Product image of Montelukast Amarox (Montelukast) supplied by GNH India

Montelukast Amarox

Active Ingredient:
Montelukast
Origin:
EU

Montelukast Amarox (Montelukast)

Montelukast, the active ingredient in Montelukast Amarox, is a leukotriene receptor antagonist presented as an oral tablet for oral use. It is prescribed to manage asthma, allergic rhinitis, and exercise‑induced bronchoconstriction in adults and children.

GNH India supplies Montelukast Amarox as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring consistent quality and regulatory compliance across global markets.

Manufacturer / TM Owner

Amarox Limited

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Indications & Clinical Uses

  • Montelukast is a leukotriene receptor antagonist used to treat conditions mediated by leukotriene‑driven inflammation.
  • Asthma: improves control and reduces frequency of bronchospasm.
  • Allergic rhinitis: relieves nasal congestion, sneezing and itching.
  • Exercise‑induced bronchoconstriction: prevents airway narrowing triggered by physical activity.

How It Works

  • Montelukast selectively blocks the cysteinyl leukotriene receptor CysLT1, preventing leukotriene D4 from binding. This inhibition reduces bronchoconstriction, vascular permeability, and inflammatory cell recruitment in the airways, thereby mitigating asthma and allergic symptoms.

Side Effects

Montelukast is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Abdominal pain: occasional discomfort.
  • Cough: transient irritation.
  • Dizziness: occasional light‑headedness.

Serious or Rare Side Effects

  • Allergic reactions: rash, angioedema, or anaphylaxis.
  • Mood changes: depression, anxiety, or suicidal thoughts.
  • Liver enzyme elevation: abnormal hepatic function tests.

Precautions & Warnings

Montelukast should be used with awareness of specific safety considerations.

  • Pregnancy: consult a healthcare provider as safety data are limited.
  • Breastfeeding: use only if the benefit outweighs potential risk.
  • Drug interactions: review all concomitant medications for possible effects.
  • Renal/hepatic impairment: dose may need adjustment based on clinical judgment.
  • Age considerations: safety in children under 12 requires prescriber guidance.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Montelukast may interact with several medicines; monitoring is advised.

Major Interactions (Avoid)

  • Phenobarbital: may reduce montelukast plasma concentrations.
  • Rifampin: may decrease therapeutic effectiveness.
  • Ketoconazole: may increase montelukast levels.

Moderate Interactions (Monitor Closely)

  • Warfarin: potential enhancement of anticoagulant effect.
  • Beta‑agonists: additive bronchodilation may occur.
  • ACE inhibitors: possible increase in cough frequency.

Frequently Asked Questions

Montelukast Amarox contains the active ingredient montelukast, which is indicated for the treatment of asthma, allergic rhinitis, and exercise‑induced bronchoconstriction. It helps control symptoms by reducing airway inflammation and bronchospasm.

Montelukast works by selectively blocking the cysteinyl leukotriene receptor CysLT1. This prevents leukotriene D4 from binding, thereby reducing bronchoconstriction, mucus production, and inflammatory cell recruitment in the respiratory tract.

The appropriate dose of Montelukast Amarox is determined by the prescribing healthcare professional based on the patient’s age, condition, and response to therapy. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for montelukast in pregnancy are limited, so it should be used only if the potential benefit justifies the risk. During breastfeeding, the drug passes into milk in small amounts; use is recommended only when the benefit to the mother outweighs possible risks to the infant.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Montelukast belongs to the leukotriene receptor antagonist class, offering an oral alternative to inhaled corticosteroids or long‑acting beta‑agonists. It is particularly useful for patients with allergic components or exercise‑induced symptoms, but it does not replace rescue bronchodilators for acute attacks.

Store Montelukast Amarox at ambient temperature, preferably below 25 °C. Keep the tablets in the original packaging, protect them from moisture, humidity and direct sunlight to maintain product stability.

Montelukast Amarox is taken orally, usually once daily in the evening, with or without food. The tablet should be swallowed whole with a glass of water; it should not be crushed, chewed, or split unless specifically instructed by a healthcare professional.

Serious risks include allergic reactions such as rash, angioedema, or anaphylaxis, as well as neuropsychiatric events like depression, anxiety, or suicidal thoughts. Any sudden mood changes or severe allergic symptoms should prompt immediate medical attention.

Montelukast is contraindicated in individuals with known hypersensitivity to montelukast or any component of the formulation. Patients with uncontrolled severe liver disease should avoid use, and it should be prescribed with caution in children under the age approved for the specific dosage form.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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