Product image of Montelukast Aurobindo (Montelukast) supplied by GNH India

Montelukast Aurobindo

Active Ingredient:
Montelukast
Origin:
EU

Montelukast Aurobindo (Montelukast)

Montelukast, the active ingredient in Montelukast Aurobindo, is a leukotriene receptor antagonist presented as an oral tablet for oral use. It is used to manage asthma, allergic rhinitis, and exercise‑induced bronchoconstriction in adults and children as directed by a healthcare professional.

GNH India supplies Montelukast Aurobindo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable sourcing for regulated markets. Our distribution network ensures timely delivery and compliance with local regulatory requirements.

Manufacturer / TM Owner

Aurobindo Pharma (Malta) Limited

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Indications & Clinical Uses

  • Montelukast acts on the leukotriene pathway to control inflammation and bronchoconstriction in several respiratory conditions.
  • Asthma: reduces frequency of wheezing episodes and improves lung function.
  • Allergic rhinitis: alleviates nasal congestion, sneezing and itchy eyes.
  • Exercise‑induced bronchoconstriction: prevents airway narrowing triggered by physical activity.

How It Works

  • Montelukast selectively blocks the cysteinyl leukotriene receptor CysLT1 located on airway smooth‑muscle cells, mast cells and eosinophils. By antagonizing this receptor, it prevents leukotriene‑mediated bronchoconstriction, mucus secretion and inflammatory cell recruitment, thereby reducing airway edema and hyper‑responsiveness associated with asthma and allergic rhinitis. The inhibition is dose‑dependent and contributes to long‑term control of symptoms without causing bronchodilation. Its oral bioavailability allows systemic distribution to target both upper and lower airway tissues.

Side Effects

Montelukast is generally well tolerated, but several adverse reactions have been reported.

Common Side Effects

  • Headache
  • Abdominal pain
  • Cough
  • Nausea

Serious or Rare Side Effects

  • Angioedema or severe allergic reactions
  • Neuropsychiatric events such as agitation, depression, or suicidal thoughts
  • Hepatic injury, including elevated transaminases

Precautions & Warnings

  • Montelukast should be used with careful clinical monitoring.
  • Assess liver function: consider baseline hepatic enzymes before initiating therapy.
  • Monitor neuropsychiatric symptoms: watch for mood changes, anxiety, or suicidal thoughts.
  • Avoid use in patients with known hypersensitivity to montelukast or any tablet excipients.
  • Use caution in severe renal impairment: dose adjustment may be required.
  • Pregnancy and lactation: evaluate risk–benefit ratio as safety data are limited.
  • Store at room temperature: keep in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Montelukast may interact with other medicines that affect its metabolism or pharmacodynamic profile.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ritonavir, ketoconazole): may increase montelukast plasma concentrations.
  • Potent enzyme inducers (e.g., phenobarbital, rifampin): may markedly reduce efficacy.

Moderate Interactions (Monitor Closely)

  • Warfarin: montelukast may potentiate anticoagulant effect; monitor INR.
  • Theophylline: possible additive bronchial effects; observe respiratory status.
  • Beta‑agonists: combined therapy may increase risk of tachycardia.

Frequently Asked Questions

Montelukast Aurobindo is prescribed to treat asthma, allergic rhinitis, and exercise‑induced bronchoconstriction. It helps control airway inflammation and prevent bronchospasm in patients with these respiratory disorders, as determined by a qualified healthcare professional.

Montelukast works by selectively blocking the cysteinyl leukotriene receptor CysLT1 on airway cells. This inhibition prevents leukotriene‑mediated bronchoconstriction, mucus production, and inflammatory cell recruitment, thereby reducing airway swelling and hyper‑responsiveness associated with asthma and allergic conditions.

The dosage of Montelukast Aurobindo is determined by the prescribing clinician based on the patient’s age, weight, severity of disease, and other clinical factors. Only a qualified healthcare provider can set the appropriate dose and dosing schedule.

Safety data for montelukast in pregnancy and lactation are limited. The prescriber should weigh the potential benefits against any possible risks and discuss these considerations with the patient before initiating therapy.

To request Montelukast Aurobindo, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Montelukast belongs to the leukotriene receptor antagonist class, offering an oral option that targets leukotriene‑mediated inflammation. Unlike inhaled corticosteroids or short‑acting bronchodilators, it does not provide immediate bronchodilation but is useful for long‑term control and for patients who cannot tolerate inhaled steroids.

Montelukast Aurobindo tablets should be stored at room temperature, below 25 °C, in the original packaging. Keep them away from moisture, direct sunlight and excessive heat to maintain product stability.

Montelukast Aurobindo is taken orally, usually as a tablet swallowed whole with water. It can be taken with or without food, and the exact timing (e.g., morning or evening) should follow the prescriber’s instructions.

Serious risks include rare but severe allergic reactions such as angioedema, neuropsychiatric events like depression or suicidal thoughts, and hepatic injury. Patients should seek immediate medical attention if they experience swelling of the face or throat, mood changes, or signs of liver dysfunction.

Montelukast Aurobindo should be avoided in individuals with known hypersensitivity to montelukast or any of the tablet’s excipients. It is also contraindicated in patients who have experienced severe allergic reactions to leukotriene receptor antagonists.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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