Product image of Montelucaste Teva (Montelukast Sodium) supplied by GNH India

Montelucaste Teva

Active Ingredient:
Montelukast Sodium
Origin:
EU

Montelucaste Teva (Montelukast Sodium)

Montelukast Sodium, the active ingredient in Montelucaste Teva, is a leukotriene receptor antagonist presented as an oral tablet for oral use. It is indicated for maintenance treatment of asthma, relief of allergic rhinitis symptoms, and prevention of exercise‑induced bronchoconstriction in patients who require long‑term control.

GNH India supplies Montelucaste Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva Pharma – Produtos Farmacêuticos Lda

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Indications & Clinical Uses

Montelucaste Teva, a leukotriene receptor antagonist, is used to manage conditions driven by cysteinyl leukotriene activity.

  • Asthma (maintenance therapy): improves long‑term control and reduces exacerbations.
  • Allergic rhinitis: alleviates nasal congestion, sneezing and itching.
  • Exercise‑induced bronchoconstriction: prevents airway narrowing triggered by physical activity.

How It Works

  • Montelukast Sodium selectively blocks the cysteinyl leukotriene receptor CysLT1 on airway smooth muscle and inflammatory cells. By antagonizing this receptor, it inhibits the actions of leukotrienes D4, E4 and related mediators, reducing bronchoconstriction, mucus secretion, vascular permeability, and eosinophilic inflammation that contribute to asthma and allergic airway disease.

Side Effects

Montelucaste Teva is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Abdominal pain or dyspepsia.
  • Cough or throat irritation.
  • Nasopharyngitis (common cold‑like symptoms).
  • Dizziness or somnolence.
  • Mild rash or itching.

Serious or Rare Side Effects

  • Anaphylaxis or severe allergic reactions.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Hepatotoxicity: elevated liver enzymes.
  • Neuropsychiatric events: agitation, depression, or suicidal thoughts.
  • Angioedema: swelling of lips, tongue or face.
  • Hematologic abnormalities: eosinophilia or neutropenia.

Precautions & Warnings

Before initiating therapy, clinicians should consider several safety aspects.

  • Hypersensitivity: avoid in patients with known allergy to montelukast or any tablet excipients.
  • Hepatic impairment: monitor liver function tests in patients with existing liver disease.
  • Pregnancy: use only if the potential benefit justifies the potential risk, as safety data are limited.
  • Pediatric use: dose selection must follow prescriber guidance based on age and weight.
  • Drug interactions: review concomitant medications for possible pharmacokinetic effects.
  • Store at ambient temperature: keep below 25°C in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Montelucast Teva may interact with other medicines that affect its metabolism or pharmacodynamic profile.

Major Interactions (Avoid)

  • Strong CYP3A4 inducers (e.g., rifampin, carbamazepine, phenytoin): may reduce montelukast exposure and efficacy.
  • Concomitant use with other leukotriene modifiers (e.g., zafirlukast): increased risk of adverse effects.

Moderate Interactions (Monitor Closely)

  • Warfarin: potential alteration of anticoagulant effect; monitor INR.
  • Oral contraceptives: may slightly increase plasma levels of estrogen components.
  • Phenobarbital: may modestly lower montelukast concentrations.
  • Ritonavir or other protease inhibitors: may increase montelukast levels, watch for side effects.

Frequently Asked Questions

Montelucaste Teva contains montelukast sodium, a leukotriene receptor antagonist that is prescribed for maintenance therapy of asthma, relief of symptoms associated with allergic rhinitis, and prevention of exercise‑induced bronchoconstriction. These indications reflect its ability to block leukotriene‑mediated airway inflammation and constriction.

Montelukast sodium selectively blocks the cysteinyl leukotriene receptor CysLT1 on airway smooth muscle and inflammatory cells. By preventing leukotrienes D4, E4 and related mediators from binding, it reduces bronchoconstriction, mucus production, vascular leakage, and eosinophilic inflammation that underlie asthma and allergic airway disease.

The specific dose of Montelucaste Teva is determined by the prescribing clinician based on the patient’s age, weight, disease severity, and therapeutic goals. Healthcare professionals follow approved labeling and clinical guidelines to select an appropriate regimen for each individual.

Safety data for montelukast in pregnancy are limited, and the product is classified as having an unknown pregnancy category. It should only be used if the potential benefit outweighs any possible risk. Limited information is available for lactation; therefore, a prescriber should evaluate the risk‑benefit ratio before recommending use while breastfeeding.

To request Montelucaste Teva, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any temperature‑controlled requirements) and necessary import documentation.

Montelucaste Teva belongs to the leukotriene receptor antagonist class, offering an oral, once‑daily option that targets leukotriene‑mediated inflammation. Unlike inhaled corticosteroids or long‑acting β2‑agonists, it does not provide immediate bronchodilation but is useful as an add‑on or maintenance therapy, especially for patients with aspirin‑exacerbated respiratory disease or those preferring oral medication.

Montelucaste Teva should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original blister pack or container, protect them from moisture, excessive heat and direct sunlight to maintain product stability throughout its shelf life.

Montelucaste Teva is taken orally, usually as a whole tablet with or without food. The exact timing (e.g., morning or evening) and frequency are set by the prescriber based on the patient’s therapeutic plan and any concomitant medications.

Serious adverse events, although rare, include severe allergic reactions such as anaphylaxis, skin conditions like Stevens‑Johnson syndrome, hepatotoxicity indicated by elevated liver enzymes, and neuropsychiatric effects such as depression, agitation or suicidal thoughts. Patients should be instructed to seek immediate medical attention if any of these symptoms develop.

Montelucaste Teva is contraindicated in individuals with known hypersensitivity to montelukast sodium or any of the tablet’s inactive ingredients. Caution is also advised for patients with severe hepatic impairment, and it should be avoided in those who have experienced serious allergic reactions to other leukotriene‑modifying agents.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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