Product image of Montelukast Teva (Montelukast Sodium) supplied by GNH India

Montelukast Teva

Active Ingredient:
Montelukast Sodium
Origin:
EU

Montelukast Teva (Montelukast Sodium)

Montelukast, the active ingredient in Montelukast Teva, is a leukotriene receptor antagonist presented as a tablet for oral use. It is indicated for maintenance therapy of asthma, relief of allergic rhinitis symptoms, and prevention of exercise‑induced bronchoconstriction in both adults and children.

GNH India supplies Montelukast Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva B.V

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Indications & Clinical Uses

Montelukast acts on the leukotriene pathway to control airway inflammation and allergic symptoms.

  • Asthma: improves long‑term control and reduces the frequency of asthma attacks.
  • Allergic rhinitis: alleviates nasal congestion, sneezing and itchy eyes caused by seasonal or perennial allergens.
  • Exercise‑induced bronchoconstriction: prevents airway narrowing that occurs during or after physical activity.

How It Works

  • Montelukast selectively blocks the cysteinyl leukotriene receptor CysLT1, preventing leukotriene D4 and related mediators from binding. This inhibition reduces bronchoconstriction, vascular permeability, and inflammatory cell recruitment in the respiratory tract, thereby improving airway function and decreasing allergic inflammation.

Side Effects

Montelukast is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Upper respiratory tract infection: transient symptoms.
  • Abdominal pain: occasional discomfort.
  • Cough: non‑productive.
  • Diarrhoea: mild episodes.
  • Rash: mild skin irritation.

Serious or Rare Side Effects

  • Mood changes: including depression or suicidal thoughts.
  • Allergic reactions: such as angio‑edema or anaphylaxis.
  • Hepatotoxicity: elevated liver enzymes.
  • Stevens‑Johnson syndrome: severe skin eruption.
  • Churg‑Strauss syndrome: rare vasculitis.
  • Severe bronchospasm: paradoxical worsening of breathing.

Precautions & Warnings

Before prescribing Montelukast, consider the following safety measures.

  • Pregnancy: safety category unknown; weigh potential benefits against risks.
  • Breastfeeding: assess infant exposure; monitor for adverse effects.
  • Hepatic impairment: use with caution; monitor liver function.
  • Neuropsychiatric symptoms: observe for mood changes or suicidal ideation.
  • Drug interactions: review concomitant medications for potential interactions.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Montelukast may interact with other medicines; monitoring is advised.

Major Interactions (Avoid)

  • Phenobarbital: may reduce montelukast plasma concentrations.
  • Rifampin: can lower therapeutic levels of montelukast.

Moderate Interactions (Monitor Closely)

  • Antidepressants (e.g., SSRIs): may increase risk of neuropsychiatric events.
  • Warfarin: occasional reports of altered INR; monitor coagulation.
  • CYP3A4 inhibitors (e.g., ketoconazole): may modestly raise montelukast exposure.
  • CYP2C9 inhibitors (e.g., fluconazole): potential increase in drug levels.
  • Herbal supplements (e.g., St. John’s wort): may induce metabolism, reducing efficacy.

Frequently Asked Questions

Montelukast Teva is prescribed for the long‑term management of asthma, relief of symptoms associated with allergic rhinitis, and prevention of exercise‑induced bronchoconstriction. It works by targeting leukotriene‑mediated inflammation in the airways, helping to reduce asthma attacks and allergy symptoms.

Montelukast selectively blocks the cysteinyl leukotriene receptor CysLT1, preventing leukotriene D4 and related compounds from binding. This blockade reduces bronchoconstriction, mucus production, and inflammatory cell recruitment, leading to improved airway patency and decreased allergic inflammation.

The appropriate dose of Montelukast Teva is determined by the prescribing healthcare professional based on the patient’s age, condition, and clinical response. Dosage recommendations are provided in the product labeling and should be followed exactly as directed by the prescriber.

Safety data for Montelukast in pregnancy are limited, and the product is classified in an unknown pregnancy category. It should only be used if the potential benefit justifies the potential risk to the fetus. While breastfeeding, the drug may pass into milk; a risk‑benefit assessment is required.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Montelukast belongs to the leukotriene receptor antagonist class, offering an oral alternative to inhaled corticosteroids or long‑acting beta‑agonists. It is particularly useful for patients with aspirin‑sensitive asthma or those who prefer a once‑daily tablet, but it may be less effective for severe asthma that requires high‑dose inhaled steroids.

Montelukast Teva tablets should be stored at ambient temperature, preferably below 25 °C. Keep them in the original container, protect from moisture and direct sunlight, and ensure they are out of reach of children.

Montelukast Teva is taken orally, usually once daily in the evening, with or without food. The tablet should be swallowed whole with a glass of water. Patients should follow the dosing schedule prescribed by their healthcare provider.

Serious adverse events, though rare, include neuropsychiatric effects such as depression, suicidal thoughts, or mood changes, as well as severe allergic reactions like anaphylaxis, Stevens‑Johnson syndrome, and liver injury. Any concerning symptoms should prompt immediate medical evaluation.

Montelukast Teva is contraindicated in patients with known hypersensitivity to montelukast or any of the tablet’s excipients. Caution is advised for individuals with a history of severe psychiatric disorders, liver disease, or those taking interacting medications that may alter its effectiveness.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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