Product image of Montelukast Almus (Montelukast) supplied by GNH India

Montelukast Almus

Active Ingredient:
Montelukast
Origin:
EU

Montelukast Almus (Montelukast)

Montelukast, the active ingredient in Montelukast Almus, is a leukotriene receptor antagonist presented as an oral tablet for oral use. It is used to manage asthma and allergic rhinitis in both adult and pediatric patients.
GNH India supplies Montelukast Almus as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Almus Farmaceutica S.A.

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Indications & Clinical Uses

Montelukast acts on the leukotriene pathway to control chronic respiratory conditions.

  • Asthma (maintenance therapy): improves long‑term control of symptoms and reduces exacerbations.
  • Allergic rhinitis (seasonal or perennial): relieves nasal congestion, sneezing and itching.
  • Exercise‑induced bronchoconstriction: helps prevent airway narrowing during physical activity.

How It Works

  • Montelukast selectively blocks the cysteinyl leukotriene (CysLT1) receptor, preventing leukotrienes D4, E4 and related mediators from binding. This inhibition reduces bronchial smooth‑muscle contraction, vascular permeability, and inflammatory cell recruitment in the airways, thereby improving respiratory function and decreasing allergic inflammation.

Side Effects

Montelukast is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Headache: mild to moderate pain often reported.
  • Abdominal pain: discomfort in the stomach area.
  • Cough: occasional irritation of the throat.
  • Dyspepsia: indigestion or upset stomach.
  • Fatigue: feeling unusually tired.
  • Nausea: sensation of needing to vomit.

Serious or Rare Side Effects

  • Allergic reactions: rash, angioedema, or anaphylaxis.
  • Neuropsychiatric events: depression, mood changes, or suicidal thoughts.
  • Hepatic enzyme elevation: abnormal liver function tests.
  • Neutropenia: reduced white blood cell count.
  • Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.

Precautions & Warnings

Before initiating Montelukast, consider the following safety measures.

  • Assess asthma control: ensure patient is stable on current therapy.
  • Monitor neuropsychiatric symptoms: watch for mood changes or depression.
  • Use caution in hepatic impairment: adjust use if liver disease is present.
  • Avoid in known hypersensitivity: discontinue if allergic reaction occurs.
  • Not for acute asthma attacks: do not replace rescue inhalers.
  • Store at ambient temperature: keep in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Montelukast may interact with other medicines; review patient medication lists.

Major Interactions (Avoid)

  • Strong CYP3A4 inducers (e.g., rifampin, carbamazepine): may markedly reduce Montelukast exposure.
  • Concurrent leukotriene modifiers (e.g., zafirlukast, zileuton): increase risk of adverse effects.

Moderate Interactions (Monitor Closely)

  • Antidepressants (e.g., fluoxetine, sertraline): may heighten neuropsychiatric risk.
  • Theophylline: additive bronchodilator effect may require dose adjustment.
  • Antihistamines: potential for increased sedation.
  • Warfarin: possible alteration of anticoagulant effect, monitor INR.

Frequently Asked Questions

Montelukast Almus is prescribed for the long‑term management of asthma, for relief of symptoms associated with allergic rhinitis, and to prevent exercise‑induced bronchoconstriction. It works by reducing airway inflammation and narrowing, helping patients achieve better respiratory control.

Montelukast blocks the cysteinyl leukotriene (CysLT1) receptor, preventing leukotrienes D4, E4 and related compounds from triggering inflammation, bronchial smooth‑muscle contraction, and mucus production. This receptor antagonism reduces airway swelling and improves breathing.

The specific dose of Montelukast Almus is determined by the prescribing clinician based on the patient’s age, condition severity, and response to therapy. Healthcare providers set the appropriate regimen and adjust it as needed.

Safety data for Montelukast Almus in pregnancy and lactation are limited. The medication should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Montelukast belongs to the leukotriene receptor antagonist class, offering an oral alternative to inhaled corticosteroids or long‑acting beta‑agonists. It is especially useful for patients who prefer oral therapy or have difficulty using inhalers, though it is typically used as add‑on therapy rather than a sole rescue medication.

Montelukast Almus should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight and extreme heat to maintain its stability and potency.

Montelukast Almus is taken orally, usually once daily, with or without food. The tablet should be swallowed whole with a glass of water and not chewed or crushed, unless otherwise instructed by a healthcare professional.

Serious risks include rare allergic reactions such as angioedema or anaphylaxis, and neuropsychiatric events like depression, mood changes, or suicidal thoughts. Patients should seek immediate medical attention if they experience any severe rash, breathing difficulty, or significant changes in mood.

Montelukast Almus should be avoided in individuals with known hypersensitivity to Montelukast or any component of the formulation. It is also not suitable for treating acute asthma attacks, and patients with uncontrolled severe liver disease should use it only under close medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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