Product image of Montelukast Asthmapharma (Montelukast) supplied by GNH India

Montelukast Asthmapharma

Active Ingredient:
Montelukast
Origin:
EU

Montelukast Asthmapharma (Montelukast)

Montelukast, the active ingredient in Montelukast Asthmapharma, is a leukotriene receptor antagonist presented as an oral dosage form for oral use. It treats asthma and allergic rhinitis in patients requiring chronic management by blocking cysteinyl leukotriene receptors, thereby reducing bronchoconstriction and airway inflammation, and improving symptom control.

GNH India supplies Montelukast Asthmapharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with reliable quality assurance and regulatory compliance, and on‑time delivery to meet global healthcare needs.

Manufacturer / TM Owner

Farmalider, S.A.

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Indications & Clinical Uses

Montelukast, a leukotriene receptor antagonist, is used to manage respiratory allergic conditions.

  • Asthma: improves long‑term control and reduces the frequency of exacerbations.
  • Allergic rhinitis: alleviates nasal congestion, sneezing and itchy eyes.
  • Exercise‑induced bronchoconstriction: prevents airway narrowing during physical activity.

How It Works

  • Montelukast selectively blocks the cysteinyl leukotriene receptor CysLT1 on airway smooth‑muscle cells, mast cells and eosinophils. By preventing leukotriene D4 and related mediators from binding, it inhibits bronchoconstriction, vascular permeability and inflammatory cell recruitment, leading to reduced airway edema and hyper‑responsiveness. The antagonism also diminishes the release of cytokines and reduces mucus secretion, contributing to overall improvement in respiratory function.

Side Effects

Montelukast may cause adverse reactions, which are categorized by frequency.

Common Side Effects

  • Headache: mild to moderate pain in the head.
  • Abdominal pain: discomfort or cramps in the stomach area.
  • Cough: persistent dry cough.
  • Nausea: feeling of sickness or urge to vomit.
  • Dizziness: sensation of light‑headedness or unsteadiness.

Serious or Rare Side Effects

  • Allergic reactions: rash, swelling, angioedema or anaphylaxis.
  • Neuropsychiatric events: mood changes, depression or suicidal thoughts.
  • Hepatic enzyme elevation: increased liver function test results.
  • Blood disorders: eosinophilia, neutropenia or thrombocytopenia.

Precautions & Warnings

Before prescribing Montelukast, clinicians should consider several precautionary measures.

  • Assess asthma control: ensure patient’s asthma is stable before initiating therapy.
  • Monitor neuropsychiatric symptoms: watch for mood changes, depression or suicidal ideation.
  • Use with caution in hepatic impairment: dose adjustment may be required in liver disease.
  • Avoid in known hypersensitivity: discontinue if allergic reaction occurs.
  • Not for acute asthma attacks: should not replace rescue bronchodilators.
  • Store at room temperature: keep in original packaging, protect from moisture and heat.

Avoid Interactions

Montelukast can interact with other medicines, affecting its efficacy or safety.

Major Interactions (Avoid)

  • Phenobarbital: enzyme induction may reduce montelukast plasma levels.
  • Rifampin: strong CYP3A4 inducer can lower drug exposure.
  • Ketoconazole: potent CYP3A4 inhibitor may increase montelukast concentrations.

Moderate Interactions (Monitor Closely)

  • Warfarin: possible alteration of INR, monitor coagulation.
  • Oral contraceptives: montelukast may reduce hormonal efficacy, consider alternative contraception.
  • Beta‑agonists: monitor for additive bronchodilator effects.

Frequently Asked Questions

Montelukast Asthmapharma contains the active ingredient montelukast, a leukotriene receptor antagonist indicated for the long‑term management of asthma and for relieving symptoms of allergic rhinitis. It helps reduce airway narrowing, inflammation and nasal congestion, providing better control of chronic respiratory allergic conditions when used as part of a prescribed treatment plan.

Montelukast selectively blocks the cysteinyl leukotriene receptor CysLT1 on cells of the respiratory tract. By preventing leukotrienes from binding, it inhibits bronchoconstriction, vascular leakage and inflammatory cell recruitment, which together diminish airway edema, mucus production and hyper‑responsiveness, leading to improved breathing and reduced allergic symptoms.

The appropriate dose of Montelukast Asthmapharma is determined by the prescribing healthcare professional based on the patient’s age, weight, severity of disease and other clinical factors. The prescriber will specify the exact strength, frequency and duration of therapy on the prescription label, and patients should follow that guidance without alteration.

Safety data for montelukast in pregnancy and lactation are limited, and the medication should only be used if the potential benefit justifies any possible risk to the fetus or infant. Healthcare providers will evaluate the individual situation and may advise discontinuation or continuation based on current clinical guidelines and the patient’s condition.

To place an order, submit an enquiry on the product page at gnhindia.com, indicating the required quantity of Montelukast Asthmapharma. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Montelukast belongs to the leukotriene receptor antagonist class, offering an oral alternative to inhaled corticosteroids or long‑acting beta‑agonists. It is particularly useful for patients with allergic components, exercise‑induced bronchoconstriction, or those who prefer a once‑daily tablet. While it does not replace rescue bronchodilators, it can complement other controller therapies to achieve better overall asthma control.

Montelukast Asthmapharma should be stored at room temperature, below 25 °C, in its original packaging to protect it from moisture, light and excessive heat. Keep the product out of reach of children and do not use it after the expiration date printed on the label.

The medication is taken orally, usually as a tablet, with or without food as directed by the prescriber. Patients should swallow the tablet whole with a glass of water and follow the dosing schedule indicated on the prescription label, ensuring consistent daily intake for optimal therapeutic effect.

Although uncommon, serious adverse reactions can include severe allergic responses such as angioedema or anaphylaxis, neuropsychiatric events like depression or suicidal thoughts, and significant liver enzyme elevations. Patients should seek immediate medical attention if they experience symptoms such as rash, swelling, mood changes, jaundice or unexplained fatigue.

Montelukast Asthmapharma is contraindicated in individuals with known hypersensitivity to montelukast or any of the tablet’s excipients. It should also be avoided in patients requiring treatment for acute asthma attacks, as it does not provide rapid bronchodilation. Clinicians must assess each patient’s medical history before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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