Product image of Montelucaste Tecnigen (Montelukast) supplied by GNH India

Montelucaste Tecnigen

Active Ingredient:
Montelukast
Origin:
EU

Montelucaste Tecnigen (Montelukast)

Montelukast, the active ingredient in Montelucaste Tecnigen, is a leukotriene receptor antagonist presented as an oral tablet for oral use. It treats asthma and allergic rhinitis in adults and children, helping to control symptoms and reduce flare‑ups.
GNH India supplies Montelucaste Tecnigen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Pentafarma - Sociedade Tecnico-Medicinal S.A.

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Indications & Clinical Uses

Montelukast acts on leukotriene pathways that contribute to airway inflammation and nasal symptoms.

  • Asthma: improves long‑term control and reduces the frequency of exacerbations.
  • Allergic rhinitis: relieves nasal congestion, sneezing, itching and runny nose.
  • Exercise‑induced bronchoconstriction: prevents bronchospasm triggered by physical activity.

How It Works

  • Montelukast selectively blocks the cysteinyl leukotriene receptor CysLT1, preventing leukotrienes D4, E4 and related cysteinyl leukotrienes from binding. This inhibition reduces bronchoconstriction, vascular permeability, mucus secretion, and inflammatory cell recruitment in the airways, thereby improving respiratory function and alleviating allergic nasal inflammation.

Side Effects

Montelukast is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Headache: mild to moderate pain often resolving without treatment.
  • Abdominal pain: discomfort or cramping in the stomach area.
  • Nausea: feeling of queasiness that may lead to vomiting.
  • Dizziness: transient light‑headedness or unsteadiness.

Serious or Rare Side Effects

  • Allergic reactions: including rash, angioedema or anaphylaxis.
  • Neuropsychiatric events: mood changes, depression or suicidal thoughts.
  • Hepatic enzyme elevation: abnormal liver function tests.
  • Severe skin reactions: such as Stevens‑Johnson syndrome or toxic epidermal necrolysis.

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Monitor neuropsychiatric symptoms: watch for mood changes or suicidal ideation.
  • Assess liver function: periodic testing is advised in patients with hepatic disease.
  • Use caution in severe asthma: ensure patients have a rescue inhaler.
  • Review concomitant medications: check for potential drug interactions.
  • Store at room temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Montelukast may interact with other medicines, requiring attention to avoid reduced efficacy or increased toxicity.

Major Interactions (Avoid)

  • Strong CYP3A4 inducers (e.g., rifampin): may lower montelukast levels.
  • Phenobarbital: can decrease therapeutic effect.
  • St. John’s wort: may reduce drug exposure.

Moderate Interactions (Monitor Closely)

  • Antidepressants (SSRIs, SNRIs): potential for additive neuropsychiatric effects.
  • Antifungal azoles (ketoconazole): may increase plasma concentrations.
  • Warfarin: monitor INR for possible anticoagulant effect changes.

Frequently Asked Questions

Montelucaste Tecnigen contains montelukast, which is prescribed for maintenance therapy of asthma, relief of seasonal or perennial allergic rhinitis, and prevention of exercise‑induced bronchoconstriction. It helps control airway inflammation and nasal symptoms in both adults and children.

Montelukast blocks the cysteinyl leukotriene receptor CysLT1, preventing leukotrienes D4, E4 and related molecules from binding. This inhibition reduces bronchoconstriction, mucus production, and inflammation in the airways and nasal passages, improving breathing and reducing allergic symptoms.

The appropriate dose of Montelucaste Tecnigen is determined by the prescribing healthcare professional based on the patient’s age, weight, condition severity, and response to therapy. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for montelukast in pregnancy and lactation are limited. Healthcare providers weigh potential benefits against possible risks before prescribing it to pregnant or nursing women. Patients should discuss their individual situation with their doctor.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Montelukast belongs to the leukotriene receptor antagonist class, offering an oral alternative to inhaled corticosteroids or long‑acting beta‑agonists. It is particularly useful for patients with aspirin‑sensitive asthma or those who prefer a once‑daily tablet, though it may be used in combination with other controller medications for optimal control.

Montelucaste Tecnigen tablets should be stored at room temperature, below 25 °C, in the original packaging to protect them from moisture and light. Keep the container tightly closed and out of reach of children.

The medication is taken orally, usually once daily in the evening, with or without food. Swallow the tablet whole with a glass of water and follow the dosing schedule prescribed by the healthcare professional.

Serious but rare risks include severe allergic reactions such as angioedema or anaphylaxis, neuropsychiatric events like depression or suicidal thoughts, and rare skin conditions such as Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they experience any of these symptoms.

Montelucaste Tecnigen is contraindicated in patients with known hypersensitivity to montelukast or any of the tablet’s excipients. It should be used with caution in individuals with severe liver impairment or those taking interacting medications, and it is not recommended for patients with uncontrolled severe asthma without a rescue inhaler.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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