Product image of Montelukast Eg (Montelukast) supplied by GNH India

Montelukast Eg

Active Ingredient:
Montelukast
Origin:
EU

Montelukast Eg (Montelukast)

Montelukast, the active ingredient in Montelukast Eg, is a leukotriene receptor antagonist presented as an oral dosage form for systemic use. It is employed to manage asthma and allergic rhinitis, reducing inflammation and bronchoconstriction in patients of various ages. The medication works by blocking specific inflammatory mediators, helping to improve breathing and reduce nasal symptoms.

GNH India supplies Montelukast Eg as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. Our distribution network ensures reliable delivery and adherence to regulatory standards across multiple regions.

Manufacturer / TM Owner

Eg Labo Laboratoires Eurogenerics

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Indications & Clinical Uses

  • Montelukast acts on leukotriene pathways to control respiratory and allergic conditions.
  • Asthma: improves control of persistent asthma and reduces the frequency of exacerbations.
  • Allergic rhinitis: alleviates nasal congestion, sneezing and itching associated with seasonal or perennial allergic rhinitis.
  • Exercise‑induced bronchoconstriction: prevents narrowing of the airways triggered by physical activity.

How It Works

  • Montelukast selectively binds to the cysteinyl leukotriene receptor type 1 (CysLT1) on airway smooth‑muscle cells, mast cells, eosinophils and other inflammatory cells. By blocking the actions of leukotrienes D4, C4 and E4, it prevents the cascade that leads to bronchoconstriction, mucus secretion, vascular permeability and eosinophilic inflammation, thereby stabilising airway tone and reducing allergic responses.

Side Effects

Montelukast may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Headache
  • Abdominal pain
  • Cough
  • Nausea

Serious or Rare Side Effects

  • Allergic reactions such as rash, angioedema or anaphylaxis
  • Mood changes including depression, anxiety or suicidal thoughts
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis

Precautions & Warnings

  • Before initiating therapy, clinicians should consider several safety aspects.
  • Assess asthma control: verify that baseline disease management is optimized.
  • Monitor for neuropsychiatric symptoms: watch for mood changes or suicidal ideation during treatment.
  • Use with caution in hepatic impairment: dose adjustment may be required.
  • Avoid in individuals with known hypersensitivity to montelukast or tablet excipients.
  • Review concomitant medications: assess for potential drug‑drug interactions.
  • Store at below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Montelukast can interact with other medicines, influencing its efficacy or safety.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole) may increase montelukast plasma concentrations.
  • Rifampin or other potent CYP inducers may reduce therapeutic effectiveness.

Moderate Interactions (Monitor Closely)

  • Antidepressants (SSRIs, SNRIs) may augment neuropsychiatric adverse effects.
  • Beta‑agonist bronchodilators may have additive bronchodilatory effect.
  • Warfarin may require INR monitoring due to possible alteration in plasma protein binding.

Frequently Asked Questions

Montelukast Eg is used to treat asthma, allergic rhinitis and to prevent exercise‑induced bronchoconstriction. By targeting leukotriene pathways, it helps reduce airway inflammation, improve breathing, and relieve nasal symptoms associated with allergic conditions.

Montelukast works by selectively blocking the cysteinyl leukotriene receptor type 1 (CysLT1). This inhibition prevents leukotrienes D4, C4 and E4 from triggering bronchoconstriction, mucus production and inflammatory cell activation, thereby stabilising the airways and reducing allergic responses.

The appropriate dose of Montelukast Eg is determined by a qualified healthcare professional based on the patient’s age, condition and response to therapy. Prescribers follow established clinical guidelines and adjust the regimen as needed.

Safety data for Montelukast in pregnancy and lactation are limited. Women who are pregnant, planning pregnancy or breastfeeding should discuss potential risks and benefits with their physician before starting treatment.

To order Montelukast Eg, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Montelukast is an oral leukotriene receptor antagonist, whereas inhaled corticosteroids are anti‑inflammatory agents delivered directly to the lungs. Montelukast is often used as an add‑on therapy or for patients who cannot tolerate inhaled steroids, but it does not replace the anti‑inflammatory potency of corticosteroids in severe asthma.

Montelukast Eg should be stored at temperatures below 25 °C, in its original packaging, and protected from moisture and direct sunlight. Keep the product out of reach of children and avoid exposing it to excessive heat or humidity.

Montelukast Eg is taken orally, usually as a tablet, with or without food. The tablet is swallowed whole with a glass of water. Patients should follow the dosing schedule prescribed by their healthcare provider.

Serious risks include severe allergic reactions such as rash, angioedema or anaphylaxis, neuropsychiatric events like depression or suicidal thoughts, and rare skin conditions such as Stevens‑Johnson syndrome. Any of these symptoms require immediate medical attention.

Montelukast Eg should be avoided in individuals with known hypersensitivity to montelukast or any of the tablet’s excipients. Patients with severe hepatic impairment should use it only under close medical supervision, and it is not recommended for use in children under the age approved for the specific formulation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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