Product image of Montelukast Teva (Montelukast Sodium) supplied by GNH India

Montelukast Teva

Active Ingredient:
Montelukast Sodium
Origin:
EU

Montelukast Teva (Montelukast Sodium)

Montelukast, the active ingredient in Montelukast Teva, is a leukotriene receptor antagonist presented as an oral tablet for oral use. It is indicated for maintenance therapy of asthma, relief of allergic rhinitis symptoms, and prevention of exercise‑induced bronchospasm in appropriate patients.
GNH India supplies Montelukast Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva Pharma S.L.U.,

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Indications & Clinical Uses

Montelukast acts on the leukotriene pathway to control inflammatory airway conditions.

  • Asthma: provides maintenance therapy that reduces the frequency of bronchospastic episodes.
  • Allergic rhinitis: alleviates nasal congestion, sneezing and itching caused by allergen exposure.
  • Exercise‑induced bronchospasm: prevents airway narrowing that can occur during physical activity.

How It Works

  • Montelukast selectively antagonizes the cysteinyl leukotriene receptor CysLT1, blocking the binding of leukotrienes D4, C4 and E4. This inhibition reduces leukotriene‑mediated bronchoconstriction, vascular permeability, and inflammatory cell recruitment in the respiratory tract, thereby improving airway patency and decreasing allergic inflammation.

Side Effects

Montelukast is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Abdominal pain: occasional discomfort.
  • Cough: transient irritation.
  • Nausea: occasional upset stomach.
  • Dizziness: brief episodes.
  • Fatigue: mild tiredness.

Serious or Rare Side Effects

  • Allergic reactions: rash, angioedema or anaphylaxis.
  • Neuropsychiatric events: mood changes, depression or suicidal thoughts.
  • Hepatic enzyme elevation: abnormal liver function tests.
  • Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Blood disorders: eosinophilia or neutropenia.

Precautions & Warnings

Before initiating therapy, clinicians should consider several safety aspects.

  • Liver function assessment: monitor patients with existing hepatic disease.
  • Psychiatric history review: observe for mood alterations or suicidal ideation.
  • Renal impairment caution: adjust use in severe renal dysfunction.
  • Hypersensitivity avoidance: do not prescribe to patients with known allergy to montelukast or excipients.
  • Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Montelukast may interact with other medicines, requiring attention to the interaction level.

Major Interactions (Avoid)

  • Strong CYP3A4 inducers (e.g., rifampin): may reduce montelukast exposure.
  • Phenobarbital: can lower therapeutic levels.
  • Concomitant leukotriene modifiers (e.g., zafirlukast): increase risk of adverse effects.

Moderate Interactions (Monitor Closely):\n- Antidepressants (SSRIs, SNRIs): may heighten neuropsychiatric risk.

  • Antihistamines: additive sedation in sensitive individuals.
  • Warfarin: possible variability in INR, requiring closer monitoring.

Frequently Asked Questions

Montelukast Teva is prescribed as a maintenance treatment for asthma, to relieve symptoms of allergic rhinitis such as nasal congestion and sneezing, and to prevent bronchospasm triggered by exercise. It works by targeting leukotriene‑mediated inflammation in the airways.

Montelukast blocks the cysteinyl leukotriene receptor CysLT1, preventing leukotrienes D4, C4 and E4 from binding. This inhibition reduces bronchoconstriction, mucus production, and inflammatory cell recruitment, leading to improved airway function and reduced allergic symptoms.

The appropriate dose of Montelukast Teva is determined by the prescribing healthcare professional based on the patient’s age, indication and clinical response. Dosage may differ for asthma, allergic rhinitis or exercise‑induced bronchospasm, and should follow the prescriber’s instructions.

Safety data for Montelukast in pregnancy and lactation are limited. The product is classified as pregnancy category unknown, so clinicians should weigh potential benefits against risks and discuss use with the patient. Breastfeeding mothers should also consult their healthcare provider.

To place an order, submit an enquiry on the Montelukast Teva product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Montelukast belongs to the leukotriene receptor antagonist class, offering an oral alternative to inhaled corticosteroids or long‑acting beta‑agonists. It is especially useful for patients who prefer a tablet form or have aspirin‑exacerbated respiratory disease. While effective for maintenance, it is generally used in combination with inhaled therapies for optimal control.

Montelukast tablets should be stored at room temperature, below 25 °C, in the original blister pack or container. Protect them from moisture, excessive heat and direct sunlight to maintain product stability throughout its shelf life.

Montelukast Teva is taken orally as a tablet. The tablet should be swallowed whole with a glass of water, preferably at the same time each day. It can be taken with or without food, according to the prescriber’s guidance.

Serious adverse events include allergic reactions such as rash, angioedema or anaphylaxis, and neuropsychiatric effects like depression, mood swings or suicidal thoughts. Rare but severe skin reactions (Stevens‑Johnson syndrome) and significant liver enzyme elevations have also been reported. Patients should seek immediate medical attention if these occur.

Montelukast is contraindicated in individuals with known hypersensitivity to montelukast sodium or any of its excipients. Caution is advised for patients with severe hepatic impairment, active psychiatric disorders, or those taking interacting medications listed under major interactions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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