Product image of Montelukast Teva (Montelukast) supplied by GNH India

Montelukast Teva

Active Ingredient:
Montelukast
Origin:
EU

Montelukast Teva (Montelukast)

Montelukast, the active ingredient in Montelukast Teva, is a leukotriene receptor antagonist presented as an oral tablet for oral use. It is used to manage asthma, allergic rhinitis, and exercise‑induced bronchoconstriction in adults and children.

GNH India supplies Montelukast Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The product meets European Union quality standards and is manufactured under strict GMP conditions. It is available for bulk distribution to meet global demand.

Manufacturer / TM Owner

Teva B.V

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Indications & Clinical Uses

Montelukast acts on the leukotriene pathway to control chronic respiratory and allergic conditions.

  • Asthma: reduces frequency of asthma attacks and improves lung function in patients with persistent asthma.
  • Allergic rhinitis: alleviates nasal congestion, sneezing and itching associated with seasonal allergies.
  • Exercise‑induced bronchoconstriction: prevents airway narrowing during and after physical activity.

How It Works

  • Montelukast selectively blocks the cysteinyl leukotriene receptor CysLT1 on airway smooth‑muscle cells, mast cells and eosinophils. By antagonizing this receptor, it inhibits the actions of leukotriene D4 and related mediators that cause bronchoconstriction, mucus secretion, vascular permeability and inflammatory cell recruitment, thereby reducing airway inflammation and hyper‑responsiveness, leading to improved airway patency.

Side Effects

Montelukast may cause a range of adverse reactions, which are categorized by frequency and severity.

Common Side Effects

  • Headache: mild to moderate headache reported.
  • Abdominal pain: occasional stomach discomfort.
  • Nausea: feeling of queasiness.
  • Diarrhea: loose stools.
  • Upper respiratory infection: mild cold‑like symptoms.

Serious or Rare Side Effects

  • Allergic reactions: rash, angioedema or anaphylaxis.
  • Mood changes: depression, suicidal thoughts or behavior.
  • Liver enzyme elevation: signs of hepatic dysfunction.
  • Blood dyscrasias: neutropenia or eosinophilia.

Precautions & Warnings

When prescribing Montelukast, clinicians should consider several safety precautions.

  • Pregnancy: safety not established; use only if potential benefit justifies risk.
  • Breastfeeding: assess risk; limited data available.
  • Hepatic impairment: monitor liver function, dose adjustment may be needed.
  • Neuropsychiatric effects: observe patients for mood changes or suicidal ideation.
  • Drug interactions: review concomitant medications for potential interactions.
  • Store at ambient temperature: keep below 25 °C in original packaging, protect from moisture and light.

Avoid Interactions

Montelukast can interact with other medicines, affecting its efficacy or safety.

Major Interactions (Avoid)

  • Phenobarbital, carbamazepine, phenytoin: enzyme inducers that may reduce montelukast plasma levels.
  • Rifampin: strong CYP3A4 inducer, may decrease therapeutic effect.

Moderate Interactions (Monitor Closely)

  • Warfarin: may increase INR; monitor coagulation parameters.
  • Protease inhibitors (e.g., ritonavir): may increase montelukast exposure; observe for side effects.
  • Fluconazole: CYP2C9 inhibitor, may raise montelukast levels.

Frequently Asked Questions

Montelukast Teva is prescribed for the long‑term management of asthma, for relief of symptoms associated with allergic rhinitis, and to prevent exercise‑induced bronchoconstriction. In each case the drug targets leukotriene‑mediated airway inflammation, helping to reduce the frequency of attacks, nasal congestion and exercise‑related breathing difficulties.

Montelukast works by selectively blocking the cysteinyl leukotriene receptor CysLT1 found on airway smooth‑muscle cells, mast cells and eosinophils. This antagonism prevents leukotrienes, especially leukotriene D4, from triggering bronchoconstriction, mucus production and inflammatory cell recruitment, thereby easing airway narrowing and allergic inflammation.

The prescribing clinician determines the dose based on the patient’s age, weight, specific indication and clinical response. Standard dosing recommendations exist for adults and children, but the final regimen is individualized and should follow the prescriber’s instructions.

Safety data for Montelukast in pregnancy are limited, and the drug is generally prescribed only when the potential benefit outweighs any possible risk to the fetus. During breastfeeding, only limited information is available; clinicians should evaluate the risk‑benefit profile for the infant before continuing therapy.

To place an order, submit an enquiry on the Montelukast Teva product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Montelukast belongs to the leukotriene receptor antagonist class, whereas inhaled corticosteroids target a broader range of inflammatory pathways. Montelukast is taken orally once daily and is particularly useful for patients who cannot tolerate inhaled steroids or need additional control for exercise‑induced symptoms. However, inhaled corticosteroids generally provide stronger anti‑inflammatory effects for persistent asthma.

Montelukast Teva tablets should be stored at ambient temperature, preferably below 25 °C, in the original container to protect them from moisture and light. Keep the product out of reach of children and avoid storing in areas with high humidity or direct sunlight.

Montelukast Teva is supplied as oral tablets that are swallowed whole with water. The medication can be taken with or without food, and it is usually taken once daily at the same time each day to maintain consistent blood levels. Patients should follow the dosing schedule prescribed by their healthcare provider.

The most serious adverse events associated with Montelukast include severe allergic reactions such as rash, angioedema or anaphylaxis, and neuropsychiatric effects like depression, suicidal thoughts or behavior. Hepatic dysfunction manifested by elevated liver enzymes and rare blood disorders such as neutropenia may also occur. Prompt medical attention is required if any of these symptoms develop.

Montelukast Teva should be avoided in individuals with known hypersensitivity to montelukast or any of the tablet excipients. Caution is also advised for patients with severe hepatic impairment, active psychiatric illness, or those taking medications that strongly induce its metabolism. Pregnant or breastfeeding women should only use it when clearly indicated by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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