Product image of Montelukast Tecnigen (Montelukast) supplied by GNH India

Montelukast Tecnigen

Active Ingredient:
Montelukast
Origin:
EU

Montelukast Tecnigen (Montelukast)

Montelukast, the active ingredient in Montelukast Tecnigen, is a leukotriene receptor antagonist presented as a tablet for oral use. It is indicated for maintenance therapy of asthma, relief of allergic rhinitis symptoms, and prevention of exercise‑induced bronchoconstriction in adults and children.
GNH India supplies Montelukast Tecnigen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Tecnimede España Ind. Fca., S.A.

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Indications & Clinical Uses

Montelukast acts on the leukotriene pathway to control chronic airway disorders.

  • Asthma: reduces frequency of symptoms, nighttime awakenings and exacerbations.
  • Allergic rhinitis: alleviates nasal congestion, sneezing, itching and rhinorrhea.
  • Exercise‑induced bronchoconstriction: prevents airway narrowing triggered by physical activity.

How It Works

  • Montelukast selectively antagonizes the cysteinyl leukotriene receptor CysLT1, blocking the action of leukotriene D4 and related mediators. This inhibition reduces leukotriene‑mediated bronchoconstriction, vascular permeability, and inflammatory cell recruitment in the airways, thereby improving respiratory function and decreasing allergic inflammation.

Side Effects

Montelukast is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Headache
  • Abdominal pain
  • Cough
  • Nausea
  • Dizziness
  • Fatigue

Serious or Rare Side Effects

  • Angioedema
  • Stevens‑Johnson syndrome
  • Eosinophilic pneumonia
  • Hepatic injury
  • Anaphylaxis
  • Mood changes or suicidal thoughts

Precautions & Warnings

Before initiating therapy, consider the following safety points.

  • Pregnancy: Category B; use only if benefit outweighs potential risk.
  • Breastfeeding: Monitor infant; drug may be excreted in milk.
  • Hepatic impairment: Dose may require adjustment; monitor liver function.
  • Concomitant enzyme inducers (e.g., phenobarbital, rifampin) can lower exposure.
  • Not indicated for acute asthma attacks; provide rescue medication separately.
  • Store at ambient temperature: keep below 25°C, retain in original packaging and protect from moisture.

Avoid Interactions

Montelukast may interact with several medicines; review patient medication lists.

Major Interactions (Avoid)

  • Phenobarbital: may markedly reduce plasma concentrations of Montelukast.
  • Rifampin: can lower drug exposure, diminishing therapeutic effect.
  • Strong CYP3A4 inducers (e.g., carbamazepine): may decrease Montelukast levels.

Moderate Interactions (Monitor Closely)

  • Antidepressants (e.g., fluoxetine, sertraline): potential for neuropsychiatric adverse events.
  • Warfarin: possible alteration of INR; monitor coagulation parameters.
  • Antihistamines: may add to sedation or anticholinergic load; observe patient response.

Frequently Asked Questions

Montelukast Tecnigen is prescribed for the long‑term management of asthma, to relieve symptoms of seasonal or perennial allergic rhinitis, and to prevent exercise‑induced bronchoconstriction. It works as a maintenance therapy and is not intended for immediate relief of acute asthma attacks.

Montelukast blocks the cysteinyl leukotriene receptor CysLT1, preventing leukotrienes from binding and triggering bronchoconstriction, airway edema, and inflammation. By inhibiting this pathway, the drug helps keep the airways open and reduces allergic inflammation.

The specific dose of Montelukast Tecnigen is determined by the prescribing clinician based on the patient’s age, condition severity, and response to therapy. Common adult regimens involve a once‑daily tablet, but exact strength and frequency must follow the prescriber’s order.

Montelukast is classified as Pregnancy Category B, indicating no evidence of risk in animal studies and limited human data; it should be used only if the potential benefit justifies any possible risk. Small amounts are excreted in breast milk, so nursing mothers should discuss continuation with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Montelukast offers an oral, non‑steroidal option that targets leukotriene‑mediated inflammation, whereas inhaled corticosteroids act directly on airway inflammation via glucocorticoid receptors. Both can be used for asthma control, but inhaled steroids are generally more potent for severe disease, while Montelukast is useful as add‑on therapy or for patients preferring oral administration.

Store Montelukast Tecnigen tablets at ambient temperature, preferably below 25 °C, in the original container to protect from moisture and light. Keep the product out of reach of children and avoid exposing it to excessive heat or humidity.

Montelukast Tecnigen is taken orally, usually as a whole tablet with or without food, once daily in the evening. The exact timing and whether it should be taken with meals are determined by the prescribing clinician.

Serious adverse events include angioedema, severe skin reactions such as Stevens‑Johnson syndrome, eosinophilic pneumonia, hepatic injury, anaphylaxis, and neuropsychiatric effects like mood changes or suicidal thoughts. Patients should seek immediate medical attention if they experience any of these symptoms.

Montelukast is contraindicated in individuals with known hypersensitivity to the drug or any of its excipients. It should not be used as a rescue medication for acute asthma attacks, and patients with severe hepatic impairment should be evaluated carefully before initiation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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