Product image of Montelukast Für Kinder Im Alter Von 2 Bis 5 Jahren Eurogenerics (Montelukast) supplied by GNH India

Montelukast Für Kinder Im Alter Von 2 Bis 5 Jahren Eurogenerics

Active Ingredient:
Montelukast
Origin:
EU

Montelukast Für Kinder Im Alter Von 2 Bis 5 Jahren Eurogenerics (Montelukast)

Montelukast, the active ingredient in Montelukast Für Kinder Im Alter Von 2 Bis 5 Jahren Eurogenerics, is a leukotriene receptor antagonist presented as an oral tablet for oral use. It is indicated for managing asthma and allergic rhinitis in children aged two to five years.

GNH India supplies Montelukast Für Kinder Im Alter Von 2 Bis 5 Jahren Eurogenerics as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The product complies with EU regulatory standards and is manufactured under GMP conditions.

Manufacturer / TM Owner

Eurogenerics N.V./S.A.

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Indications & Clinical Uses

Montelukast is a leukotriene receptor antagonist used to treat respiratory and allergic conditions.

  • Asthma: improves control and reduces frequency of asthma attacks in children.
  • Exercise‑induced bronchospasm: prevents bronchoconstriction triggered by physical activity.
  • Allergic rhinitis: relieves nasal congestion, sneezing and itching associated with seasonal allergies.

How It Works

  • Montelukast selectively blocks cysteinyl leukotriene (CysLT1) receptors in the airways and nasal passages. By antagonizing these receptors, it inhibits the actions of leukotrienes D4, E4 and related mediators that cause bronchoconstriction, mucus secretion, vascular permeability and inflammatory cell recruitment, thereby reducing airway inflammation and hyper‑responsiveness.

Side Effects

Montelukast may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Headache
  • Abdominal pain
  • Cough
  • Nausea

Serious or Rare Side Effects

  • Allergic reactions such as rash, angioedema or anaphylaxis
  • Neuropsychiatric events including agitation, depression or suicidal thoughts
  • Hepatic enzyme elevation or liver injury
  • Severe skin reactions such as Stevens‑Johnson syndrome

Precautions & Warnings

When prescribing Montelukast for children, several precautions should be observed.

  • Age limitation: use is approved for children aged 2‑5 years as indicated.
  • Contraindication: avoid in patients with known hypersensitivity to montelukast or any formulation components.
  • Neuropsychiatric monitoring: observe for mood changes, anxiety or behavioral disturbances.
  • Drug interaction review: assess concomitant medications that may alter montelukast metabolism.
  • Pregnancy and lactation: safety has not been established; use only if potential benefit justifies the risk.
  • Store at ambient temperature: keep below 25 °C in the original packaging, protected from moisture.

Avoid Interactions

Montelukast can interact with other medicines, affecting its efficacy or safety.

Major Interactions (Avoid)

  • Phenobarbital: induces hepatic enzymes, reducing montelukast plasma levels.
  • Rifampin: strong enzyme inducer that may decrease therapeutic effect.
  • Carbamazepine: increases metabolism leading to lower exposure.
  • St. John’s Wort: herbal inducer that can lower montelukast concentrations.

Moderate Interactions (Monitor Closely)

  • Warfarin: montelukast may alter INR, requiring coagulation monitoring.
  • Beta‑agonists: combined use may enhance bronchodilator effects.
  • ACE inhibitors: rare reports of increased bronchospasm when co‑administered.
  • Oral contraceptives: possible reduction in hormonal efficacy, monitor cycle.

Frequently Asked Questions

Montelukast Für Kinder Im Alter Von 2 Bis 5 Jahren Eurogenerics is a leukotriene receptor antagonist indicated for the prophylactic treatment of asthma, the prevention of exercise‑induced bronchospasm, and the relief of symptoms of allergic rhinitis in children aged two to five years.

Montelukast works by selectively blocking cysteinyl leukotriene (CysLT1) receptors in the respiratory tract. This inhibition prevents leukotriene‑mediated bronchoconstriction, mucus production, vascular leakage and inflammatory cell recruitment, leading to improved airway patency and reduced allergic inflammation.

The appropriate dose for a child aged 2‑5 years is determined by the prescribing clinician based on the child’s weight, severity of disease and current clinical guidelines. The prescriber will select the specific tablet strength and dosing frequency that best matches the individual patient’s needs.

Safety data for Montelukast in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision should be made in consultation with a qualified healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Montelukast and inhaled corticosteroids act via different mechanisms; montelukast blocks leukotriene receptors, while inhaled corticosteroids reduce broad airway inflammation. Montelukast is often used as an add‑on therapy or for patients who cannot tolerate steroids, but it is not a direct substitute for the anti‑inflammatory potency of inhaled corticosteroids.

Montelukast tablets should be stored at ambient temperature, preferably below 25 °C, in the original container to protect them from moisture and light. Keep the product out of reach of children and do not use if the packaging is damaged or the tablets appear discoloured.

Montelukast is taken orally, usually once daily in the evening, with or without food. The tablet is swallowed whole; it is not intended to be chewed, crushed or dissolved unless a specific formulation for that purpose is prescribed.

Serious risks include allergic reactions such as rash, angioedema or anaphylaxis, neuropsychiatric events like agitation, depression or suicidal thoughts, liver enzyme elevations indicating possible hepatic injury, and rare severe skin reactions such as Stevens‑Johnson syndrome. Any of these symptoms should prompt immediate medical evaluation.

Montelukast should not be used by individuals with a known hypersensitivity to the drug or any of its excipients. It is also contraindicated in children outside the approved age range (under 2 years or over 5 years for this specific pediatric formulation) unless directed by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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