Product image of Montelukast För Barn Från 2 Till 5 År Accord (Montelukast) supplied by GNH India

Montelukast För Barn Från 2 Till 5 År Accord

Active Ingredient:
Montelukast
Origin:
EU

Montelukast För Barn Från 2 Till 5 År Accord (Montelukast)

Montelukast, the active ingredient in Montelukast För Barn Från 2 Till 5 År Accord, is a leukotriene receptor antagonist presented as an oral formulation for use in children aged two to five years. It is indicated for the prophylaxis and chronic treatment of asthma, prevention of exercise‑induced bronchoconstriction, and symptomatic relief of allergic rhinitis.

GNH India supplies Montelukast För Barn Från 2 Till 5 År Accord as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Accord Healthcare B.V.

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Indications & Clinical Uses

Montelukast acts on leukotriene pathways that contribute to airway inflammation and allergic symptoms. It is used for several paediatric respiratory conditions:

  • Asthma: provides prophylaxis and chronic control of symptoms in children 2‑5 years old.
  • Exercise‑induced bronchoconstriction: helps prevent airway narrowing triggered by physical activity.
  • Allergic rhinitis: relieves nasal congestion, sneezing and itching associated with seasonal or perennial allergies.

How It Works

  • Montelukast selectively blocks the cysteinyl leukotriene receptor CysLT1 on airway smooth muscle and inflammatory cells. By antagonising this receptor, it inhibits leukotriene‑mediated bronchoconstriction, mucus secretion, and vascular permeability, thereby reducing airway inflammation and improving respiratory function in susceptible children.

Side Effects

Montelukast is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Headache: mild to moderate discomfort.
  • Abdominal pain: occasional stomach upset.
  • Cough: transient irritation of the throat.
  • Sore throat: mild irritation.
  • Nausea: occasional feeling of queasiness.
  • Diarrhoea: loose stools.

Serious or Rare Side Effects

  • Allergic reactions: rash, angioedema, or anaphylaxis.
  • Mood changes: agitation, anxiety, or depressive symptoms.
  • Suicidal thoughts: rare but reported ideation.
  • Hepatic enzyme elevation: abnormal liver function tests.
  • Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.

Precautions & Warnings

When prescribing Montelukast for young children, several safety considerations are recommended.

  • Age limitation: use only in children aged 2‑5 years as indicated.
  • Hepatic impairment: exercise caution and monitor liver function.
  • Concomitant asthma therapy: ensure compatibility with inhaled corticosteroids or bronchodilators.
  • Psychiatric monitoring: observe for mood swings or behavioral changes.
  • Pregnancy and lactation: discuss potential risks with a healthcare professional.
  • Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Montelukast may interact with other medicines that affect its metabolism or therapeutic response.

Major Interactions (Avoid)

  • Phenobarbital: induces hepatic enzymes, reducing montelukast levels.
  • Rifampin: strong enzyme inducer that may lower efficacy.
  • Ketoconazole: potent CYP3A4 inhibitor, potentially increasing exposure.

Moderate Interactions (Monitor Closely)

  • Warfarin: may alter anticoagulant effect; monitor INR.
  • Theophylline: possible additive bronchodilator effect.
  • Beta‑agonists: monitor for enhanced bronchodilation and side‑effects.

Frequently Asked Questions

Montelukast För Barn Från 2 Till 5 År Accord is a leukotriene receptor antagonist indicated for the prophylaxis and chronic treatment of asthma, prevention of exercise‑induced bronchoconstriction, and symptomatic relief of allergic rhinitis in children aged two to five years.

Montelukast selectively blocks the cysteinyl leukotriene receptor CysLT1 on airway smooth muscle and inflammatory cells. This inhibition prevents leukotriene‑mediated bronchoconstriction, mucus production, and vascular leakage, thereby reducing airway inflammation and improving breathing in susceptible children.

The appropriate dose of Montelukast for children aged two to five years is determined by the prescribing healthcare professional based on the child's weight, age, and clinical condition. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety of Montelukast during pregnancy or lactation has not been fully established. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using the medication.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.

Montelukast works by blocking leukotriene receptors, whereas inhaled corticosteroids reduce airway inflammation through a different pathway. Montelukast is often used as an add‑on therapy or alternative in patients who cannot tolerate steroids, but inhaled corticosteroids remain the first‑line treatment for persistent asthma in most guidelines.

Montelukast För Barn Från 2 Till 5 År Accord should be stored at room temperature, below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed when not in use.

Montelukast is taken orally, usually as a chewable tablet or oral granule that can be mixed with a small amount of food or liquid. The exact form and administration instructions are provided by the prescriber, and the dose should be given at the same time each day.

Serious risks include rare allergic reactions such as rash, angioedema, or anaphylaxis, as well as neuropsychiatric events like mood changes, agitation, depression, or suicidal thoughts. Any signs of these reactions require immediate medical attention.

Children younger than two years, patients with known hypersensitivity to Montelukast or any component of the formulation, and individuals with severe hepatic impairment should not use this product unless specifically advised by a qualified healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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