Product image of Montelukast Aurobindo (Montelukast) supplied by GNH India

Montelukast Aurobindo

Active Ingredient:
Montelukast
Origin:
EU

Montelukast Aurobindo (Montelukast)

Montelukast, the active ingredient in Montelukast Aurobindo, is a leukotriene receptor antagonist presented as an oral tablet for oral use. It treats asthma, allergic rhinitis and exercise‑induced bronchoconstriction in adults and children.

GNH India supplies Montelukast Aurobindo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Puren Pharma Gmbh & Co. Kg

1
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Indications & Clinical Uses

  • Montelukast is a leukotriene receptor antagonist used to manage respiratory allergic conditions.
  • Asthma: reduces frequency of bronchospasm and improves overall disease control.
  • Allergic rhinitis: alleviates nasal congestion, sneezing, itching and rhinorrhea.
  • Exercise‑induced bronchoconstriction: prevents airway narrowing triggered by physical activity.

How It Works

  • Montelukast selectively blocks the cysteinyl leukotriene receptor CysLT1, inhibiting the action of leukotrienes that cause bronchoconstriction, mucus secretion, vascular permeability and inflammatory cell recruitment. By preventing leukotriene‑mediated signaling, it reduces airway inflammation and hyper‑responsiveness associated with asthma and allergic rhinitis.

Side Effects

Montelukast is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Headache
  • Abdominal pain
  • Cough
  • Nausea

Serious or Rare Side Effects

  • Allergic reactions such as rash or angioedema
  • Mood changes including depression or suicidal thoughts
  • Hepatic enzyme elevations

Precautions & Warnings

When prescribing Montelukast, clinicians should consider several safety measures.

  • Monitor liver function: consider periodic testing in patients with hepatic disease.
  • Assess psychiatric status: watch for mood changes, especially in adolescents.
  • Avoid use in patients with known hypersensitivity to montelukast.
  • Use caution in patients with severe renal impairment: dose adjustment may be required.
  • Store at ambient temperature below 25°C: keep in original packaging, protect from moisture.

Avoid Interactions

Montelukast may interact with other medicines; awareness of interaction severity is important.

Major Interactions (Avoid)

  • Phenobarbital: induces hepatic enzymes, reducing montelukast exposure.
  • Rifampin: strong enzyme inducer that may lower therapeutic levels.
  • Ketoconazole: potent CYP3A4 inhibitor that can increase montelukast concentrations.

Moderate Interactions (Monitor Closely)

  • Warfarin: possible alteration of INR; monitor coagulation parameters.
  • Beta‑agonists: additive bronchodilatory effect may require dose adjustment.
  • NSAIDs: may increase risk of gastrointestinal discomfort.

Frequently Asked Questions

Montelukast Aurobindo is prescribed for the management of asthma, allergic rhinitis and exercise‑induced bronchoconstriction. It helps control airway inflammation, reduce bronchospasm frequency and relieve nasal allergy symptoms in both adult and pediatric patients.

Montelukast works by selectively blocking the cysteinyl leukotriene receptor CysLT1. This inhibition prevents leukotrienes from binding to the receptor, thereby reducing bronchoconstriction, mucus production, vascular leakage and inflammatory cell recruitment that contribute to asthma and allergic airway disease.

The dose of Montelukast Aurobindo is determined by the prescribing healthcare professional based on the patient’s age, weight, indication and clinical response. Dosage regimens are individualized and should follow the prescriber’s instructions.

Safety data for Montelukast in pregnancy are limited, and the product is classified as pregnancy category unknown. It should only be used if the potential benefit justifies any potential risk to the fetus. Caution is also advised during breastfeeding, and a clinician should evaluate the risk‑benefit ratio.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Montelukast belongs to the leukotriene receptor antagonist class, offering an oral alternative to inhaled corticosteroids or long‑acting beta‑agonists. It is particularly useful for patients with allergic components, exercise‑induced bronchoconstriction, or those who prefer a once‑daily oral tablet, but it is not a rescue bronchodilator.

Montelukast Aurobindo should be stored at ambient temperature below 25 °C. Keep the tablets in the original packaging, protect them from moisture and direct sunlight, and ensure they are out of reach of children.

Montelukast Aurobindo is taken orally, usually as a tablet, once daily in the evening. The tablet should be swallowed whole with water and not crushed or chewed unless otherwise directed by a healthcare professional.

Serious risks, though rare, include severe allergic reactions such as rash, angioedema or anaphylaxis, and neuropsychiatric events like depression, mood swings or suicidal thoughts. Patients should seek immediate medical attention if they experience any of these symptoms.

Montelukast Aurobindo should be avoided in individuals with a known hypersensitivity to montelukast or any of its excipients. It is also not recommended for patients who require immediate relief of acute bronchospasm, as it does not act as a rescue medication.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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