Product image of Montelukast Aurovitas (Montelukast) supplied by GNH India

Montelukast Aurovitas

Active Ingredient:
Montelukast
Origin:
EU

Montelukast Aurovitas (Montelukast)

Montelukast, the active ingredient in Montelukast Aurovitas, is a leukotriene receptor antagonist presented as an oral tablet for oral use. It treats asthma, allergic rhinitis and exercise‑induced bronchoconstriction in patients requiring leukotriene pathway modulation.

GNH India supplies Montelukast Aurovitas as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Aurovitas Pharma Polska Sp. Z O.O

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Indications & Clinical Uses

  • Montelukast is used to manage respiratory conditions mediated by leukotrienes.
  • Asthma: improves control of chronic asthma and reduces frequency of exacerbations.
  • Allergic rhinitis: relieves nasal congestion, sneezing and itching associated with seasonal allergies.
  • Exercise‑induced bronchoconstriction: prevents narrowing of airways during or after physical activity.

How It Works

  • Montelukast selectively blocks the cysteinyl leukotriene receptor CysLT1 on airway smooth muscle and inflammatory cells. By antagonizing this receptor, it inhibits leukotriene‑induced bronchoconstriction, mucus secretion, and airway inflammation, thereby improving respiratory function and reducing allergic symptoms.

Side Effects

Montelukast may cause a range of adverse reactions, which are categorized by frequency and severity.

Common Side Effects

  • Headache
  • Abdominal pain
  • Cough
  • Nausea
  • Dizziness
  • Fatigue

Serious or Rare Side Effects

  • Allergic reactions such as rash, angioedema, or anaphylaxis
  • Neuropsychiatric events including agitation, depression, or suicidal thoughts
  • Elevated liver enzymes or hepatitis
  • Eosinophilic granulomatosis with polyangiitis
  • Severe skin reactions such as Stevens‑Johnson syndrome
  • Anaphylactic shock

Precautions & Warnings

  • Before prescribing Montelukast, clinicians should consider several safety aspects.
  • Assess patient history: evaluate for prior hypersensitivity to montelukast or similar agents.
  • Monitor for neuropsychiatric symptoms: watch for mood changes, depression, or suicidal thoughts.
  • Consider liver function: check baseline hepatic enzymes in patients with liver disease.
  • Use caution in elderly: adjust monitoring as needed.
  • Avoid use in patients with known hypersensitivity to the drug.
  • Store at below 25°C: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Montelukast can interact with other medicines, requiring attention to avoid reduced efficacy or increased toxicity.

Major Interactions (Avoid)

  • Phenobarbital, rifampin, carbamazepine: may significantly reduce montelukast plasma concentrations.
  • Strong CYP3A4 inhibitors (ketoconazole, itraconazole): may increase exposure, raising risk of adverse effects.
  • Live vaccines: theoretical risk of altered immune response.

Moderate Interactions (Monitor Closely)

  • Other leukotriene modifiers: additive effects on leukotriene pathways.
  • Warfarin: possible alteration of anticoagulant effect.
  • Beta‑agonists: no direct interaction but monitor overall asthma control.

Frequently Asked Questions

Montelukast Aurovitas is prescribed to manage asthma, allergic rhinitis, and exercise‑induced bronchoconstriction. It works by targeting leukotriene pathways that contribute to airway narrowing and inflammation, helping to control symptoms and reduce the frequency of attacks.

Montelukast selectively blocks the cysteinyl leukotriene receptor CysLT1 on airway smooth muscle and inflammatory cells. This inhibition prevents leukotriene‑mediated bronchoconstriction, mucus production, and inflammation, thereby improving breathing and reducing allergic symptoms.

The appropriate dose of Montelukast Aurovitas is determined by the prescribing healthcare professional based on the patient’s age, condition severity, and clinical response. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for Montelukast in pregnancy and lactation are limited. The prescriber will weigh potential benefits against possible risks before recommending use. Women who are pregnant, planning pregnancy, or breastfeeding should discuss their situation with a healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Montelukast belongs to the leukotriene receptor antagonist class, offering an oral alternative to inhaled corticosteroids or long‑acting beta‑agonists. It is particularly useful for patients with aspirin‑sensitive asthma or those who need additional control beyond inhaled therapy, though it is generally not a substitute for rescue inhalers.

Montelukast Aurovitas should be stored at temperatures below 25 °C, in its original packaging, protected from moisture and direct sunlight. Keeping the product in a dry, cool environment helps maintain its stability and potency.

Montelukast Aurovitas is taken orally as a tablet. The tablet should be swallowed whole with water, typically once daily, at the same time each day, unless the prescriber advises a different schedule.

Serious risks include neuropsychiatric events such as depression, agitation, or suicidal thoughts, as well as severe allergic reactions like rash, angioedema, or anaphylaxis. Liver injury and rare eosinophilic conditions have also been reported; patients should seek immediate medical attention if these occur.

Montelukast Aurovitas should be avoided in individuals with known hypersensitivity to montelukast or any component of the formulation. Caution is also advised for patients with a history of severe neuropsychiatric disorders or liver disease, and the drug should be used only under medical supervision in these cases.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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