Product image of Montelukast Teva (Montelukast Sodium) supplied by GNH India

Montelukast Teva

Active Ingredient:
Montelukast Sodium
Origin:
EU

Montelukast Teva (Montelukast Sodium)

Montelukast, the active ingredient in Montelukast Teva, is a leukotriene receptor antagonist presented as an oral tablet for oral use. It is indicated for maintenance therapy of asthma, relief of allergic rhinitis symptoms, and prevention of exercise‑induced bronchoconstriction in adults and children.

GNH India supplies Montelukast Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved products to meet global healthcare needs. Our distribution network ensures reliable delivery across continents.

Manufacturer / TM Owner

Teva Pharma B.V.

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Indications & Clinical Uses

  • Montelukast acts on the leukotriene pathway to control airway inflammation and allergic symptoms.
  • Asthma (maintenance therapy): reduces frequency of bronchospasm episodes and improves overall lung function.
  • Allergic rhinitis: alleviates nasal congestion, sneezing, itching and watery discharge.
  • Exercise‑induced bronchoconstriction: prevents airway narrowing triggered by physical activity.

How It Works

  • Montelukast selectively antagonizes the cysteinyl leukotriene receptor CysLT1 located on airway smooth‑muscle cells and inflammatory cells. By blocking leukotriene D4 binding, it inhibits bronchoconstriction, mucus secretion, vascular permeability and inflammatory cell recruitment, thereby reducing airway inflammation and allergic responses.

Side Effects

Montelukast is generally well tolerated, but several adverse reactions have been reported.

Common Side Effects

  • Headache: mild to moderate intensity, often transient.
  • Abdominal pain: discomfort in the stomach area, usually resolves.
  • Cough: dry or productive, may be related to underlying condition.
  • Nausea: feeling of queasiness, sometimes accompanied by vomiting.

Serious or Rare Side Effects

  • Allergic reactions: rash, angioedema, or anaphylaxis requiring immediate medical attention.
  • Neuropsychiatric events: agitation, depression, anxiety, or suicidal thoughts reported in rare cases.
  • Hepatic dysfunction: elevated liver enzymes or hepatitis, necessitating monitoring.

Precautions & Warnings

  • Before initiating Montelukast therapy, consider the following precautions to ensure safe use.
  • Assess liver function: monitor patients with hepatic impairment as metabolism occurs in the liver.
  • Review psychiatric history: be alert for mood changes or suicidal thoughts, especially in adolescents.
  • Evaluate concomitant medications: avoid use with strong enzyme inducers that may reduce efficacy.
  • Consider age restrictions: safety and efficacy have been established for specific pediatric age groups.
  • Counsel on adherence: consistent daily dosing maximizes therapeutic benefit.
  • Store at ambient temperature below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Montelukast may interact with other medicines, altering its effectiveness or safety profile.

Major Interactions (Avoid)

  • Phenobarbital, carbamazepine, phenytoin: strong enzyme inducers that can markedly lower montelukast plasma concentrations.
  • Ritonavir: potent CYP3A4 inhibitor that may increase montelukast exposure and risk of adverse effects.

Moderate Interactions (Monitor Closely)

  • Fluconazole: moderate CYP3A4 inhibition may raise montelukast levels.
  • Rifampin: enzyme induction may reduce therapeutic effect.
  • Warfarin: possible alteration of anticoagulant effect; monitor INR.
  • Oral contraceptives: may slightly increase montelukast levels, generally not clinically significant.

Frequently Asked Questions

Montelukast Teva is a prescription oral medication containing the active ingredient montelukast sodium. It belongs to the leukotriene receptor antagonist class and is used for long‑term management of asthma, relief of symptoms of allergic rhinitis, and prevention of exercise‑induced bronchoconstriction in adults and children.

Montelukast selectively blocks the cysteinyl leukotriene receptor CysLT1 on airway smooth‑muscle cells and inflammatory cells. By antagonizing this receptor, it prevents leukotriene D4‑mediated bronchoconstriction, mucus secretion and vascular permeability, thereby reducing airway inflammation and allergic responses.

The specific dose and dosing schedule are determined by the prescribing healthcare professional based on the patient’s age, indication and clinical response. Montelukast is typically taken once daily in the evening, but the exact regimen should follow the prescriber’s instructions.

Safety data for montelukast in pregnancy are limited, and the product is classified as pregnancy category unknown. It should only be used if the potential benefit justifies any potential risk to the fetus. Caution is also advised during breastfeeding, as the drug is excreted in breast milk; a healthcare provider should evaluate the risk‑benefit balance.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Montelukast offers an oral, once‑daily alternative to inhaled corticosteroids and long‑acting β‑agonists for maintenance therapy. Unlike bronchodilators, it targets leukotriene‑mediated inflammation, which can be beneficial for patients with aspirin‑exacerbated respiratory disease or those who prefer oral therapy. It is often used as add‑on therapy rather than a sole replacement for inhaled steroids.

Montelukast Teva should be stored at ambient temperature below 25 °C, in the original packaging to protect it from moisture and light. Keep the product out of reach of children and do not use it after the expiry date printed on the label.

Montelukast Teva is taken orally, usually as a tablet, with or without food. The tablet should be swallowed whole with a glass of water. Dosing time is generally recommended in the evening to align with the nocturnal rise in leukotriene production, but patients should follow their prescriber’s directions.

Although uncommon, serious adverse reactions can include severe allergic responses such as anaphylaxis, neuropsychiatric events like depression or suicidal thoughts, and liver injury indicated by elevated enzymes or hepatitis. Patients should seek immediate medical attention if they experience rash, mood changes, jaundice or other concerning symptoms.

Montelukast is contraindicated in patients with known hypersensitivity to montelukast sodium or any of the tablet’s excipients. Caution is also advised for individuals with severe hepatic impairment, active psychiatric disorders, or those taking strong enzyme‑inducing drugs that may reduce efficacy. The prescriber should evaluate suitability before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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