Product image of Montelucaste Bluefish (Montelukast) supplied by GNH India

Montelucaste Bluefish

Active Ingredient:
Montelukast
Origin:
EU

Montelucaste Bluefish (Montelukast)

Montelukast, the active ingredient in Montelucaste Bluefish, is a leukotriene receptor antagonist presented as an oral dosage form for oral use. It is indicated for the management of asthma, exercise‑induced bronchoconstriction, allergic rhinitis and chronic urticaria in adults and children as prescribed by a healthcare professional.

GNH India supplies Montelucaste Bluefish as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bluefish Pharmaceuticals Ab

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Indications & Clinical Uses

Montelukast acts on leukotriene pathways to control inflammatory airway conditions.

  • Asthma: reduces the frequency of wheezing episodes and improves lung function in persistent asthma.
  • Exercise‑induced bronchoconstriction: prevents airway narrowing triggered by physical activity.
  • Allergic rhinitis: alleviates nasal congestion, sneezing and itching caused by seasonal allergens.
  • Chronic urticaria: decreases the occurrence of hives and associated itching in patients with refractory chronic urticaria.

How It Works

  • Montelukast selectively blocks the cysteinyl leukotriene receptor CysLT1 on airway smooth muscle and inflammatory cells. By antagonizing this receptor, it inhibits the actions of leukotrienes that cause bronchoconstriction, mucus secretion, vascular permeability, and eosinophil recruitment, thereby reducing airway inflammation and hyper‑responsiveness.

Side Effects

Montelukast is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Upper respiratory tract infection: transient symptoms.
  • Dyspepsia: occasional stomach discomfort.
  • Cough: non‑productive.
  • Fatigue: feeling of tiredness.
  • Nasopharyngitis: mild nasal inflammation.

Serious or Rare Side Effects

  • Neuropsychiatric events: agitation, anxiety, or mood changes.
  • Allergic reactions: rash, angioedema, or urticaria.
  • Hepatotoxicity: abnormal liver enzymes.
  • Stevens‑Johnson syndrome: severe skin blistering.
  • Anaphylaxis: rapid onset of systemic allergic response.

Precautions & Warnings

Montelukast should be used with consideration of the following precautions.

  • Pregnancy: safety not established; discuss risks with a healthcare provider.
  • Breastfeeding: assess benefit‑risk ratio before use.
  • Hepatic impairment: monitor liver function in patients with liver disease.
  • Concomitant asthma therapy: do not discontinue inhaled corticosteroids without medical advice.
  • Age restrictions: use in children only as directed by a prescriber.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, and protect from moisture.

Avoid Interactions

Montelukast may interact with several medicines; monitoring is advised.

Major Interactions (Avoid)

  • Phenobarbital: may reduce montelukast plasma concentrations.
  • Rifampin: induces metabolism, potentially decreasing efficacy.

Moderate Interactions (Monitor Closely)

  • Antidepressants (e.g., fluoxetine): may increase risk of neuropsychiatric effects.
  • Antihistamines: additive sedation is uncommon but possible.
  • CYP3A4 inhibitors (e.g., ketoconazole): may modestly raise montelukast levels.
  • Warfarin: monitor INR as theoretical interaction exists.
  • Oral contraceptives: no significant interaction, but standard monitoring applies.

Frequently Asked Questions

Montelucaste Bluefish contains the active ingredient montelukast, which is prescribed to manage chronic asthma, prevent exercise‑induced bronchoconstriction, relieve symptoms of allergic rhinitis, and treat chronic urticaria that does not respond to standard antihistamines.

Montelukast blocks the cysteinyl leukotriene receptor CysLT1 on airway smooth muscle and inflammatory cells. This inhibition prevents leukotriene‑mediated bronchoconstriction, mucus production, and inflammation, helping to keep the airways open and reduce allergic symptoms.

The appropriate dose of Montelucaste Bluefish is determined by the prescribing clinician based on the patient’s age, weight, condition being treated, and response to therapy. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for montelukast in pregnancy are limited, and the drug is classified as pregnancy category unknown. It should only be used if the potential benefit justifies any potential risk to the fetus. While limited data exist for lactation, a healthcare professional should evaluate the risk‑benefit ratio before use while breastfeeding.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Montelukast belongs to the leukotriene receptor antagonist class, offering an oral alternative to inhaled corticosteroids and long‑acting beta‑agonists. It is particularly useful for patients with aspirin‑exacerbated respiratory disease or those who need additional control of nighttime symptoms, but it does not replace rescue bronchodilators for acute attacks.

Store Montelucaste Bluefish at ambient temperature, preferably below 25 °C. Keep the tablets in the original blister pack or container, protect them from moisture and direct sunlight, and keep out of reach of children.

Montelucaste Bluefish is taken orally, usually once daily in the evening, with or without food, as directed by a healthcare professional. The tablet should be swallowed whole with a glass of water; it should not be crushed, chewed, or split unless specifically advised.

Serious adverse events, although rare, include neuropsychiatric reactions such as agitation, anxiety, depression, or suicidal thoughts, as well as severe allergic responses like anaphylaxis and Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they experience mood changes, rash, swelling, or breathing difficulties.

Montelucaste Bluefish is contraindicated in individuals with known hypersensitivity to montelukast or any of the tablet’s excipients. Caution is advised for patients with severe liver impairment, and it should be avoided in pregnant or breastfeeding women unless the prescriber determines that the benefits outweigh the risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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