Product image of Montelukast Teva (Montelukast Sodium) supplied by GNH India

Montelukast Teva

Active Ingredient:
Montelukast Sodium
Origin:
EU

Montelukast Teva (Montelukast Sodium)

Montelukast, the active ingredient in Montelukast Teva, is a leukotriene receptor antagonist presented as an oral tablet for oral use. It is used to manage asthma, allergic rhinitis, and exercise‑induced bronchoconstriction in adults and children. By selectively blocking cysteinyl leukotriene receptors, it helps reduce airway inflammation, bronchoconstriction, and related symptoms.

GNH India supplies Montelukast Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution.

Manufacturer / TM Owner

Teva Gyógyszergyár Zrt

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Indications & Clinical Uses

Montelukast is a leukotriene receptor antagonist used to treat conditions driven by leukotriene‑mediated inflammation.

  • Asthma: improves long‑term control and reduces the frequency of exacerbations.
  • Allergic rhinitis: relieves nasal congestion, sneezing, itching and rhinorrhea.
  • Exercise‑induced bronchoconstriction: prevents airway narrowing that occurs during physical activity.

How It Works

  • Montelukast selectively antagonizes the cysteinyl leukotriene receptor CysLT1, blocking the action of leukotriene D4 and related mediators. This inhibition reduces leukotriene‑induced bronchoconstriction, vascular permeability, and inflammatory cell recruitment in the airways, thereby improving respiratory function and decreasing allergic symptoms.

Side Effects

Montelukast is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Abdominal pain or dyspepsia.
  • Cough or throat irritation.
  • Dizziness or fatigue.
  • Nasopharyngitis.
  • Diarrhoea.

Serious or Rare Side Effects

  • Neuropsychiatric events such as agitation, depression, suicidal thoughts or behaviour.
  • Severe allergic reactions including rash, angio‑edema or anaphylaxis.
  • Hepatic enzyme elevations.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Parotid gland enlargement.
  • Blood dyscrasias (rare).

Precautions & Warnings

When prescribing Montelukast, clinicians should consider several safety aspects.

  • Assess asthma control: ensure optimal inhaled therapy before adding Montelukast.
  • Monitor neuropsychiatric symptoms: watch for mood changes, depression or suicidal ideation.
  • Use with caution in hepatic impairment: dose adjustment may be required.
  • Avoid in patients with known hypersensitivity to Montelukast or any excipients.
  • Review concomitant medications for potential interactions.
  • Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Montelukast may interact with other medicines, requiring attention to the level of risk.

Major Interactions (Avoid)

  • Phenobarbital, rifampin or St. John's wort: strong enzyme inducers that can markedly reduce Montelukast plasma concentrations.

Moderate Interactions (Monitor Closely)

  • Warfarin: possible alteration of anticoagulant effect; monitor INR.
  • Carbamazepine: may modestly decrease Montelukast exposure.
  • Fluconazole: potential increase in Montelukast levels.
  • Oral contraceptives: Montelukast may slightly reduce hormonal efficacy; advise backup contraception if needed.

Frequently Asked Questions

Montelukast Teva contains the active ingredient Montelukast sodium and is indicated for the long‑term management of asthma, relief of symptoms of allergic rhinitis, and prevention of exercise‑induced bronchoconstriction. It works by reducing airway inflammation and narrowing caused by leukotrienes, helping patients achieve better respiratory control.

Montelukast selectively blocks the cysteinyl leukotriene receptor CysLT1, preventing leukotriene D4 from binding. This inhibition stops the cascade that leads to bronchoconstriction, mucus secretion, and airway edema, thereby improving breathing and reducing allergic symptoms.

The dose of Montelukast Teva is determined by the prescribing healthcare professional based on the patient’s age, condition and clinical response. The prescriber will select the appropriate strength and dosing schedule, which may differ for asthma, allergic rhinitis or exercise‑induced bronchoconstriction.

Safety data for Montelukast during pregnancy are limited, and the drug should only be used if the potential benefit justifies any possible risk to the fetus. Limited information suggests that small amounts are excreted in breast milk; therefore, a risk‑benefit assessment is required before use in nursing mothers.

To place an order, submit an enquiry on the Montelukast Teva product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Montelukast belongs to the leukotriene receptor antagonist class, offering an oral alternative to inhaled corticosteroids or long‑acting beta‑agonists. It is particularly useful for patients with aspirin‑sensitive asthma or those who prefer a non‑inhaled option. While it may be less potent than high‑dose inhaled steroids for severe asthma, it provides valuable add‑on therapy and benefits for allergic rhinitis.

Montelukast Teva tablets should be stored at room temperature, below 25 °C, in the original blister pack or container. Protect the product from moisture, excessive heat and direct sunlight to maintain stability throughout its shelf life.

Montelukast Teva is taken orally, usually as a whole tablet swallowed with water. It can be taken with or without food, and the timing (e.g., in the evening for asthma) is determined by the prescribing clinician based on the therapeutic goal.

The most serious risks include neuropsychiatric events such as agitation, depression, suicidal thoughts or behaviours, and severe allergic reactions like anaphylaxis, Stevens‑Johnson syndrome or angio‑edema. Patients should be instructed to seek immediate medical attention if they experience mood changes, rash, swelling or breathing difficulties.

Montelukast Teva is contraindicated in individuals with known hypersensitivity to Montelukast sodium or any of the tablet’s excipients. Caution is also advised for patients with severe hepatic impairment, and it should be avoided in those who have experienced serious neuropsychiatric or allergic reactions to the drug.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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