anaphylaxis).
  • Uveitis or intra‑ocular inflammation.
  • Corneal edema or keratitis.
  • Paradoxical increase in intra‑ocular pressure.
  • Persistent visual disturbances.
  • Endophthalmitis (rare infection inside the eye).

Precautions & Warnings

  • Before using Monoprost, consider the following precautions.
  • Monitor IOP: schedule regular intra‑ocular pressure measurements.
  • Assess for ocular infections: avoid use if active eye infection is present.
  • Avoid in active uveitis: contraindicated in inflammatory eye conditions.
  • Check for hypersensitivity: discontinue if allergic signs appear.
  • Pregnancy and lactation: safety not established; use only if benefit outweighs risk.
  • Store at room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Latanoprost may interact with other ocular or systemic agents.

Major Interactions (Avoid)

  • Co‑administration with other prostaglandin analog eye drops: increased risk of ocular side effects.
  • Use with preservative‑containing contact lens solutions: may heighten ocular irritation.

Moderate Interactions (Monitor Closely)

  • Systemic carbonic anhydrase inhibitors: possible additive IOP‑lowering effect.
  • Topical corticosteroids: may reduce latanoprost efficacy.
  • Anticholinergic eye drops: may affect pupil dynamics and IOP control.

Frequently Asked Questions

Monoprost contains latanoprost, a prostaglandin analog prescribed to lower intra‑ocular pressure in patients with open‑angle glaucoma or ocular hypertension, helping to prevent optic nerve damage and preserve vision.

Latanoprost activates prostaglandin F (FP) receptors in the eye, enhancing uveoscleral outflow of aqueous humor. This increased drainage reduces intra‑ocular pressure, which is the primary therapeutic goal in glaucoma management.

The dosing regimen for Monoprost is determined by the prescribing ophthalmologist. Typically, one drop is instilled in the affected eye(s) once daily in the evening, but the exact dose and timing must follow the prescriber’s instructions.

Safety data for latanoprost in pregnancy and lactation are limited. It should be used only if the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by the treating physician.

To request Monoprost, submit an enquiry on the product page at gnhindia.com indicating the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Monoprost belongs to the prostaglandin analog class, which generally offers once‑daily dosing and strong IOP‑lowering efficacy. Compared with beta‑blocker or carbonic anhydrase inhibitor drops, prostaglandin analogs often have a more favorable dosing schedule but may cause distinct ocular side effects such as iris pigmentation.

Monoprost should be stored at room temperature, below 25 °C, in its original container. Protect the bottle from light and moisture, and keep it out of reach of children.

Monoprost is applied as an ophthalmic solution. The patient should wash hands, tilt the head back, pull down the lower eyelid, and place a single drop into the conjunctival sac of the prescribed eye(s) without touching the tip of the bottle to the eye.

Serious risks include severe allergic reactions, uveitis, corneal edema, and a paradoxical rise in intra‑ocular pressure. Patients should seek immediate medical attention if they experience significant eye pain, vision changes, or signs of an allergic response.

Monoprost is contraindicated in patients with active ocular inflammation such as uveitis, known hypersensitivity to latanoprost or any component of the formulation, and should be used with caution in pregnant or nursing women unless clearly indicated by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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