Product image of Montelukast Rudipharm (Montelukast Sodium) supplied by GNH India

Montelukast Rudipharm

Active Ingredient:
Montelukast Sodium
Origin:
EU

Montelukast Rudipharm (Montelukast Sodium)

Montelukast Sodium, the active ingredient in Montelukast Rudipharm, is a leukotriene receptor antagonist presented as an oral dosage form for systemic use. It is used to manage asthma, allergic rhinitis and exercise‑induced bronchoconstriction in adults and children.

GNH India supplies Montelukast Rudipharm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality and regulatory compliance across multiple markets. The product meets EU standards and is manufactured under GMP conditions, with rigorous quality testing for patient safety.

Manufacturer / TM Owner

Rudipharm Limited

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Indications & Clinical Uses

Montelukast acts on leukotriene pathways to control airway inflammation and bronchoconstriction.

  • Asthma: reduces frequency of wheezing episodes and improves overall lung function.
  • Allergic rhinitis: alleviates nasal congestion, sneezing and itchy eyes caused by allergens.
  • Exercise‑induced bronchoconstriction: prevents narrowing of airways triggered by physical activity.

How It Works

  • Montelukast selectively blocks the cysteinyl leukotriene receptor CysLT1 on airway smooth‑muscle cells, mast cells and eosinophils. By antagonizing this receptor, it prevents leukotriene‑mediated bronchoconstriction, vascular permeability and inflammatory cell recruitment, thereby reducing airway edema and hyper‑responsiveness associated with asthma and allergic conditions. The inhibition also diminishes the release of pro‑inflammatory cytokines and limits mucus hypersecretion, contributing to improved respiratory symptoms.

Side Effects

Montelukast is generally well tolerated, but several adverse reactions have been reported.

Common Side Effects

  • Headache: mild to moderate pain often transient.
  • Abdominal pain: discomfort or cramps in the stomach area.
  • Nausea: feeling of queasiness, sometimes with vomiting.
  • Diarrhea: loose stools occurring intermittently.

Serious or Rare Side Effects

  • Allergic reactions: rash, urticaria, angioedema, or anaphylaxis.
  • Neuropsychiatric events: mood changes, depression, or suicidal thoughts.
  • Hepatic enzyme elevation: abnormal liver function tests indicating possible liver injury.

Precautions & Warnings

When prescribing Montelukast, clinicians should consider several safety precautions.

  • Assess liver function: evaluate baseline hepatic enzymes in patients with liver disease.
  • Monitor neuropsychiatric status: watch for mood swings, depression or suicidal ideation.
  • Use as maintenance therapy only: it is not intended for acute asthma attacks.
  • Avoid in known hypersensitivity: discontinue immediately if allergic reaction occurs.
  • Store at room temperature: keep in the original packaging, protect from moisture and heat.

Avoid Interactions

Montelukast may interact with other medicines, altering its effectiveness or safety.

Major Interactions (Avoid)

  • Ritonavir: can increase montelukast plasma concentrations.
  • Phenobarbital: may reduce montelukast effectiveness by inducing metabolism.
  • Ketoconazole: may raise montelukast levels, increasing risk of side effects.

Moderate Interactions (Monitor Closely)

  • Warfarin: potential for increased INR, requiring closer monitoring.
  • Beta‑agonists: additive bronchodilatory effect may enhance symptom control.
  • Theophylline: combined use may affect respiratory response, necessitating observation.

Frequently Asked Questions

Montelukast Rudipharm contains the active ingredient Montelukast Sodium and is prescribed to treat asthma, allergic rhinitis and exercise‑induced bronchoconstriction. It works as a maintenance therapy to reduce airway inflammation and prevent bronchospasm in patients with these respiratory conditions.

Montelukast selectively blocks the cysteinyl leukotriene receptor CysLT1 on cells in the respiratory tract. By antagonizing this receptor, it inhibits leukotriene‑mediated bronchoconstriction, vascular leakage and inflammatory cell recruitment, thereby decreasing airway swelling and hyper‑responsiveness.

The appropriate dose of Montelukast is determined by the prescribing healthcare professional based on the patient’s age, condition and clinical response. Dosage regimens may differ for asthma, allergic rhinitis or exercise‑induced bronchoconstriction, and should follow the prescriber’s instructions.

Safety data for Montelukast during pregnancy and lactation are limited. Healthcare providers should weigh the potential benefits against possible risks and discuss any concerns with the patient. Women who are pregnant, planning pregnancy or breastfeeding should consult their physician before using the medication.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity of Montelukast Rudipharm. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Montelukast belongs to the leukotriene receptor antagonist class, offering an oral alternative to inhaled corticosteroids or long‑acting beta‑agonists for maintenance therapy. While inhaled steroids directly reduce airway inflammation, Montelukast provides a convenient once‑daily tablet that specifically blocks leukotriene pathways, which can be advantageous for patients preferring oral medication.

Montelukast Rudipharm should be stored at room temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture, direct sunlight and excessive heat. Do not store in the bathroom or near a kitchen sink where humidity is high.

Montelukast is taken orally, usually as a tablet that should be swallowed whole with water. It is generally taken once daily in the evening, but patients should follow the specific timing advised by their prescriber. The tablet should not be chewed, crushed or split unless directed by a healthcare professional.

Serious adverse events include allergic reactions such as rash, urticaria, angioedema or anaphylaxis, as well as neuropsychiatric effects like mood changes, depression, or suicidal thoughts. Rarely, liver enzyme elevations may occur. Patients should seek immediate medical attention if they experience any of these symptoms.

Montelukast should be avoided in individuals with a known hypersensitivity to Montelukast Sodium or any of the tablet’s excipients. It is also not appropriate as a rescue medication for acute asthma attacks. Patients with severe liver disease or uncontrolled psychiatric conditions should discuss alternative therapies with their clinician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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