Product image of Montalis (Montelukast Sodium) supplied by GNH India

Montalis

Active Ingredient:
Montelukast Sodium
Origin:
EU

Montalis (Montelukast Sodium)

Montelukast, the active ingredient in Montalis, is a leukotriene receptor antagonist presented as an oral dosage form for oral use. It treats asthma and allergic rhinitis by reducing inflammation and bronchoconstriction in patients of all ages.

GNH India supplies Montalis as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Zwitter Pharmaceuticals Επε

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Indications & Clinical Uses

Montalis, a leukotriene receptor antagonist, is used to manage conditions driven by leukotriene‑mediated inflammation.

  • Asthma: improves control of chronic asthma and reduces frequency of exacerbations.
  • Allergic rhinitis: alleviates nasal congestion, sneezing and itching associated with seasonal allergies.
  • Exercise‑induced bronchoconstriction: prevents airway narrowing triggered by physical activity.

How It Works

  • Montelukast selectively blocks the cysteinyl leukotriene receptor CysLT1 on airway smooth muscle and inflammatory cells. By antagonizing this receptor, it inhibits leukotriene‑induced bronchoconstriction, mucus secretion, and vascular permeability, thereby reducing airway inflammation and hyper‑responsiveness.

Side Effects

Montalis may cause a range of adverse reactions, which are categorized by frequency.

Common Side Effects

  • Headache: mild to moderate pain often reported during treatment.
  • Abdominal pain: discomfort or cramps in the stomach area.
  • Cough: occasional irritation of the throat leading to coughing.
  • Sore throat: mild irritation or pain in the throat.

Serious or Rare Side Effects

  • Mood changes: including depression, anxiety, or suicidal thoughts.
  • Stevens‑Johnson syndrome: severe skin reaction with blistering.
  • Angioedema: rapid swelling of the face, lips, or tongue that may affect breathing.

Precautions & Warnings

Before prescribing Montalis, clinicians should consider several safety measures.

  • Assess asthma control: ensure patient is on appropriate inhaled therapy before adding montelukast.
  • Monitor neuropsychiatric symptoms: watch for mood changes, depression, or suicidal ideation.
  • Use caution in hepatic impairment: dose adjustment may be required in patients with liver dysfunction.
  • Avoid in patients with known hypersensitivity to montelukast or any excipients.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Montelukast can interact with other medicines, requiring attention to avoid reduced efficacy or increased toxicity.

Major Interactions (Avoid)

  • Ritonavir: may increase montelukast plasma concentrations.
  • Phenobarbital: may lower montelukast levels, reducing effectiveness.
  • Carbamazepine: can decrease montelukast exposure.

Moderate Interactions (Monitor Closely)

  • Warfarin: potential alteration of INR, requiring closer monitoring.
  • Theophylline: additive bronchospasm risk; observe respiratory status.

Frequently Asked Questions

Montalis, containing montelukast, is prescribed to manage chronic asthma, relieve symptoms of allergic rhinitis, and prevent exercise‑induced bronchoconstriction. It works by reducing airway inflammation and narrowing caused by leukotrienes.

Montelukast blocks the cysteinyl leukotriene receptor CysLT1 on airway smooth muscle and inflammatory cells. This inhibition prevents leukotriene‑mediated bronchoconstriction, mucus production, and vascular leakage, helping to keep the airways open and less inflamed.

The appropriate dose of Montalis is determined by the prescribing healthcare professional based on the patient’s age, weight, and specific condition. Dosage instructions are individualized and should be followed exactly as written on the prescription label.

Safety data for montelukast in pregnancy and lactation are limited. Healthcare providers should weigh potential benefits against risks before prescribing Montalis to pregnant or nursing individuals, and discuss any concerns with the patient.

To request Montalis, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Montalis belongs to the leukotriene receptor antagonist class, offering an oral alternative to inhaled corticosteroids or long‑acting beta‑agonists. It is especially useful for patients who need additional control of leukotriene‑driven inflammation or who prefer a non‑inhaled option.

Montalis should be stored at room temperature, below 25 °C, in its original packaging. Keep the product away from moisture and direct sunlight to maintain stability and potency throughout its shelf life.

Montalis is taken orally, usually once daily, with or without food, as directed by the prescriber. The tablet should be swallowed whole with water and not chewed or crushed unless specifically instructed.

Serious risks include neuropsychiatric events such as depression, suicidal thoughts, and rare severe skin reactions like Stevens‑Johnson syndrome or angioedema. Patients should be advised to seek immediate medical attention if they experience mood changes, rash, or swelling of the face or throat.

Montalis is contraindicated in individuals with known hypersensitivity to montelukast or any of its excipients. Caution is also advised for patients with severe hepatic impairment or those taking interacting medications that may alter its effectiveness.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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