Product image of Montelukast Voor Pediatrische Patiënten Van 2 Tot 5 Jaar Accord (Montelukast) supplied by GNH India

Montelukast Voor Pediatrische Patiënten Van 2 Tot 5 Jaar Accord

Active Ingredient:
Montelukast
Origin:
EU

Montelukast Voor Pediatrische Patiënten Van 2 Tot 5 Jaar Accord (Montelukast)

Montelukast, the active ingredient in Montelukast Voor Pediatrische Patiënten Van 2 Tot 5 Jaar Accord, is a leukotriene receptor antagonist presented as an oral formulation for oral use. It is indicated for the management of asthma and allergic rhinitis in children aged two to five years.

GNH India supplies Montelukast Voor Pediatrische Patiënten Van 2 Tot 5 Jaar Accord as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide and healthcare providers across multiple continents and regions.

Manufacturer / TM Owner

Accord Healthcare B.V.

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Indications & Clinical Uses

Montelukast acts on leukotriene pathways to control chronic airway inflammation and allergic symptoms. It is clinically employed for the following indications:

  • Asthma: improves symptom control and reduces the frequency of exacerbations in children.
  • Allergic rhinitis: relieves nasal congestion, sneezing, itching and rhinorrhoea.
  • Exercise‑induced bronchospasm: prevents bronchoconstriction triggered by physical activity.

How It Works

  • Montelukast selectively blocks the cysteinyl leukotriene receptor type 1 (CysLT1) on airway smooth muscle and inflammatory cells. By antagonising this receptor, it inhibits leukotriene‑mediated bronchoconstriction, mucus secretion, vascular permeability and eosinophilic inflammation, thereby improving airway patency and reducing allergic inflammation.

Side Effects

Montelukast is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Headache: mild to moderate headache reported.
  • Abdominal pain: occasional stomach discomfort.
  • Cough: transient cough may appear.
  • Nausea: occasional feeling of nausea.
  • Sore throat: mild irritation of the throat.
  • Fever: low‑grade fever in some patients.

Serious or Rare Side Effects

  • Allergic reactions: rash, angioedema or anaphylaxis.
  • Neuropsychiatric events: mood changes, agitation or suicidal thoughts.
  • Hepatic enzyme elevation: rare increase in liver function tests.
  • Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.

Precautions & Warnings

Before prescribing Montelukast, consider the following safety measures:

  • Age limitation: use only in children 2–5 years as directed by a prescriber.
  • Renal or hepatic impairment: monitor liver and kidney function if disease is present.
  • Concomitant asthma therapy: continue inhaled corticosteroids or bronchodilators as needed.
  • Pregnancy: category B; discuss potential risks with the obstetrician.
  • Adherence: do not discontinue abruptly without medical advice.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging and protect from moisture.

Avoid Interactions

Montelukast may interact with other medicines; review the following categories.

Major Interactions (Avoid)

  • Ritonavir: can increase montelukast plasma concentrations.
  • Phenobarbital, carbamazepine, phenytoin: strong enzyme inducers that may reduce efficacy.
  • Strong CYP3A4 inducers: may lower therapeutic levels.

Moderate Interactions (Monitor Closely)

  • Antidepressants (e.g., fluoxetine): monitor for neuropsychiatric effects.
  • Warfarin: observe INR values for potential alteration.
  • Short‑acting β2‑agonists: assess asthma control when used together.

Frequently Asked Questions

Montelukast Voor Pediatrische Patiënten Van 2 Tot 5 Jaar Accord is a prescription medicine that helps control asthma symptoms, reduces the frequency of asthma attacks, and relieves allergic rhinitis signs such as nasal congestion and sneezing in children aged two to five years.

Montelukast works by selectively blocking the cysteinyl leukotriene receptor type 1 (CysLT1). This inhibition prevents leukotrienes from causing bronchoconstriction, airway swelling, and mucus production, thereby improving breathing and decreasing allergic inflammation.

The appropriate dose for each child is determined by the prescribing healthcare professional based on the child’s age, weight, and clinical condition. Parents and caregivers should follow the prescriber’s instructions and not adjust the dose on their own.

Montelukast is classified as pregnancy category B, indicating that animal studies have not shown risk but there are limited human data. It may be used during breastfeeding if the prescriber judges the benefit outweighs any potential risk to the infant.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Montelukast is a leukotriene receptor antagonist that targets a different inflammatory pathway than inhaled corticosteroids, which act on a broad range of inflammatory mediators. Montelukast is often used as an add‑on therapy or for patients who cannot tolerate steroids, but it does not replace the anti‑inflammatory effect of inhaled corticosteroids in moderate‑to‑severe asthma.

Store Montelukast tablets or oral suspension at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and discard any medication that appears discoloured or past its expiry date.

Montelukast is taken orally, usually once daily in the evening. The tablet can be swallowed whole or, if a chewable or liquid form is supplied, administered according to the prescriber’s instructions. It should be taken with or without food as directed.

Serious risks include rare allergic reactions such as angioedema or anaphylaxis, neuropsychiatric events like mood changes or suicidal thoughts, and severe skin reactions such as Stevens‑Johnson syndrome. Caregivers should seek immediate medical attention if any of these symptoms occur.

Montelukast should not be used in children younger than two years, in patients with known hypersensitivity to montelukast or any component of the formulation, and it should be avoided in individuals with a history of severe allergic reactions to leukotriene‑modifying agents.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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