Product image of Montelukast Dorom (Montelukast Sodium) supplied by GNH India

Montelukast Dorom

Active Ingredient:
Montelukast Sodium
Origin:
EU

Montelukast Dorom (Montelukast Sodium)

Montelukast Sodium, the active ingredient in Montelukast Dorom, is a leukotriene receptor antagonist presented as a tablet for buccal, nasal, cutaneous and dental use. It is used to manage asthma, allergic rhinitis and exercise‑induced bronchospasm in patients requiring anti‑inflammatory therapy.

GNH India supplies Montelukast Dorom as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company follows strict quality standards and provides regulatory‑approved batches to meet global demand.

Manufacturer / TM Owner

Teva Italia S.R.L.

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Indications & Clinical Uses

  • Montelukast Dorom acts on the leukotriene pathway to control inflammatory airway diseases.
  • Asthma: reduces bronchoconstriction and airway inflammation, improving symptom control.
  • Allergic rhinitis: alleviates nasal congestion, sneezing and itching by blocking leukotriene effects.
  • Exercise‑induced bronchospasm: prevents airway narrowing triggered by physical activity, allowing better exercise tolerance.

How It Works

  • Montelukast Sodium selectively antagonizes the cysteinyl leukotriene receptor CysLT1, blocking leukotriene‑mediated bronchoconstriction, mucus secretion, and inflammatory cell recruitment. By inhibiting this pathway, it reduces airway edema and hyperresponsiveness, contributing to improved respiratory function in asthma and allergic conditions.

Side Effects

Montelukast Dorom may cause a range of adverse reactions, varying in frequency and severity.

Common Side Effects

  • Headache
  • Abdominal pain
  • Cough
  • Nasopharyngitis

Serious or Rare Side Effects

  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Angioedema or severe allergic reactions
  • Neuropsychiatric events such as mood changes, depression, or suicidal thoughts

Precautions & Warnings

  • When prescribing Montelukast Dorom, clinicians should consider several precautionary measures to ensure safe use.
  • Assess asthma control before initiation: confirm that baseline therapy is optimized.
  • Monitor for neuropsychiatric events: watch for mood changes, depression or suicidal thoughts.
  • Use caution in hepatic impairment: adjust therapy if liver function is compromised.
  • Avoid in patients with known hypersensitivity to montelukast or excipients: discontinue if reactions occur.
  • Review concomitant medications for potential interactions: adjust doses as needed.
  • Store at below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Montelukast Dorom can interact with other medicines, affecting its efficacy or safety.

Major Interactions (Avoid)

  • Strong CYP3A4 inducers (e.g., rifampin, carbamazepine, phenytoin): may markedly reduce montelukast exposure, compromising therapeutic effect.
  • Concurrent use with other leukotriene pathway inhibitors (e.g., zafirlukast): may increase risk of adverse reactions.

Moderate Interactions (Monitor Closely)

  • Warfarin: montelukast may potentiate anticoagulant effect, requiring INR monitoring.
  • Phenylephrine or other sympathomimetics: may enhance cardiovascular effects, monitor blood pressure.
  • Selective serotonin reuptake inhibitors: potential increase in neuropsychiatric side effects, observe patient.

Frequently Asked Questions

Montelukast Dorom is prescribed to treat asthma, allergic rhinitis, and exercise‑induced bronchospasm. By targeting leukotriene‑mediated inflammation, it helps reduce airway narrowing, nasal congestion, and related symptoms, improving breathing and quality of life for patients with these respiratory conditions.

Montelukast Sodium works as a selective antagonist of the cysteinyl leukotriene receptor CysLT1. By blocking this receptor, it prevents leukotrienes from causing bronchoconstriction, mucus production, and inflammation, thereby easing airway obstruction and allergic responses.

The dose of Montelukast Dorom is determined by the prescribing clinician based on the patient’s age, condition severity, and response to therapy. Healthcare providers follow approved labeling and clinical guidelines to select an appropriate regimen for each individual.

Safety data for Montelukast Dorom in pregnancy and lactation are limited. The medication should only be used if the potential benefit justifies any potential risk to the fetus or infant, and decisions should be made in consultation with a qualified healthcare professional.

To order Montelukast Dorom, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Montelukast belongs to the leukotriene receptor antagonist class, offering an oral alternative to inhaled corticosteroids and bronchodilators. It is particularly useful for patients with aspirin‑sensitive asthma or those who need additional control of allergic symptoms, but it does not replace rescue inhalers for acute bronchospasm.

Montelukast Dorom should be stored at temperatures below 25 °C (77 °F). Keep the tablets in their original packaging, protect them from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability.

Montelukast Dorom is administered orally as a tablet. It can be taken with or without food, typically once daily in the evening, but the exact timing and administration instructions are provided by the prescriber based on individual therapeutic needs.

Serious adverse reactions include severe skin disorders such as Stevens‑Johnson syndrome or toxic epidermal necrolysis, angioedema, and neuropsychiatric events like mood changes, depression, or suicidal thoughts. Patients should seek immediate medical attention if they experience any of these symptoms.

Montelukast Dorom should not be used by individuals with known hypersensitivity to montelukast sodium or any of its excipients. Caution is also advised for patients with severe liver impairment or those taking interacting medications that may alter its effectiveness.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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