Product image of Montelukast Glenmark (Montelukast Sodium) supplied by GNH India

Montelukast Glenmark

Active Ingredient:
Montelukast Sodium
Origin:
EU

Montelukast Glenmark (Montelukast Sodium)

Montelukast Sodium, the active ingredient in Montelukast Glenmark, is a leukotriene receptor antagonist presented as an oral tablet for oral use. It treats asthma, allergic rhinitis and exercise‑induced bronchoconstriction in adults and children.

GNH India supplies Montelukast Glenmark as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Glenmark Arzneimittel Gmbh

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Indications & Clinical Uses

Montelukast Glenmark, a leukotriene receptor antagonist, is used to manage conditions mediated by cysteinyl leukotrienes.

  • Asthma: improves symptom control and reduces the frequency of wheezing episodes.
  • Allergic rhinitis: relieves nasal congestion, sneezing and itching.
  • Exercise‑induced bronchoconstriction: prevents airway narrowing triggered by physical activity.

How It Works

  • Montelukast Sodium selectively blocks the cysteinyl leukotriene receptor CysLT1, preventing leukotriene D4 and related mediators from binding. This inhibition reduces bronchoconstriction, vascular permeability, mucus secretion, and inflammatory cell recruitment in the airways, thereby improving respiratory function and alleviating allergic inflammation.

Side Effects

Montelukast is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Headache: mild to moderate pain often transient.
  • Abdominal pain: discomfort or cramps in the stomach area.
  • Cough: occasional irritation of the throat.
  • Nausea: feeling of unease or urge to vomit.
  • Sore throat: mild irritation of the pharynx.
  • Dizziness: brief episodes of light‑headedness.

Serious or Rare Side Effects

  • Allergic reactions: rash, angioedema or anaphylaxis.
  • Mood changes: depression, anxiety or suicidal thoughts.
  • Hepatic enzyme elevation: abnormal liver function tests.
  • Stevens‑Johnson syndrome: severe skin and mucous membrane disorder.
  • Anaphylactic shock: rapid onset of severe allergic response.

Precautions & Warnings

When prescribing Montelukast, clinicians should consider several safety measures.

  • Assess liver function: monitor transaminases in patients with hepatic disease.
  • Review psychiatric history: observe for mood alterations or suicidal ideation.
  • Avoid use in patients with known hypersensitivity to montelukast or its excipients.
  • Use with caution in children under 12 for asthma control: follow pediatric dosing guidelines.
  • Store at room temperature: keep in the original pack, protect from moisture and light.

Avoid Interactions

Montelukast may interact with other medicines, requiring attention to potential changes in efficacy or safety.

Major Interactions (Avoid)

  • Ritonavir: may increase montelukast plasma concentrations.
  • Phenobarbital: may reduce montelukast effectiveness.
  • Carbamazepine: may lower drug exposure.

Moderate Interactions (Monitor Closely)

  • Warfarin: possible alteration of INR, requiring coagulation monitoring.
  • Theophylline: monitor for additive bronchospasm risk.

Frequently Asked Questions

Montelukast Glenmark is prescribed to manage asthma, allergic rhinitis and exercise‑induced bronchoconstriction. By blocking leukotriene receptors, it helps reduce airway inflammation, nasal symptoms and prevents narrowing of the airways during physical activity.

Montelukast Sodium selectively antagonizes the cysteinyl leukotriene receptor CysLT1. This blocks leukotriene D4 and related mediators from triggering bronchoconstriction, mucus production, vascular leakage and inflammatory cell recruitment, thereby improving breathing and reducing allergic symptoms.

The appropriate dose of Montelukast Glenmark is determined by the prescribing healthcare professional based on the patient’s age, condition and clinical response. Dosage instructions are provided on the prescription label and should be followed exactly as directed.

The safety of Montelukast during pregnancy or lactation has not been definitively established. Healthcare providers weigh potential benefits against possible risks and may consider alternative therapies when appropriate. Patients should discuss their specific situation with their physician.

To request Montelukast Glenmark, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Montelukast belongs to the leukotriene receptor antagonist class, offering an oral alternative to inhaled corticosteroids or long‑acting beta‑agonists. It is particularly useful for patients with allergic components or exercise‑induced symptoms, whereas inhaled therapies directly target airway inflammation and bronchospasm.

Montelukast Glenmark should be stored at room temperature, below 25 °C, in its original packaging. Protect the tablets from moisture, excessive heat and direct sunlight to maintain potency throughout the shelf life.

Montelukast Glenmark is taken orally, usually as a single tablet each day. It can be swallowed with or without food, according to the prescriber’s instructions. Consistency in timing helps maintain steady drug levels.

Serious risks include severe allergic reactions such as rash, angioedema or anaphylaxis, and neuropsychiatric events like depression, anxiety or suicidal thoughts. Patients should seek immediate medical attention if they experience any of these symptoms.

Montelukast Glenmark is contraindicated in individuals with known hypersensitivity to montelukast sodium or any of its excipients. It should be used with caution in patients with liver disease, psychiatric disorders, or those taking interacting medications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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