Product image of Montelukast Puren (Montelukast) supplied by GNH India

Montelukast Puren

Active Ingredient:
Montelukast
Origin:
EU

Montelukast Puren (Montelukast)

Montelukast, the active ingredient in Montelukast Puren, is a leukotriene receptor antagonist presented as an oral tablet for oral use. It is used to manage asthma, exercise‑induced bronchoconstriction, and allergic rhinitis in adults and children by blocking cysteinyl leukotriene receptors, thereby reducing airway inflammation and bronchoconstriction.

GNH India supplies Montelukast Puren as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Puren Pharma Gmbh & Co. Kg

1
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Indications & Clinical Uses

Montelukast is a leukotriene receptor antagonist used to treat conditions involving airway inflammation and allergic responses.

  • Asthma: Improves control of chronic asthma symptoms and reduces frequency of exacerbations.
  • Exercise‑induced bronchoconstriction: Prevents narrowing of the airways triggered by physical activity.
  • Allergic rhinitis: Relieves nasal congestion, sneezing and itching associated with seasonal allergies.

How It Works

  • Montelukast selectively antagonizes the cysteinyl leukotriene receptor CysLT1, inhibiting leukotriene‑mediated bronchoconstriction, mucus secretion, and inflammatory cell recruitment in the respiratory tract, which helps to maintain airway patency and reduce allergic inflammation.

Side Effects

Montelukast may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Headache: mild to moderate head pain.
  • Upper respiratory infection: sore throat, nasal congestion, or mild cough.
  • Cough: occasional dry or productive cough.
  • Abdominal pain: mild stomach discomfort.

Serious or Rare Side Effects

  • Mood changes: depression, anxiety, or suicidal thoughts.
  • Allergic reactions: rash, hives, or swelling of the face.
  • Liver enzyme elevation: signs of hepatic dysfunction.

Precautions & Warnings

Montelukast should be used with caution in specific clinical situations.

  • Pregnancy: safety not established; use only if benefit outweighs risk.
  • Breastfeeding: unknown; consider potential effects on the infant.
  • Hepatic impairment: monitor liver function and adjust therapy if needed.
  • Concomitant enzyme inducers (e.g., phenobarbital, rifampin): may reduce effectiveness.
  • Age restrictions: not recommended for children under 12 months for asthma treatment.
  • Store at ambient temperature: keep below 25°C, retain in the original pack, and protect from moisture.

Avoid Interactions

Montelukast can interact with other medicines, requiring attention to potential changes in efficacy or safety.

Major Interactions (Avoid)

  • Phenobarbital: induces metabolism, decreasing montelukast levels.
  • Rifampin: strong enzyme inducer that reduces drug exposure.
  • Strong CYP3A4 inhibitors: may increase plasma concentrations.

Moderate Interactions (Monitor Closely)

  • Antidepressants (e.g., SSRIs): possible additive mood‑related effects.
  • Antihistamines: may cause additive sedation in sensitive individuals.
  • Warfarin: potential alteration of INR; monitor coagulation parameters.

Frequently Asked Questions

Montelukast Puren is prescribed to manage chronic asthma, prevent exercise‑induced bronchoconstriction, and relieve symptoms of allergic rhinitis such as nasal congestion, sneezing, and itching.

Montelukast blocks the cysteinyl leukotriene receptor CysLT1, preventing leukotrienes from causing bronchoconstriction, mucus production, and inflammation in the airways, which helps keep breathing easier.

The dosage of Montelukast Puren is determined by the prescribing clinician based on the patient’s age, condition, and response to therapy. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for Montelukast in pregnancy are limited, and it is classified as a drug with unknown pregnancy risk. It is also excreted in breast milk, so use only if the potential benefit justifies any possible risk to the infant.

To place an order, submit an enquiry on the Montelukast Puren product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Montelukast belongs to the leukotriene receptor antagonist class, offering an oral alternative to inhaled corticosteroids or long‑acting bronchodilators. It is particularly useful for patients with aspirin‑sensitive asthma or those who need additional control of allergic components, but it does not replace rescue inhalers for acute attacks.

Montelukast Puren should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid storing in humid or excessively hot environments.

Montelukast Puren is taken orally, usually as a tablet swallowed whole with water. It can be taken with or without food, and the timing (e.g., in the evening) may be recommended by the prescriber based on the specific indication.

Serious risks include mood changes such as depression, anxiety, or suicidal thoughts, as well as rare allergic reactions like rash, hives, or swelling of the face. Any new or worsening psychiatric symptoms should be reported to a healthcare professional immediately.

Montelukast is contraindicated in patients with known hypersensitivity to the drug or any of its excipients. Caution is advised for individuals with severe hepatic impairment, and it is not recommended for children under the approved age for specific indications without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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