Product image of Montelucaste Farmoz (Montelukast) supplied by GNH India

Montelucaste Farmoz

Active Ingredient:
Montelukast
Origin:
EU

Montelucaste Farmoz (Montelukast)

Montelukast, the active ingredient in Montelucaste Farmoz, is a leukotriene receptor antagonist presented as an oral tablet for oral use. It treats asthma, allergic rhinitis and exercise‑induced bronchoconstriction in adults and children.

GNH India supplies Montelucaste Farmoz as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The product is manufactured in the European Union under EU GMP standards and is available for export to regulated markets. Our supply chain ensures consistent quality and on‑time delivery to meet clinical demand.

Manufacturer / TM Owner

Farmoz - Sociedade Técnico Medicinal, S.A.

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Indications & Clinical Uses

Montelukast is used to manage conditions involving leukotriene‑mediated airway inflammation.

  • Asthma: reduces frequency of bronchospasm, improves daytime symptom control and decreases reliance on rescue inhalers.
  • Allergic rhinitis: alleviates nasal congestion, sneezing, itchy eyes and post‑nasal drip.
  • Exercise‑induced bronchoconstriction: prevents airway narrowing triggered by physical activity, allowing better exercise tolerance.

How It Works

  • Montelukast selectively blocks the cysteinyl leukotriene receptor CysLT1 on airway smooth‑muscle cells, mast cells and eosinophils. By preventing leukotriene D4 binding, it inhibits leukotriene‑induced bronchoconstriction, vascular permeability and inflammatory cell recruitment, thereby reducing airway edema and hyper‑responsiveness associated with asthma and allergic rhinitis. This antagonism also dampens late‑phase allergic responses, contributing to overall improvement in respiratory function.

Side Effects

Montelukast may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Abdominal pain: occasional discomfort.
  • Cough: transient.
  • Diarrhea: loose stools.
  • Nasopharyngitis: mild upper respiratory infection symptoms.
  • Rash: mild skin irritation.

Serious or Rare Side Effects

  • Mood changes: depression, anxiety or suicidal thoughts.
  • Allergic reactions: angioedema, urticaria or anaphylaxis.
  • Hepatotoxicity: elevated liver enzymes or hepatitis.
  • Stevens‑Johnson syndrome: severe skin blistering.
  • Blood disorders: eosinophilia or neutropenia.

Precautions & Warnings

Before prescribing Montelucaste Farmoz, clinicians should consider several precautionary measures to ensure safe use.

  • Pregnancy: safety data are limited; use only if potential benefit justifies risk.
  • Breastfeeding: monitor infant for possible effects; decision based on risk‑benefit assessment.
  • Hepatic impairment: dose adjustment may be required; monitor liver function.
  • Concomitant asthma therapy: continue inhaled corticosteroids; do not replace controller meds.
  • Neuropsychiatric symptoms: observe for mood changes, depression or suicidal ideation.
  • Store at ambient temperature below 25°C: keep in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Montelukast can interact with other medicines, affecting its efficacy or safety.

Major Interactions (Avoid)

  • Phenobarbital: may reduce montelukast plasma concentrations.
  • Rifampin: induces metabolism leading to decreased effectiveness.
  • St. John’s wort: strong enzyme inducer that can lower drug levels.

Moderate Interactions (Monitor Closely)

  • Antidepressants (SSRIs, SNRIs): may increase risk of neuropsychiatric events.
  • Antifungal azoles (ketoconazole, itraconazole): can raise montelukast exposure.
  • Warfarin: monitor INR as occasional interaction reported.

Frequently Asked Questions

Montelucaste Farmoz contains the active ingredient montelukast, a leukotriene receptor antagonist indicated for the management of asthma, allergic rhinitis and exercise‑induced bronchoconstriction. It helps control airway inflammation and reduces the frequency of bronchospasm in patients with these respiratory conditions.

Montelukast works by selectively blocking the cysteinyl leukotriene receptor CysLT1 on airway smooth‑muscle cells, mast cells and eosinophils. This inhibition prevents leukotriene‑mediated bronchoconstriction, vascular leakage and inflammatory cell recruitment, thereby reducing airway swelling and hyper‑responsiveness.

The dosage of Montelucaste Farmoz is determined by the prescribing healthcare professional based on the patient’s age, weight, severity of disease and response to therapy. The prescriber will select the appropriate strength and dosing schedule in accordance with approved labeling.

Safety data for montelukast in pregnancy are limited, and the product should be used only if the potential benefit outweighs any possible risk to the fetus. During breastfeeding, the drug passes into milk in small amounts; clinicians should weigh the benefits to the mother against potential effects on the infant.

To place an order, submit an enquiry on the Montelucaste Farmoz product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the sales team provides pricing, availability, shipping details and any necessary import documentation.

Montelucaste Farmoz belongs to the leukotriene receptor antagonist class, offering an oral alternative to inhaled corticosteroids or long‑acting beta‑agonists. While it is effective for mild‑to‑moderate asthma and allergic rhinitis, it is generally used as an add‑on therapy rather than a sole controller in severe cases. Compared with other leukotriene antagonists such as zafirlukast, montelukast has a once‑daily dosing convenience and a broader safety profile.

Montelucaste Farmoz tablets should be stored at ambient temperature below 25 °C, protected from moisture, heat and direct sunlight. Keep the product in its original blister pack until use and avoid storing in bathrooms or other humid environments to maintain potency.

The medication is supplied as oral tablets that are swallowed whole with a glass of water. It is usually taken once daily in the evening, but the exact timing and any food considerations should follow the prescribing clinician’s instructions.

Serious adverse events include neuropsychiatric reactions such as depression, anxiety, suicidal thoughts, as well as severe allergic responses like angioedema, urticaria or anaphylaxis. Hepatotoxicity and rare skin disorders such as Stevens‑Johnson syndrome have also been reported. Patients should be monitored closely for any of these symptoms.

Montelucaste Farmoz is contraindicated in individuals with known hypersensitivity to montelukast or any of the tablet excipients. Caution is advised for patients with a history of neuropsychiatric disorders, severe hepatic impairment, or those who are pregnant or breastfeeding without a clear clinical indication.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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