Product image of Montelukast Teva (Montelukast Sodium) supplied by GNH India

Montelukast Teva

Active Ingredient:
Montelukast Sodium
Origin:
EU

Montelukast Teva (Montelukast Sodium)

Montelukast Sodium, the active ingredient in Montelukast Teva, is a leukotriene receptor antagonist presented as a medication for buccal, cutaneous, dental and nasal use. It is employed to manage asthma, allergic rhinitis and exercise‑induced bronchoconstriction in adults and children.

GNH India supplies Montelukast Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved documentation for global distribution.

Manufacturer / TM Owner

Teva Sweden Ab

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Indications & Clinical Uses

  • Montelukast Teva is a leukotriene receptor antagonist used to treat conditions mediated by cysteinyl leukotrienes.
  • Asthma: improves control of chronic airway inflammation and reduces frequency of exacerbations.
  • Allergic rhinitis: alleviates nasal congestion, sneezing and itching caused by allergic triggers.
  • Exercise‑induced bronchoconstriction: prevents narrowing of airways that occurs during or after physical activity.

How It Works

  • Montelukast selectively blocks the cysteinyl leukotriene receptor type 1 (CysLT1) on airway smooth‑muscle cells, vascular endothelium and inflammatory cells. By preventing leukotriene D4 and related mediators from binding, it reduces bronchoconstriction, mucus secretion, vascular permeability and inflammatory cell recruitment, thereby improving airway patency and nasal mucosa function.

Side Effects

Montelukast may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Headache
  • Abdominal pain
  • Nausea
  • Dizziness

Serious or Rare Side Effects

  • Angioedema or severe allergic reactions
  • Neuropsychiatric events such as depression or suicidal thoughts
  • Hepatic enzyme elevation or liver injury

Precautions & Warnings

  • When prescribing Montelukast, clinicians should consider several safety measures.
  • Assess asthma control: ensure baseline therapy is optimized before adding Montelukast.
  • Monitor neuropsychiatric symptoms: watch for mood changes, depression or suicidal ideation.
  • Avoid in patients with known hypersensitivity to Montelukast or any tablet components.
  • Adjust use in hepatic impairment: consider liver function monitoring in moderate to severe disease.
  • Store at room temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Montelukast can interact with other medicines that affect its metabolism or pharmacodynamic profile.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): may increase Montelukast plasma concentrations.
  • Phenobarbital and other potent enzyme inducers: may markedly reduce Montelukast effectiveness.

Moderate Interactions (Monitor Closely)

  • Rifampin: may lower drug levels, requiring clinical monitoring.
  • Fluconazole: moderate CYP3A4 inhibition may modestly raise exposure.
  • Carbamazepine: enzyme induction may decrease therapeutic effect.

Frequently Asked Questions

Montelukast Teva is indicated for the management of asthma, allergic rhinitis and exercise‑induced bronchoconstriction. By targeting leukotriene‑mediated pathways, it helps reduce airway narrowing, nasal congestion and related inflammatory symptoms in patients who require additional control beyond standard therapy.

Montelukast works by selectively blocking the cysteinyl leukotriene receptor type 1 (CysLT1). This inhibition prevents leukotrienes from triggering bronchoconstriction, mucus production and vascular leakage, thereby improving airflow in the lungs and reducing inflammation in the nasal passages.

The dose of Montelukast is individualized by the prescribing healthcare professional based on the patient’s age, weight and specific indication. Typical regimens differ for asthma, allergic rhinitis and exercise‑induced bronchoconstriction, and patients should follow the prescriber’s instructions without self‑adjusting the dose.

The pregnancy category for Montelukast is listed as unknown. It should only be used during pregnancy or lactation if the potential benefit justifies any possible risk to the fetus or infant. Women who are pregnant, planning pregnancy or breastfeeding should discuss the decision with their healthcare provider.

To place an order, submit an enquiry on the Montelukast Teva product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Montelukast belongs to the leukotriene receptor antagonist class, which provides an oral option for asthma and allergic rhinitis. Compared with inhaled corticosteroids, it is less potent for controlling severe asthma but offers a convenient once‑daily tablet form and can be used as add‑on therapy. Unlike antihistamines, it specifically targets leukotriene‑driven inflammation rather than histamine pathways.

Montelukast Teva should be stored at room temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and avoid storing it in areas with high humidity or temperature fluctuations to maintain potency.

Montelukast is typically supplied as oral tablets (or granules) that are taken once daily, with or without food, as directed by the prescriber. The medication is swallowed whole and should not be chewed or crushed unless a specific formulation advises otherwise.

Serious risks include neuropsychiatric events such as depression, suicidal thoughts or behavior, severe allergic reactions like angioedema, and potential liver injury indicated by elevated hepatic enzymes. Patients should seek immediate medical attention if they experience mood changes, swelling of the face or throat, or signs of liver dysfunction such as jaundice.

Montelukast should not be used by individuals with a known hypersensitivity to Montelukast sodium or any of the tablet’s excipients. Caution is also advised for patients with severe hepatic impairment, and it is generally avoided in those who have experienced serious neuropsychiatric reactions to leukotriene antagonists.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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